Guodong Tie

 

 

  

Research Instructor 

 

UMassMed Faculty Page

Inventions:

Title: Tet1-Dependent Differentiation of Human Hematopoietic Stem Cell towards NKT And γδ T Cells. UMMS15-18; Patent Pending. 

• The invention provides methods of producing hematopoietic stem cells (HSCs) with increased differentiation towards natural killer T cells (NKT) and gamma delta T cells (γδ T cells) for cancer immunotherapy. The HSCs are also functionally superior in their capacity to kill tumor cells, as injection of HSCs overexpressing Tet1 eliminates all of the carcinoma stages of neoplasia. 

• Technology: Biologics
• Applications: Cancer, Breast cancer, Colon cancer, Lymphoid malignancies, Myeloma, Ovarian cancer, Prostate cancer, Renal cell carcinoma, Stem cell/Stem cell Therapy, Immunotherapy

 

Innovation Topics: Biologics, Cancer, Breast cancer, Colon cancer, Lymphoid malignancies, Myeloma, Ovarian cancer, Prostate cancer, Renal cell carcinoma, Stem cell/Stem cell Therapy, Immunotherapy