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Abraham L Brass

 

 

 

 

UMassMed Faculty Page

Inventions:

Title: Lanatoside C Inhibition of Zika Virus Infection. UMMS16-60; Patent Pending. 

  • This new discovery has found that cardiac glycoside Lanatoside C - an inhibitor of dengue virus, flavivirus Kunjin, alphavirus Chickingunya, and enterovirus 71 - also effectively stops replication of the Zika virus. This invention discloses treatment of Zika virus with Lanatoside C alone and in combination with ribavirin or ivermectin.

Title: TARGETING HEPATITIS B VIRUS (HBV) HOST FACTORS. UMMS15-60; Patent 9,771,590

  • This invention discloses the first ever genetic screen to identify Hepatitis B virus host factors. The invention further encompasses the factors, such as Zinc finger, CCHC domain containing 14 (ZCCHC14), identified by those methods and methods of treating Hepatitis B virus infections by targeting those factors.

 

Innovation Topics: Small MoleculesInfectious DiseaseZika virusAntiviralResearch ToolsInfectious DiseaseHBVAntiviral, CirrhosisHepatitis