Center for Psychopharmacologic Research

And Treatment in the News.....

   
February 3, 2012

New hope for treatment-resistant depression

Small pulses sent deep within the brain show great promise

By Sandra Gray
UMass Medical School Communications

 Dr. Rothschild is now leading a clinical trial at UMass Medical School and UMass Memorial Medical Center for Deep Brain Stimulation (DBS), a state-of-the-art approach that has shown great promise in previous small studies of patients suffering from treatment-resistant depression.  See UMassMedNow at www.umassmed.edu/news
January 19, 2012

Antidepressant expert creates user-friendly book
Rothschild editor of ‘The Evidence-Based Guide to Antidepressant Medications’

By Sandra Gray
UMass Medical School Communications

Internationally renowned depression expert Anthony Rothschild, MD, the Irving S. and Betty Brudnick Endowed Chair in Psychiatry and professor of psychiatry, has created a user-friendly text that digests the current research into best practices with antidepressants...for more information please see http://www.umassmed.edu/news/2012/research/rothschild_antidepressant_book.aspx

December 9, 2011
Just Published!
appi.org
The Evidence-Based Guide to Antidepressant Medications

Edited by Anthony J. Rothschild, M.D.

This second book in the Evidence-Based Guides series provides a clear reference to the current knowledge and evidence base for the use of antidepressants among a variety of patients across a wide range of disorders.

Chapters within this guide are authored by experts in their respective areas of practice, and synthesize a large amount of medical literature into a comprehensive, yet understandable, concise, reader-friendly guide.

Each chapter covers both the FDA-approved and off-label use of antidepressant medications and the evidence base for their use. Each chapter also features useful tables pertaining to specific topics, such as summaries of uses and efficacy, and important clinical pearls of wisdom in the Key Clinical Concepts.

2012 • 480 pages • ISBN 978-1-58562-405-8 • Paperback
$69.00 • Item #62405

BUY NOW!

November 23, 2011

Psychiatric News Update

From the experts...

Do Antidepressants Cause Suicide?

Anthony J. Rothschild

In this article, I provide a brief outline of the discussion of two timely topics: whether antidepressants "really work" and whether antidepressants "can cause suicide".

>>read more


Reuters Health

October 4, 2011

Wendy Marsh MD MS and her co-authors awarded a top 2011 Poster Prize at the 22nd Annual North American Menopause Society (NAMS) Meeting in Washington DC, Sep. 24. Using the SWAN (Study of Women's health Across the Nation) database, Dr. Marsh and colleagues' study found that a longer duration of estradiol exposure, measured by years from menarche to menopause, prior to entering the menopausal transition was protective against depression during the menopausal transition. Read what Dr. Marsh says in the Reuters Health article, Oct. 4.


August 2011

Efforts to fight depression earn national recognition
Center of Excellence advances collaborative work in prevention, treatment and advocacy 

UMass Medical School and clinical partner UMass Memorial Health Care have been invited to join the National Network of Depression Centers (NNDC) as a Center of Excellence.

An elite network comprising 22 academic medical institutions, the NNDC was founded in 2007 to advance comprehensive, multidisciplinary collaboration and networking of resources on a national scale. “Our acceptance into this network of prestigious institutions is recognition of the collaborative work in the areas of depression treatment, research and advocacy underway at UMass Medical School and UMass Memorial,” said Anthony Rothschild, MD, the Irving S. and Betty Brudnick Chair in Psychiatry and professor of psychiatry.

For more information go to 

http://www.umassmed.edu/news/community/2011/efforts-to-fight-depression-recognized.aspx


July 14, 2011

Research Could Pinpoint Postpartum Depression Risks
By Sera Congi, WBZ-TV

June 22, 2011
Study uses brain imaging to understand postpartum depression
Findings may help identify women who are at high risk 

“Using new methods of imaging and measuring the brain’s chemistry, we can look at specific neurotransmitters in the brain involved in depression and see if there are any differences between women who develop postpartum depression and those who don’t,” said Kristina Deligiannidis, MD, assistant professor of psychiatry and principal investigator on the study.

For the full article and video please see:
For more information on Dr. Deligiannidis's research please see:

May 11, 2011

66th SOBP Annual Meeting

Dr. Kristina Deligiannidis recently returned from San Francisco where she received a Society of Biological Psychiatry (SOBP) Travel Fellowship Award to attend the 66th SOBP Annual Meeting, President's reception (Helen Mayberg, MD) and an Awards Reception.

Six junior investigators in biological psychiatry research were awarded from the US, and six were awarded internationally to receive this fellowship award.

https://www.sobp.org/i4a/pages/index.cfm?pageID=1

 

Dr.D at the SOBP
Trey Sunderland, MD (SOBP Executive Secretary), Kristina Deligiannidis, MD and Elliott Richelson, MD (SOBP Treasurer).

 


May 1, 2011

2010 Pilot Project Program Awardee

Principal Investigator 
Kristina Deligiannidis, MD (T1)

A Neuroendocrine and Neurochemical Biosignature in Late Pregnancy and its Association with the Development of Postpartum Depression in Women

 

 

 

 

The World Health Organization reports that depression is the leading cause of disease burden and years loss to disability for women in their childbearing years(1). The perinatal (i.e. antenatal and postpartum) period is a time of elevated risk for depression; approximately 1 in 8 women are diagnosed with postpartum depression (PPD) annually. PPD is marked by feelings of hopelessness, suicidal ideation, guilty ruminations, loss of interest and energy, loss of appetite, dysregulated sleep and poor daily functioning.  To read more please see http://www.umassmed.edu/Content.aspx?id=126098.    


April 1, 2011
 
UMass Memorial congratulates its physicians named to the 2011 list of

Best Doctors 2011

Including: Department of Psychiatry's Anthony J. Rothschild MD

Best Doctors®, Inc. continuously surveys specialists worldwide to ask which doctors they would choose for treatment in their own specialty. Less than five percent of U.S. doctors are named to the list. UMass Memorial Health Care is proud that more than 10 percent of our doctors at our five hospitals were named to this prestigious list


March 15, 2011
Be Mentally Well Program
Depression experts offer hope
UMMS psychiatrists shed light on pervasive but treatable medical condition

By Sandra Gray
UMass Medical School Communications
March 23, 2011

 

Launched last fall, Be Mentally Well is a series of informational lectures that are free and open to the public. At “Understanding and Treating Depression,” UMMS psychiatrists Anthony Rothschild, MD, Gary Moak, MD, and Kristina Deligiannidis, MD, clarified the signs and symptoms of depression, discussed the great variety of effective treatments already available and those under development, and explained the exceptional challenges of recognizing and treating depression in the elderly. 

For more on this article please visit:
http://www.umassmed.edu/news/community/2011/hope_for_depression.aspx

To find out when “Understanding and Treating Depression” will be broadcast by Worcester local access cable station WCAA-TV13, visit their website at http://www.wccatv.com/schedule.    


February 2011

EXPERT’S CORNER: Winter’s dark makes some especially SAD

According to Assistant Professor of Psychiatry Kristina Deligiannidis, MD, while genetic predisposition and preexisting depressive disorders can contribute to SAD, it is widely believed to result from the decrease in natural sunlight that occurs during the winter months, with the greatest incidence in northerly climes like ours.

see video: http://www.umassmed.edu/news/articles/2011/SAD.aspx


October 13, 2010  

Women’s mental health focus of sixth annual Psychiatry Research Day

Dr. Kristina Deligiannidis discusses her research   Anthony Rothschild, Research Day 10.13.2010
 Dr. Kristina Deligiannidis discusses her research
into gender differences in mood disorders at the Psychiatry Research Day poster session with
Robert J. Carey Jr., PhD, assistant professor
of psychiatry, while research coordinator,
Chelsea Kosma looks on.
 

Among many distinguished guests at the event were Betty Brudnick and Shirley Siff, EdD, who
with their husbands have both endowed chairs
in psychiatry. The Irving S. and Betty Brudnick
Chair in Psychiatry is held by Anthony Rothschild pictured above.

 
 
August 11, 2010
Dr. Rothschild was recently interviewed for articles appearing on:
 
WebMD: Better Information. Better Health.    

June 17, 2010

WFBR grants fund innovative research

The latest round of Worcester Foundation for Biomedical Science (WFBR) Annual Research Grants, awarded to 13 UMass Medical School investigators, is continuing the tradition of sowing seeds for innovative research across a broad array of disciplines.

WFBR Annual Research Grants allow recipients to produce preliminary data needed to secure grants from the National Institutes of Health. Among the projects funded this year with $35,000 in seed grants are those of Kristina Deligiannidis, MD, assistant professor of psychiatry; Jeffrey Jensen, PhD, assistant professor of bioinformatics & integrated biology and molecular medicine; and Laura Lambert, MD, assistant professor of surgery.

Dr. Deligiannidis’s lab will obtain pilot data to establish a neurochemical biosignature (or marker) to identify pregnant women at risk for developing post-partum depression (PPD), a disorder which afflicts one in eight new mothers, so that a potential screening test may be developed. To investigate emerging pre-clinical and clinical evidence suggesting that dysregulation of neuroactive steroids and interrelated neurochemical systems contribute to the development of PPD, her lab will analyze blood levels of neuroactive steroids during and post pregnancy. In addition, they will measure women’s brain levels of specific neurochemicals that have been implicated in the development of PPD with magnetic resonance spectroscopy, a sophisticated neuroimaging technique. A School of Medicine and UMMS psychiatry residency graduate, Deligiannidis recently joined the faculty and is the medical director of the
Depression Specialty Clinic at UMass Memorial Medical Center.


May 4, 2010

Senior Scholars Day

Senior Scholars Day 2010 was held Monday, May 3rd in the Faculty Conference Room. Students presented their research posters from 11-12noon. Senior Scholars Day keynote speaker, Dr. Anthony Rothschild, spoke about his career in research following the poster session. Students individually recieved certificates for completing their research project.


2010 American Psychiatric Association Annual Meeting in New Orleans, LA
Saturday, May 22 – Wednesday, May 26
 
APPI Master Courses 

Psychopharmacologic, ECT, and Psychotherapeutic Treatment of Psychotic (Delusional) Depression
Monday, May 24 1:00pm-5:00pm
Presented by Anthony J. Rothschild, M.D.,with Brandon Guadiano, Ph.D.

This course will focus on how to accurately diagnose and assess patients with psychotic depression, identify the difficult differential diagnoses between psychotic depression and other psychiatric disorders, understand the use of adjunctive psychotherapy in patients with psychotic depression, and treat patients with psychotic depression with somatic therapies including medications or referral to electroconvulsive therapy.
The price includes a copy of
Clinical Manual for the Diagnosis and Treatment of Psychotic Depression.
 

Advances in the Use of Antipsychotic Medications
Tuesday, May 25 9:00am-12:00pm
Co-Chairpersons: Anthony J. Rothschild, M.D., Kristina Deligiannidis, M.D.

This session is based, and all the speakers are authors from, the recently published Evidence Based Guide To Antipsychotic Medications. Each speaker will review both FDA-approved and off-label uses of antipsychotic medications (both first generation and second generation) and the evidence base that supports (or does not support) their use. Each of the speakers has taken a large amount of medical literature and synthesized it into a comprehensive and understandable formfor the practicing clinician. This session will focus on the use of antipsychotic medications in schizophrenia, schizoaffective disorder, personality disorders, mood and anxiety disorders, and in the medically ill.


MARCH 22, 2010

KRISTINA DELIGIANNIDIS MD has been selected to participate in the 2010 Career Development Institute (CDI) for Psychiatry, a career enhancement opportunity that provides support around launching and maintaining a career in mental health research. 15-20 participants were chosen nationally to attend the CDI this year.


 UMass Memorial congratulates its physicians named to the 2010 list of

Best Doctors 2010

Including: Department of Psychiatry's Anthony J. Rothschild MD   

Best Doctors®, Inc. continuously surveys specialists worldwide to ask which doctors they would choose for treatment in their own specialty. Less than five percent of U.S. doctors are named to the list. UMass Memorial Health Care is proud that more than 10 percent of our doctors at our five hospitals were named to this prestigious list.


NOW AVAILABLE!

The Evidence-Based Guide to Antipsychotic Medications

Edited by Anthony J. Rothschild, M.D.

The Evidence-Based Guide to Antipsychotic Medications is designed to provide both clinicians and residents with focused, comprehensive, and clinically relevant information regarding the use of antipsychotic medications to treat a broad range of psychiatric conditions—from mood and anxiety disorders to substance abuse, personality disorders, and schizophrenia.

For more information visit: http:\\www.appi.org/book.cfm?id=62366


AlSO AVAILABLE @ APPI!

Clinical Manual for Diagnosis and Treatment of Psychotic Depression

Anthony J. Rothschild, M.D.

Psychotic depression is a dangerous and debilitating illness that, tragically, often has fatal consequences. Studies indicate that between 16% and 54% of all depressed adults suffer from a psychosis. While this condition is completely treatable, thousands of cases remain misdiagnosed or overlooked because of a lack of interest and awareness among clinicians, the pharmaceutical industry, and the National Institute of Mental Health. As the first comprehensive guide to cover assessment, treatment, and management of patients with psychotic depression, Clinical Manual for Diagnosis and Treatment of Psychotic Depression, by Dr. Anthony Rothschild, is an invaluable resource for both clinicians and students. 

Psychotic Depression book review

For more information visit: http://www.appi.org/book.cfm?id=62292