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Publications

  • MD. Zulfikar and Robert C. Brewster (2021) DControlling gene expression timing through gene regulatory architecture, In review at PLoS Comp Bio.
  • Sunil Guharajan, Shivani Chhabra, Vinuselvi Parisutham, Robert C. Brewster (2021) Quantifying the regulatory role of individual transcription factors in Escherichia coli, accepted at Cell Reports.
  • Vinuselvi Parisutham, Sunil Guharajan, Shivani Chhabra and Robert C. Brewster (2021) Tunable transcription factor library for robust quantification of gene regulatory properties in Escherichia coli, in preparation.
  • Zulfikar Ali, Vinuselvi Parisutham, Sandeep Chuobey, Robert C. Brewster (2020) Inherent regulatory asymmetry emanating from network architecture in a prevalent autoregulatory motif. eLife 9:e56517
  • Colin C. Conine, Marina Krykbaeva, Lina Song, Robert C. Brewster, Nir Friedman, Oliver J. Rando (2020), Flexibility and constraint in preimplantation gene regulation in mouse, in review at Elife.
  • Zulfikar Ali, Sandeep Chuobey, Dipjyoti Das, Robert C. Brewster (2020) Probing mechanisms of transcription elongation through cell-to-cell variability of RNA polymerase. Biophysical Journal 118(7).
  • Jote T. Bulcha, Gabrielle E. Giese, Md. Zulfikar Ali, Yong-Uk Lee, Melissa D.Walker, Amy D.Holdorf, L. Safak Yilmaz, Robert C.Brewster, Albertha J.M.Walhout (2019). A Persistence Detector for Metabolic Network Rewiring in an Animal. Cell Reports 26, 460-468.
  • Jasper Landman, Robert C. Brewster, Franz M. Weinert, Rob Phillips, Willem K. Kegel (2017) Self-consistent theory of transcriptional control in complex regulatory architectures, PLoS ONE, 12(7):e0179235 [manuscript]
  • Dipjyoti Das, Supravat Dey, Robert C. Brewster*, Sandeep Chuobey* (2017) Effect of transcription factor resource sharing on gene expression noise, PLoS Computational Biology, 13, 4 [manuscript]
  • Hernan G. Garcia, Robert C. Brewster and Rob Phillips (2016) Using synthetic biology to make cells tomorrow’s test tubes, Integrative Biology, 8, 431 [manuscript]
  • Geoffrey A. Lovely, Robert C. Brewster, David G. Schatz, David Baltimore and Rob Phillips (2015) Single-molecule analysis of RAG-mediated V(D)J DNA cleavage, PNAS, 112 (14), E1715-E1723 [manuscript, SI]
  • Daniel L. Jones*, Robert C. Brewster* and Rob Phillips (2014) Cell-to-Cell Variability in Gene Expression is Governed by Promoter Architecture, Science, 346 (6216), 1533-1536 [manuscript, SI]
  • Franz M. Weinert*, Robert C. Brewster*, Mattias Rydenfelt, Rob Phillips and Willem K. Kegel (2014) Scaling of Gene Expression with Transcription Factor Fugacity, Physical Review Letters113, 258101 [manuscript]
  • Robert C. Brewster*, Franz M. Weinert*, Hernan G. Garcia, Linda Song, Mattias Rydenfelt and Rob Phillips (2014) The Transcription Factor Titration Effect Dictates Level of Gene Expression, Cell156(6) [manuscript, SI
      This work has been highlighted in:
    • See Press release
    • "Tuning expression by numbers", Nature Methods11(475), 2014 [text]
    • "Target competition: transcription factors enter the limelight", Karreth, FA, Tay, Y, Pandolfi, P, Genome Biology15(114), 2014 [text]
  • Benoit Palmieri, Tetsuya Yamamoto, Robert C. Brewster and Samuel A. Safran (2014) Line active molecules promote inhomogeneous structures in membranes: Theory, Simulations and Experiments, Advances in Colloid and Interface Science (issue in honor of Wolfgang Helfrich)208, 58-65 [manuscript]
  • Robert C. Brewster*, Daniel L. Jones* and Rob Phillips (2012) Tuning Promoter Strength through RNA Polymerase Binding Site Design in Escherichia coli, PLoS Computational Biology8(12), e1002811 [manuscript]
  • YongSeok Jho, Robert C. Brewster, Samuel A. Safran and Philip A. Pincus (2011) Long-Range Interaction between Heterogeneously Charged Membranes, Langmuir27(8), 4439-4446 [manuscript]
  • Robert C. Brewster and Samuel A. Safran (2010) Line active hybrid lipids determine domain size in phase separation of saturated and unsaturated lipids, Biophysical Journal Letters98, L21-Ld3 [manuscript]
  • Tetsuya Yamamoto, Robert C. Brewster and Samuel A. Safran (2010) Chain ordering of hybrid lipids can stabilize domains in saturated/hybrid/cholesterol lipid membranes, Europhysics Letters91, 28002 [manuscript]
  • Robert C. Brewster, Philip A. Pincus and Samuel A. Safran (2009) Hybrid Lipid as Biological Surfactants, Biophysical Journal97, 1087-194 [manuscript]