About Us
My laboratory was established in 1989 with a grant from the W.M. Keck Foundation given to the former Worcester Foundation for Biomedical Research. One of the primary focuses of my lab is to utilize state-of-the-art methodologies and instrumentation to characterize proteins of biological interest for investigators around the world. The laboratory continues to gain national recognition as gauged by the numerous protein samples that are sent from both corporate and academic laboratories throughout the country.
The lab is equipped with the latest instrumentation for protein/peptide mass spectral analysis. Our equipment includes a Shimadzu Biotech Axima TOF2 (Matrix Assisted Laser Desorption tandemTime -of-Flight (MALDI-TOF-TOF) mass spectrometer, and Axima QIT ( Quadrupole Ion Trap Matrix Assisted Laser Desorption Time-of-Flight (MALDI-QIT-TOF) mass spectrometer. In .jpg "John Lesyk")
addition to this we have a Finnigan Electrospray LCQ Deca Ion Trap mass spectrometer (ESI LC/MS/MS)
John Leszyk, Ph.D., Director
Clarkson University Ph.D. 1988
SUNY at Oswego, B.S. 1984
Often times one spends several weeks in the preparation of a protein sample for analysis. This analysis may involve identification of the protein or characterization of chemical or post-translational modifications. The way the sample is prepared is crucial to the types of techniques that can be employed and the success in characterization. One of the goals of this web site is to educate you on the technology employed and to advise you on your sample preparation so as to optimize your chances of success. Depending on the techniques employed for characterization I will assist you in data evaluation and interpretation so that you are comfortable with the information and can further pursue your projects.