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Leslie Berg, Ph.D.
Academic Role: Professor
Faculty Appointment(s) In:
Pathology
Other Affiliation(s):
Biochemistry and Molecular Pharmacology
Center for AIDS Research
Interdisciplinary Graduate Program
Program in Immunology and Virology
Representative Publications
Thomis, D.C., C.B. Gurniak, E. Tivol, A.H. Sharpe, and L.J. Berg. (1995). Defects in B lymphocyte maturation and T lymphocyte activation in mice lacking JAK3, Science 270, 794-797.
Andreotti, A. H., S. C. Bunnell, S. Feng, L. J. Berg and S. L. Schreiber. (1997). Intramolecular association of two domains in a Tec family tyrosine kinase influences binding of signaling proteins, Nature 384, 93-97.
Thomis, D.C. and L.J. Berg. (1997). Peripheral expression of JAK3 is required to maintain T lymphocyte function. J. Exp. Med. 185, 197-206.
Liu, K.-Q., S.C. Bunnell, C.B. Gurniak, and L.J. Berg. (1998). TCR-initiated calcium release is uncoupled from capacitative calcium entry in Itk-deficient T cells, J. Exp. Med. 187, 1721-1727
Bunnell, S.C., M. Diehn, M.B. Yaffe, P.R. Findell, L.C. Cantley, and L.J. Berg. (2000). Biochemical interactions integrating Itk with the TCR-initiated signaling cascade, J. Biol. Chem. 275:2219-2230.
Gozalo-Sanmillan, S., J.M. McNally, M.Y. Lin, C. Chambers, and L.J. Berg. (2001). Cutting Edge: Two distinct mechanisms lead to impaired T cell homeostasis in Jak3- and CTLA4-deficient mice. J. Immunol. 166, 727-730.
Miller, A.T. and L.J. Berg. (2002). Defective FasL expression and activation-induced cell death in the absence of Itk, J. Immunol., in press.
Office: S3-143B
Phone: 508-856-8371
E-mail: Leslie.Berg@umassmed.edu
Keywords:
Genetic Systems,
Signal Transduction,
Immunology
Postdoctoral Position Available
A postdoctoral position is available to study in this laboratory.
Contact Dr. Berg for additional details.
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