Registry Access

button browsebutton geneticliterature searchAdd new data

Current Stem Cell News

Experiments prove 'stemness' of individual immune memory cells
Specific individual immune cells, termed 'central memory T cells,' have all the essential characteristics of adult tissue stem cells, researchers have proven for the first time. Such cells can perpetuate themselves indefinitely and generate diverse offspring that can reconstitute "tissue" function. These findings indicate that it should be possible to fully restore specific immunity to pathogens in immunocompromised patients by substitution of small numbers of these T cells.
3-D-printed tissues advance stem cell research
A tissue engineering and vascular biology expert recently won a Faculty Early Career Development Award for his work on 3D tissue printing, and its contribution of the advancement of stem cell research.
New technique maps life's effects on our DNA: Powerful single-cell technique to study environmental effects on DNA
Researchers have developed a powerful new single-cell technique to help investigate how the environment affects our development and the traits we inherit from our parents.
'Support' cells in brain play important role in Down syndrome
A group of cells in the brain has been identified by researchers who say that it plays an important role in the abnormal neuron development in Down syndrome. After developing a new model for studying the syndrome using patient-derived stem cells, the scientists also found that applying an inexpensive antibiotic to the cells appears to correct many abnormalities in the interaction between the cells and developing neurons.
Discovery may make it easier to develop life-saving stem cells
Not unlike looking for the proverbial needle in a haystack, a team of researchers has found a gene that could be key to the development of stem cells -- cells that can potentially save millions of lives by morphing into practically any cell in the body. The gene, known as ASF1A, is at least one of the genes responsible for the mechanism of cellular reprogramming, a phenomenon that can turn one cell type into another, which is key to the making of stem cells.
Gene that links stem cells, aging, cancer discovered by researchers
An organism is healthy thanks to a good maintenance system: the normal functioning of organs and environmental exposure cause damage to tissues, which need to be continuously repaired. This process is not yet well understood, but it is known that stem cells in the organs play a key role. Researchers have now discovered one of the key genes that make up the maintenance mechanism for tissues.
Gene profiling technique to accelerate stem cell therapies for eye diseases
A technique that will speed up the production of stem-cell derived tissues has been developed by researchers. The technique will help the researchers in their efforts to use patients’ skin cells to regenerate retinal pigment epithelium (RPE) -— a tissue in the back of the eye that is affected in several blinding eye diseases. It will also help the scientists search for drugs for personalized treatments.
Obesity may be impacted by stress, study shows
A new study shows that stress may play a role in the development of obesity. Using experimental models, researchers showed that adenosine, a metabolite released when the body is under stress or during an inflammatory response, stops the process of adipogenesis, when adipose stem cells differentiate into adult fat cells.
Genetic recipe to turn stem cells to blood
The ability to reliably and safely make in the laboratory all of the different types of cells in human blood is one key step closer to reality. Stem cell researchers have discovered two genetic programs responsible for taking blank-slate stem cells and turning them into both red and the array of white cells that make up human blood.
Opening-up the stem cell niche: Hematopoietic stem cell transplantation without irradiation
A novel mouse model allows for the transplantation of human blood-forming stem cells without the need for irradiation therapy. The results show that the Kit receptor is important for the function of human blood stem cells, notably in a transplantation setting. Further studies will now focus on using this knowledge about the role of the receptor to improve conditioning therapy in the setting of therapeutic hematopoietic stem cell transplantation in patients.

Our collaborators:

Stembook Link