Section: Rotations

Heidi Tissenbaum, Ph.D.

Academic Role: Associate Professor

Faculty Appointment(s) In:
   Program in Gene Function and Expression
   Program in Molecular Medicine

Other Affiliation(s):
   Interdisciplinary Graduate Program

Potential Rotation Projects

Project #1: Genetic screen to identify genes that act in the sir-2.1 pathway that regulates aging.

Project #2: Identify new genes that affect aging by gene dosage.

Project #3: Create mutations in the C. elegans homologs of genes known to regulate insulin signaling in humans and determine their affects on life span.

Overall questions of the lab:

1. Are the general mechanisms of life span conserved? How?



2. How can we control the genes that affect life span?



3. Is aging the sums of many processes or are there specific signaling pathways for aging?



4. How does life span regulation relate to insulin signaling?

Program Affiliations:

Gene Function and Expression, Interdisciplinary Graduate Program

Office: 621
Phone: 508-856-5840
E-mail: Heidi.Tissenbaum@umassmed.edu
Keywords: Organisms - C. elegans, Cancer Biology, Diabetes, Aging, Genetics

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