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Rhind Lab awarded R01 grant

Date Posted: Monday, March 23, 2020


The Rhind Lab has been awarded an R01 to investigate one of the last fundamental mysteries in cell biology: How cells know how big they are.  

Cell size has been studied for over 100 years, but the mechanisms of cell size control are still mysterious.  Recent work in budding budding and fission yeast, built on decades of yeast cell cycle physiology and genetics, supports the model that cell size is regulated by size-dependent expression of cell cycle regulators.  The Rhind Lab has identified two such proteins in fission yeast, Cdc25 and Cdc13.  The new award will fund work to understand how these ‘sizer’ protein are expressed in a size dependent manner, unlike all other proteins in the cell.

 

For more about the Rhind Lab, please visit www.umassmed.edu/rhindlab