Peter A Rice

UMassMed Faculty Page

Inventions:

Title: PEPTIDE MIMICS OF CONSERVED GONOCOCCAL EPITOPES AND METHODS AND COMPOSITIONS USING THEM. UMMS10-04; Patent 7,871,628 

• The present invention relates to peptide mimics of a conserved gonococcal lipo-oligosaccharide (LOS) epitope of Neisseria gonorrhoeae, which epitope is not found on human blood group antigens. This invention also relates to methods and compositions using such peptide mimics for the prophylaxis of gonorrheal infections. 

  • Technology: Biologics
    
  • Applications: Infectious Disease, Neisseria gonorrhoeae, Sexually transmitted disease (STD)
  • Patent Expiration Dates: 2027-02-26

Title: Monoclonal Antibody Producing Cell Lines called 2C3-like Cell Lines and the 2C3-like Antibodies that They Produce. UMMS08-34; Patent Pending.

• This new invention spans from the discovery of novel antibodies and an antigen binding fragment that bind surface membrane proteins of Neisseria species (e.g. N. gonorrhoeae and N. meningitidis). This invention can be applied to diagnostic, therapeutic, and potentially preventative methods for managing Neisseria infections. 

  • Technology: Biologics, Diagnostics
    
  • Applications: Antibody, Infectious Disease, Neisseria gonorrhoeae, N. meningitides, Neisseria species

Title: Peptide Mimics of Conserved Gonococcal Epitopes and Methods and Compositions Using Them. UMMS10-06; Patent 7,871,628 

• The present invention relates to peptide mimics of a conserved gonococcal lipo-oligosaccharide (LOS) epitope of Neisseria gonorrhoeae, which epitope is not found on human blood group antigens. This invention also relates to methods and compositions using such peptide mimics for the prophylaxis of gonorrheal infections. 

  • Technology: Small Molecules 
  • Applications: Infectious Disease, Neisseria gonorrhoeae, Sexually transmitted disease (STD)
  • Patent Expiration Dates: 2027-02-26

Title: METHODS, COMPOSITIONS AND VACCINES RELATING TO NEISSERIA MENINGITIDIS ANTIBODIE. UMMS09-08; Patent 9,475,864

• This invention reports the discovery of serum IgG of different individuals that block antibody (Ab) activity targeted against Neisseria membrane lipoprotein H.8. Blocking Ab activity may predispose such individuals to developing invasive disease with N. meningtitidis or decrease the efficacy of vaccines. This finding can explain the variability between individual susceptibility and provide new avenue for treatment and increasing efficacy of existing treatments.

  • Technology: Small Molecules, Biologics
    
  • Applications: New antibody treatment, Antibiotics/Antibiotic treatment, N. meningitides, Vaccines
    
  • Patent Expiration Date: 2030-05-17

 

Innovation Topics: Biologics, Infectious Disease, Neisseria gonorrhoeae, Sexually transmitted disease (STD), Diagnostics, Antibody, N. meningitides, Neisseria species, Small Molecules, New antibody treatment, Antibiotics/Antibiotic treatment, Vaccines