Abraham L Brass

 

 

 

 

UMassMed Faculty Page

Inventions:

Title: Lanatoside C Inhibition of Zika Virus Infection. UMMS16-60; Patent Pending. 

• This new discovery has found that cardiac glycoside Lanatoside C - an inhibitor of dengue virus, flavivirus Kunjin, alphavirus Chickingunya, and enterovirus 71 - also effectively stops replication of the Zika virus. This invention discloses treatment of Zika virus with Lanatoside C alone and in combination with ribavirin or ivermectin.

  • Technology: Small Molecules 
  • Applications: Infectious Disease, Zika virus, Antiviral

Title: TARGETING HEPATITIS B VIRUS (HBV) HOST FACTORS. UMMS15-60; Patent 9,771,590. 

• This invention discloses the first ever genetic screen to identify Hepatitis B virus host factors. The invention further encompasses the factors, such as Zinc finger, CCHC domain containing 14 (ZCCHC14), identified by those methods and methods of treating Hepatitis B virus infections by targeting those factors.

• Technology: Research Tools 
  
• Applications: Infectious Disease, HBV, Antiviral, Cirrhosis, Hepatitis

 

Innovation Topics: Small Molecules, Infectious Disease, Zika virus, Antiviral, Research Tools, Infectious Disease, HBV, Antiviral, Cirrhosis, Hepatitis