Analytical Core

The Analytical Core provides comprehensive analysis of hormones, cytokines, chemokines, metabolites, and electrolytes across multiple platforms (serum, tissues, homogenates, and cells) as well as liver function analysis using state-of-the-art instrumentation. The Core services enhance whole body metabolic characterization and generate key mechanistic insights into the overall metabolic and functional phenotypes. The Core phenotyping services include:

  • High-throughput and multiplexed measurement of serum/tissue/cell culture levels of hormones, cytokines, and chemokines using Luminex multiplexing technology
  • High-throughput multiplexed measurement of blood/tissue/urine levels of metabolites and electrolytes using Cobas Clinical Chemistry Analyzer
  • Complex molecular analysis of intracellular signaling pathways associated with insulin action, glucose and lipid metabolism, and inflammation.
  • Ultra-sensitive single-plex ELISA measurements of difficult to detect analytes or those not available in multiplexed format.

 

DIRECTOR

Randall H. Friedline, Ph.D.

Instructor of Molecular Medicine
Albert Sherman Center, 9th Floor, Suite 1016
Phone: (508) 856-8791 
randall.friedline@umassmed.edu

Randall Friedline

CORE STAFF

Xiaodi Hu, M.S.
Lab Manager
Albert Sherman Center, 9th Floor, Suite 1016
Phone: (508) 856-4312 (phone)
xiaodi.hu@umassmed.edu

Xiaodi Hu Lab

Address:

University of Massachusetts Medical School
368 Plantation Street
Albert Sherman Center, 9th Floor, Suite 1015-1016
Worcester, MA 01605

 
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