January 28, 2002

Worcester, Mass. - Two University of Massachusetts Medical School faculty were recently listed among the world's most highly cited scientists by the Institute for Scientific Information (ISI). Professors of Molecular Medicine Roger J. Davis, PhD, and Michael R. Green, MD, PhD, two Howard Hughes Medical Institute Investigators at UMMS, were featured on the Biochemistry and Biology listing, newly created by the Institute to showcase some of the most influential international scientific investigators. is a Web-based index that allows scientists to search for information on authors by name, research category, country or institutional affiliation, offering access to information about key contributors to science and technology during the period from 1981-1999. Once complete, the database will include the publication and achievement records of 250 pre-eminent researchers in 21 categories, including life sciences, medicine, physical sciences, engineering and social sciences.

Davis conducts groundbreaking research on the body's responses to changes in the environment at the cellular level, and the implications of those responses for a wide array of diseases. He and his colleagues were the first to identify and molecularly clone a particular set of genes called the JNK signal transduction pathway that plays an integral role in one cellular response to stress-apoptosis or "cell suicide."

Davis joined the medical school's faculty in 1985. Prior to that, he served as the Damon Runyon/Walter Winchell Cancer Fund Fellow at UMMS in the lab of Michael Czech, PhD, who is currently professor and chair of molecular medicine. Davis graduated from Queens' College of Cambridge University, Great Britain, where he received a bachelor's degree in natural sciences, advanced degrees in biochemistry and natural sciences, and a doctoral degree in biochemistry. He also was a research fellow at Queens' College.

Previously identified by the ISI as publishing the world's most cited research papers in 1995 and 1996, Davis said of the honor, "I am pleased to receive recognition that acknowledges the dedication and accomplishments of the students, research assistants, and post-doctoral fellows in my research group."

Green, the director of UMMS' Program in Gene Function & Expression, has also been recognized on the Genetics and Cell Biology listing. Green studies a variety of subjects relating to the regulation of gene expression in eukaryotic cells. His lab's investigations include the varied study of mRNA, a class of ribonucleic acid that carries the genetic code from the chromosome in the nucleus to the ribosome in the cytoplasm.

Green joined the medical school's faculty in 1990. He graduated with a bachelor's degree in biochemistry from the University of Wisconsin at Madison and earned his MD and PhD from Washington University in St. Louis. He completed his postgraduate training, including a fellowship, at Harvard University, and joined the faculty there in 1983.

The University of Massachusetts Medical School, one of the fastest growing academic health centers in the country, has built a reputation as a world-class research institution, consistently producing noteworthy advances in clinical and basic research. The Medical School attracts more than $123 million in research funding annually, 80 percent of which comes from federal funding sources. Research funding enables UMMS scientists to explore human disease from the molecular level to large-scale clinical trials. Basic and clinical research leads to new approaches for diagnosis, treatment and prevention of disease.

Alison Duffy, 508-856-2000

Related Links:
Biochemistry and Biology This link goes to an external web site

Howard Hughes Medical Institute This link goes to an external web site