Boston Globe: Mello’s RNAi discovery propelling new advancements against disease

By Lisa M. Larson

UMass Medical School Communications

February 24, 2014

Craig C. Mello, PhD (left) and Phillip D. Zamore, PhD

The discovery of RNA interference, the breakthrough that earned UMass Medical School’s Craig C. Mello, PhD, and Stanford University’s Andrew Z. Fire, PhD, the Nobel Prize in Medicine in 2006, is fueling significant progress for some local biotech companies who are using it to fight diseases, according to a story in the Feb. 24 Boston Globe.

Phillip D. Zamore, PhD, Howard Hughes Medical Institute Investigator, the Gretchen Stone Cook Chair of Biomedical Sciences, and professor of biochemistry & molecular pharmacology, explained in the article how scientists have developed the technology to advance the field. Dr. Zamore is a founding member of biotech firm Alnylam Pharmaceuticals Inc., which recently signed a large development deal with Genzyme Corp.

Dr. Mello is a Howard Hughes Medical Institute Investigator, the Blais University Chair in Molecular Medicine and distinguished professor of molecular medicine and cell biology.

Read the full story at: RNAi tactic to fight disease offers new hope