Department of Medicine

Rheumatology Division

Research

Bonnie J. Bidinger, MD Assistant Professor of Medicine

Bidinger B., Torres R., Rossetti R.G., Brown L., Beltre R., Burstein S., Lian J.B., Stein G.S., Zurier R.B. Ajulemic acid, a nonpsychoactive cannabinoid acid, induces apoptosis in human T lymphocytes.   Clinical Immunology. 2003; 108:95-102. 

Zurier R.B., Rossetti R.G., Burstein S.H., Bidinger B.  Suppression of human monocyte interleukin-1ß production by ajulemic acid, a nonpsychoactive cannabinoid.   Biochemical Pharmacology. 2003; 65:649-655. 
Ellen Gravallese, MD Professor of Medicine 

Pathogenic mechanisms of inflammatory arthritis, with a special interest in rheumatoid arthritis. 

Identification of cell types producing matrix metalloproteinase enzymes that destroy the extracellular matrix of cartilage in disease such as rheumatoid arthritis and pigmented villonodular synovitis, and the identification of pathways leading to bone destruction in rheumatoid arthritis.  

Focal bone erosions in rheumatoid arthritis and the relationship of articular and systemic bone loss.  
Leslie R. Harrold, MD, MPH Associate Professor of Medicine 

Harrold LR, Yood RA, Mikuls TR, Andrade SE, Davis J, Fuller J, Chan KA, Roblin D, Raebel MA, Von Worley A, Platt R, Saag K.  Sex differences in gout epidemiology, evaluation and treatment.   Annals of Rheumatic Disease (in press). 

Harrold LR, Saag KG, Yood RA, Mikuls TR, Andrade SE, Fouayzi H, Davis J, Chan KA, Raebel MA, Von Worley A, Platt R.  Validity of gout diagnoses in administrative data.   Arthritis Care and Research (in press). 
Judith A. Stebulis, MD Assistant Professor of Medicine 

Mechanisms whereby nonpsychoactive antiinflammatory cannabinoid acids exert their effects. 
Robert B. Zurier, MD Professor of Medicine 

Mechanisms of joint tissue injury. 

Exploration of influence of nonpsychoactive cannabinoid acids on immune/inflammatory reactions.