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X-ray Crystallography Core obtains state-of-the-art X-ray detector

Date Posted: Thursday, September 16, 2021

new XrayThe X-ray crystallography core has recently obtained a new state-of-the-art X-ray detector using RCA Capital, Dean and BMP departmental funds.  The HyPix-6000HE Hybrid Photon Counting (HPC) detector permits direct sensing of X-ray photons, rather than relying on phosphor screens to convert X-ray photon energy to visible light that are then detected by the CCD detector.  As a result, HPC detectors, which are also much more reliable, have greater spatial sensitivity and much lower background than CCD detectors, permitting acquisition of much higher quality and higher resolution diffraction data.  We have already determined several new high-resolution structures with this new detector.  Thus, this detector will allow the X-ray crystallography core facility to continue ground-breaking structural biological research, including structure-based drug design, at UMMS for years to come.


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