An image taken by Paul Odgren has been selected as one of ten winning images in the the BioArt 2014 competition hosted by FASEB, Federation of American Societies for Experimental Biology. Through the BioArt competition, FASEB aims to share the beauty and excitment of biological research with the public. FASEB encourages the submission of captivating, high-resolution images and videos represetning cutting edge, 21st Century biomedical and life science research. Ten images and two videos were selected as winners for the 2014 competion. This image was also selected to be displayed in the elevator lobby of the 7th floor of the school near the Cell and Developmental Biology Department.
Paul Odgren's research focus is on bone development and healing. The description submitted with the image states: During normal bone development and fracture healing, cartilage is transformed into bone. Osteoclasts, a specialized type of cell, eat the cartilage, creating a passageway for blood vessels, marrow, and other bone cells. In this image of cartilage (purple and white) from a young mouse femur, osteoclasts (red) surround a blood vessel filled with red blood cells (yellow). In contrast to normal osteoclasts, the cells seen here have only a single nucleus due to the lack of gene involved in osteoclast development. Funding from the NIH National Institute of Arthritis and Musculoskeletal and Skin Diseases supports this research program that aims to understand how large, bone resorbing osteoclasts form, and whether preventing them from fusing together is a way to control bone loss in osteoporosis, arthritis, or other conditions.