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This patient experienced
a typical episode of transient monocular blindness (amaurosis
fugax). Many patients describe a blackout, a cloud or
a "gray fog" that obscures vision in one eye, or in part of one
eye. Occasionally it may be likened to "a shade falling over the
eye." Usually the attacks are very brief, lasting about 1- 5 minutes,
and are followed by full restoration of vision. Some patients
have many repeated attacks, but others have only one or a few.
Two major mechanisms
are proposed to explain this type of TIA. (1) A tiny
piece of thrombus formed on an ulcerated plaque at or near the
carotid bifurcation, or a piece of the underlying plaque itself,
breaks off and enters the ophthalamic artery and finally lodges
in a retinal arteriole. Ophthalmoscopic observation of the
retinal vessels during actual episodes of transient monocular
blindness has shown bits of whitish material (small emboli) temporarily
blocking the retinal arteries. (2) A low perfusion
state resulting from ICA
stenosis (and probably temporary formation of thrombus that
further blocks the vessel) causes regions far from the site of
stenosis (like the retina) to become briefly ischemic.
There can be a number
of reasons for a transient loss of vision in one eye, such as
inflammation of the arteries that supply the eye. However,
in older patients the cause is often carotid occlusive disease,
produced by significant atherosclerosis
and plaque erosion in the extracranial carotid. In such
a patient, transient monocular blindness may be a warning that
a stroke is in the offing. Patients like this should therefore
be evaluated immediately.