Breakthrough garners worldwide coverage

By Lisa M. Larson

UMass Medical School Communications

July 18, 2013

Media outlets around the globe are reporting on the innovative UMass Medical School discovery into Down syndrome, in which Professor Jeanne Lawrence, PhD, and colleagues were able to silence the extra chromosome that causes disabilities in people with Down syndrome. The research, conducted in cell cultures and reported in the current issue of the journal Nature, is “revolutionary,” scientists say.

“It really is revolutionary, in terms of causing us all to rethink the one impossible thought—can you make, functionally, that extra chromosome disappear,” Dr. Brian Skotko, co-director of the Down Syndrome Program at Massachusetts General Hospital, said in a front page Boston Globe story. “I don’t think any of us thought it was possible or even within the current realm of scientific dreaming.”

Here are some of the media stories on the development today.

Scientists hit at core of Down syndrome
Boston Globe

Fresh Insights Into Down Syndrome
WBUR’s Radio Boston

New Genetic Therapy Could Erase Down Syndrome
WBUR’s Here & Now

UMass Medical Researchers Block Down Syndrome Chromosome (video)
Fox 25 Morning News

UMass researchers block Down syndrome chromosome (video)
WCVB Channel 5

Stem cell research yields Down syndrome breakthrough
Boston Herald

Scientists find way to silence extra chromosome that causes Down syndrome
Fox News

Down Syndrome’s Extra Chromosome Silenced in Lab Cells


Scientists "Switch Off" Down's Syndrome's Extra Chromosome in a Lab
Nature World News

Genetic advance in Down syndrome
BBC News

Phenomena: Not Exactly Rocket Science
National Geographic

Technique inactivates Down-causing chromosome
Science News

Scientists figure out how to turn off Down syndrome in laboratory
CBS News

Scientists find way to silence extra chromosome that causes Down syndrome, could lead to new therapies
New York Post

Down's syndrome cells 'fixed' in first step towards chromosome therapy
The Guardian

Chromosome for Down's Is Switched Off
Discovery News

UMass researchers 'shut down' trigger for Down syndrome
Boston Business Journal