National Mouse Metabolic Phenotyping Center at UMASS is designed to provide the scientific community with sophisticated and standardized experimental tools for the purpose of investigating transgenic mouse models and understanding obesity, diabetes and its complications. The UMPC is composed of multidisciplinary group of investigators at the UMass Medical School and consists of the following Phenotyping Cores:
- Metabolism Core performs elegant and non-invasive metabolic experiments to assess insulin sensitivity, glucose/lipid/protein metabolism, body composition and energy balance in conscious mice.
- Analytical Core utilizes clinical chemistry analyzer and Luminex to perform high-throughput measurement of serum/tissue hormones, metabolites and cytokines known to affect metabolism.
- Cardiovascular Core applies a state-of-the-art imaging platform to non-invasively assess cardiac structure and function and vascular imaging to examine cardiovascular diseases.