Analytical Core

The Analytical Core performs a high-throughput measurement of serum and tissue levels of hormones, metabolites and cytokines that are known to affect metabolism.

  • Measures serum and tissue levels of hormones (insulin, leptin, adiponectin), cytokines (TNF-a, IL-6, IL-1) and chemokines (MCP, MIP, VEGF) using Luminex (photo).
  • Measures serum and tissue levels of metabolites (lipid and hepatic panel) and electrolytes using Cobas Clinical Chemistry Analyzer.
  • Performs standardized biochemical procedures to measure intracellular metabolism in individual organs.
  • Performs complex molecular procedures to assess intracellular signaling pathway associated with insulin, metabolism and inflammation.

David M. Harlan, M.D.
William and Doris Krupp Professor of Medicine 
Co-Director, Diabetes Center of Excellence 
UMass Memorial Medical Center and 
Professor of Medicine and Pediatrics 
Chief, Division of Diabetes 
University of Massachusetts Medical School 
508-856-3800 (phone)

 Harlan 2010

Randall Friedline, Ph.D.
Instructor of Molecular Medicine
508-856-8791 (phone)

Randall Friedline


University of Massachusetts Medical School
368 Plantation Street
The Albert Sherman Center
9th Floor, Room 1015
Worcester, MA 01605

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