RNA Therapeutics Institute Faculty

RTI Bullet Victor Ambros, PH.D.


Silverman Professor of Natural Sciences, Professor Program in Molecular Medicine, Co-Director RNA Therapeutics Institute


Focus:
Molecular and genetic control of animal development;microRNA regulatory mechanisms.

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RTI Bullet Neil Aronin, M.D.


Professor, Department of Medicine


Focus:
Pathogenesis of neurodegenerative diseases, especially Parkinson's disease and Huntington's disease.

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RTI Bullet David Grunwald, PH.D.


Assistant Professor, Biochemistry and Molecular Pharmacology


Focus:
The interface between microscopy development and (nuclear) cell biology, with a strong focus on the travels of mRNA and nucleocytoplasmic transport.

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RTI Bullet Anastasia Khvorova, Ph.D.


Professor, Program in Molecular Medicine


Focus:
Development of novel oligonucleotide-based therapeutics, drug development. Mechanism of small RNA trafficing, RNA medicinal chemistry and delivery.

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RTI Bullet Andrei Korostelev, PH.D.


Assistant Professor, Biochemistry and Molecular Pharmacology


Focus:
Structure and function of ribosome.

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RTI Bullet Craig Mello, PH.D.


Investigator Howard Hughes Medical Institute, Blais Chair of Molecular Medicine, Professor Program in Molecular Medicine, Co-Director RNA Therapeutics Institute


Focus:
Investigation of the mechanism of RNA interference; investigation of how embryonic cells differentiate and communicate during development.

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RTI Bullet Melissa J. Moore, PH.D.


Investigator Howard Hughes Medical Institute, Eleanor Eustis Farrington Chair in Cancer Research, Professor Biochemistry and Molecular Pharmacology, Co-Director RNA Therapeutics Institute


Focus:
Post-transcriptional gene regulation in eukaryotes via mechanisms involving RNA.

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RTI Bullet Phillip Zamore, PH.D.


Investigator Howard Hughes Medical Institute, Gretchen Stone Cook Professor of Biomedical Sciences, Professor Biochemistry and Molecular Pharmacology, Co-Director RNA Therapeutics Institute


Focus:
Dissecting the RNAi and miRNA pathways.

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RTI Research Faculty


 
 
 Darryl Conte, PH.D.

RTI Bullet Darryl Conte, PH.D.


Research Assistant Professor, RNA Therapeutics Institute



 

RTI Affiliated Faculty


RTI Bullet Robert Brown, M.D.


Professor and Chair, Department of Neurology


Focus:
Neuromuscular diseases including amyotrophic lateral sclerosis (ALS, also known as Lou Gehrig's disease), muscular dystrophy, adrenoleukodystrophy, hereditary neuropathy and hyperkalemic periodic paralysis.

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RTI Bullet Vivian Budnik, Ph.D.


Professor, Neurobiology


Focus:
Molecular Mechanisms of Synapse Assembly and Plasticity

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RTI Bullet Michael P. Czech, Ph.D.


Professor and Chair, Program in Molecular Medicine


Focus:
RNAi-based therapeutic strategies for inflammatory and metabolic diseases.

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RTI Bullet Jane E. Freedman, M.D.


Director, Translational Research, UMass Memorial Heart & Vascular Center,
Professor, Department of Medicine


Focus:
Immunity, inflamation and circulation transcripts in atherothrombotic disease in a basic and high-throughput laboratory.

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RTI Bullet Terence Flotte, M.D.


Dean School of Medicine, Provost and Executive Deputy Chancellor, Professor, Pediatrics


Focus:
Recombinant adeno-associated virus (AAV) gene therapy vectors for, cystic fibrosis (CF), alpha-1-antitrypsin deficiency (AAT) and fatty oxidation disorders (FAO)
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RTI Bullet Fen-Biao Gao, Ph.D.


Professor, Neurology


Focus:
Understanding frontotemporal dementia and neuronal microRNAs.

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RTI Bullet Guangping Gao, Ph.D.


Professor Department of Microbiology and Physiological Systems, Director Gene Therapy Center & Vector Core, Scientific Director UMMS-China Translational Research Initiatives


Focus:
Adeno-associated virus (AAV) vector mediated gene transfer for gene therapy & gene therapy of inherited neurodegenerative Canavan Disease.

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RTI Bullet Michael Green, Ph.D., M.D.


Professor and Director, Program in Gene Function and Expression, Professor Program in Molecular Medicine


Focus:
Eukaryotic gene regulation and cancer molecular biology.

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RTI Bullet Gang Han, Ph.D.


Assistant Professor, Biochemistry and Molecular Pharmacology


Focus:
Synthetic nanomaterials for siRNA delivery and biomolecule imaging.

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RTI Bullet Allan Jacobson, Ph.D.


Professor and Chair, Department of Microbiology and Physiological Systems


Focus:
Cytoplasmic Aspects of the Post-transcriptional Regulation of Gene Expression.

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RTI Bullet Nathan Lawson, Ph.D.


Associate Professor, Program in Molecular Medicine


Focus:
Role of non-coding RNA's in vascular development and disease.

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RTI Bullet Jeremy Luban, M.D.


David L. Freelander Memorial Professor in HIV/AIDS Research, Professor in Molecular Medicine


Focus:
HIV-1 replication, pathogenesis, and immunity.

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Rene Maehr

RTI Bullet Rene Maehr, Ph.D.


Assistant Professor, Program in Molecular Medicine


Focus:
Pluripotent stem cell-based models of immune deficiencies and autoimmunity.

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RTI Bullet Gary Ostroff, Ph.D.


Research Professor, Program in Molecular Medicine


Focus:
Nanomaterial science to develop delivery technology targeting chronic diseases.

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RTI Bullet Joel Richter, Ph.D.


Professor, Program in Molecular Medicine


Focus:
Translational Control of Meiosos, Mitosos, and Neuronal Synaptic Platicity.

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RTI Bullet Sean Ryder, Ph.D.


Associate Professor, Biochemistry and Molecular Pharmacology


Focus:
RNA-binding proteins in development and disease.

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RTI Bullet William Theurkauf, Ph.D.


Professor, Program in Molecular Medicine


Focus:
Eukaryotic gene regulation and cancer molecular biology.

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RTI Bullet Zuoshang Xu, M.D., Ph.D.


Professor, Biochemistry and Molecular Pharmacology


Focus:
Mechanism and Therapy of Neurodegenerative Diseases.

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