2015 Top Story

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New strategy will allow scientists to map regulatory networks associated with complex multi-gene diseases

New strategy will allow scientists to map regulatory networks associated with complex multi-gene diseases

Scientists in the lab of Marian Walhout, PhD, have applied a powerful tool in a new way to characterize genetic variants associated with human disease that will allow researchers to more easily and efficiently describe genomic variations underlying complex, multi-gene diseases.

Expert’s Corner: Mitchell Sokoloff, MD, recommends PSA screening

Expert’s Corner: Mitchell Sokoloff, MD, recommends PSA screening

Mitchell Sokoloff, MD, discusses the controversy surrounding prostate-specific antigen (PSA)-based screening recommendations in this Expert’s Corner video.

Neuroscientists identify brain circuitry responsible for increased anxiety in smokers trying to quit

Neuroscientists identify brain circuitry responsible for increased anxiety in smokers trying to quit

In a promising breakthrough for smokers who are trying to quit, neuroscientists at UMass Medical School and The Scripps Research Institute have identified novel circuitry in the brain responsible for anxiety commonly experienced during withdrawal from nicotine addiction.

Pilot clinical study at UMMS to test ‘Sugar’ diabetes app

Pilot clinical study at UMMS to test ‘Sugar’ diabetes app

An advanced smartphone application developed at Worcester Polytechnic Institute to help people with diabetes better manage their weight and blood sugar level and assess the status of chronic foot ulcers, is entering a pilot clinical study at UMass Medical School.

Editing HIV out of our genome with CRISPR

Editing HIV out of our genome with CRISPR

UMass Medical School researchers are using CRISPR/Cas9, a powerful gene editing tool, to develop a novel technology that can potentially cut the DNA of the latent HIV virus out of an infected cell.

Sequencing the intestinal microbiome to target therapies

Sequencing the intestinal microbiome to target therapies

Vanni Bucci, PhD, from UMass Dartmouth, is collaborating with colleagues in the UMass Center for Microbiome Research to sequence the intestinal microbiome with the goal of targeting treatments for specific enteric diseases and prototyping probiotic cocktails that could be used as a substitute for antibiotic treatment.

Searching the microbiome for clues to managing inflammatory bowel disease

Searching the microbiome for clues to managing inflammatory bowel disease

Based on the success of the Inflammatory Bowel Disease Anti-Inflammatory Diet, Barbara Olendzki is collaborating with colleagues in the UMass Center for Microbiome Research to uncover how exactly this diet affects gut bacteria.

Solving the complex problem of recurrent C. diff with a simple solution

Solving the complex problem of recurrent C. diff with a simple solution

Fecal transplant, a novel therapy that Randy Pellish, MD, is exploring with his patients who have recurrent C. diff, is proving to be more than 90 percent effective.

Expert’s Corner: Roula Choueiri, MD, on detecting autism spectrum disorders

Expert’s Corner: Roula Choueiri, MD, on detecting autism spectrum disorders

Roula N. Choueiri, MD, associate professor of pediatrics, offers advice to parents and caregivers concerned that their child might have an autism spectrum disorder. 

UMMS students help children ACE Autism

UMMS students help children ACE Autism

Thanks to student volunteers from UMass Medical School, a special group of Central Massachusetts children have been provided an opportunity to learn to love tennis through the ACEing Autism program.

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