SERVICES AVAILABLE

1. PROTEOMICS

Established methods include
• MW determination and sample purity analysis by MALDI
• Gel band protein ID by MALDI-TOF and nanoscale HPLC/MS/MS
• MudPIT for identification of large numbers of proteins in complex biological mixtures
• ITRAQ and ICAT for quantitation of large numbers of proteins in complex mixtures
• Location of phosphorylation and other posttranslationally modified sites
• Location of disulfide bonds
• Quantitation of isodipeptide cross-linking
• Techniques for determination protein confirmation by H/D exchange.

2. SMALL MOLECULES
• Lipidomics
• Metabolomics
• Pharmacokinetics (stable isotope steady-state and non-steady state)

To schedule instrument time, please call the lab at 508-856-8111.