Freedman Laboratory: Faculty and Research Members

    

Dr. Jane E. Freedman is a Professor of Medicine at University of Massachusetts Medical School, attends in the Division of Cardiology and is Director of Translational Research for the UMass Memorial Heart & Vascular Center.  Dr. Freedman graduated from YaleUniversity, Tufts University School of Medicine, and completed residency and cardiology fellowship at the Massachusetts GeneralHospital and Brigham and Women’s Hospital, respectively.  Dr. Freedman has received young investigator awards from both the AHA and the ACC, was been elected to the A.S.C.I. and the A.U.C., and is an Associate Editor for CirculationThe major research initiatives in Dr. Freedman’s laboratory emphasize the regulation of pathways contributing to atherothrombotic disease and how these factors contribute to acute coronary syndromes.  She oversees two research programs; the first is a basic science laboratory that examines the role of immunity, infection, and inflammation on atherothrombotic disease.  The second facility uses high-throughput, nano-chip, and RNAseq technologies to study gene expression and provide translational data for a wide range of projects and has measured gene expression in thousands of clinical samples for dozens of studies.  Dr. Freedman is on the Steering Committee for the Framingham Heart Studies SABRe biomarker project and the Principal Investigator for two (UH2/UH3 and U01) NIH Common Fund Studies investigating the role of extracellular RNAs in human populations and disease.

   

  Co-Director:
Kahraman Tanriverdi, PhD
Research Assistant Professor, Department of Medicine

 

Dr. Milka Koupenova  is an Instructor of Medicine at University of Massachusetts Medical School.  Dr. Koupenova received her PhD in Biochemistry from Boston University, MA and her BS in Biochemistry from University of California Los Angeles, CA.  She joined Dr. Freedman’s group for her postdoctoral training in 2011 and became a junior faculty in 2016. Dr. Koupenova research is focused on the contribution of platelets to the immune response during viral infections and the consequent implication of that response to cardiovascular disease. Dr. Koupenova is also interested in the sex differences of platelet immunity and implications of viral infections to platelet production. Dr. Koupenova is a 2015 recipient of the Translational Research Training Award from ASH & EHA and is finalist for the 2018 Kenneth M. Brinkhous Young Investigator Award in Thrombosis by the AHA. Dr. Koupenova is currently receiving grant support from the AHA.

Vitzeva

 

Dr. Olga Vitseva is a Research Associate at University of Massachusetts Medical School in the Department of Medicine, Division of Cardiovascular Medicine. She received her PhD in Biochemistry from Institute of Basic Biological Problems, Russian Academia of Science. She has been a longstanding member of Dr. Freedman’s laboratory. Her research interest is focused on the role of platelets in inflammatory responses. 

 

   

Heather Corkrey is a Research Associate at the University of Massachusetts Medical School, in the Division of Cardiovascular Medicine. She received her MS in Animal Science from the University of California, Davis, and her BS in Animal Science from Cornell University. With experience in both academia and industry, she joined Dr. Freedman’s group in January of 2016.

 

 

 Dr. Marzieh Mirhashemi is an AHA SFRN postdoctoral fellow. Dr. Mirhashemi joined Dr. Freedman's lab in 2017. She is focusing on identifying metabolic abnormalities in platelets as a result of obesity, and preclinical markers for heart failure utilizing data and samples from various clinical and cohort studies. Dr. Mirhashemi’s interests are gene expression and cardiac remodeling.

       
Lea Beaulieu
Lea Beaulieu, PhD
Instructor, Department of Medicine                           
lea.beaulieu@umassmed.edu
   
       
 Ekaterina Mikhalev Ekaterina Mikhalev, BS
Research Associate, Department of Medicine                      
ekaterina.mikhalev@umassmed.edu

 

   
       
Hyungjoo Kang Hyung-Joo Kang, MS
Biostatistician III, Department of Medicine                      
hyung-joo.kang@umassmed.edu
   
       

 

 

 

 Evangelia Malahias, BS
Research Associate, Department of Medicine