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Peter A Rice

UMassMed Faculty Page

Inventions:

Title: PEPTIDE MIMICS OF CONSERVED GONOCOCCAL EPITOPES AND METHODS AND COMPOSITIONS USING THEM. UMMS10-04; Patent 7,871,628 

  • The present invention relates to peptide mimics of a conserved gonococcal lipo-oligosaccharide (LOS) epitope of Neisseria gonorrhoeae, which epitope is not found on human blood group antigens. This invention also relates to methods and compositions using such peptide mimics for the prophylaxis of gonorrheal infections. 

Title: Monoclonal Antibody Producing Cell Lines called 2C3-like Cell Lines and the 2C3-like Antibodies that They Produce. UMMS08-34; Patent Pending.

Title: Peptide Mimics of Conserved Gonococcal Epitopes and Methods and Compositions Using Them. UMMS10-06; Patent 7,871,628 

  • The present invention relates to peptide mimics of a conserved gonococcal lipo-oligosaccharide (LOS) epitope of Neisseria gonorrhoeae, which epitope is not found on human blood group antigens. This invention also relates to methods and compositions using such peptide mimics for the prophylaxis of gonorrheal infections. 

Title: METHODS, COMPOSITIONS AND VACCINES RELATING TO NEISSERIA MENINGITIDIS ANTIBODIEUMMS09-08; Patent 9,475,864

  • This invention reports the discovery of serum IgG of different individuals that block antibody (Ab) activity targeted against Neisseria membrane lipoprotein H.8. Blocking Ab activity may predispose such individuals to developing invasive disease with N. meningtitidis or decrease the efficacy of vaccines. This finding can explain the variability between individual susceptibility and provide new avenue for treatment and increasing efficacy of existing treatments.

 

Innovation TopicsBiologicsInfectious DiseaseNeisseria gonorrhoeaeSexually transmitted disease (STD)DiagnosticsAntibodyN. meningitidesNeisseria speciesSmall MoleculesNew antibody treatmentAntibiotics/Antibiotic treatmentVaccines