2016 Top Story

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UMMS-led discovery of ALS gene funded by Ice Bucket Challenge; nets global attention

UMMS-led discovery of ALS gene funded by Ice Bucket Challenge; nets global attention

The discovery of a new gene implicated in ALS, led by UMMS scientist Jon Landers, PhD, and funded by The ALS Association with donations from the 2014 ALS Ice Bucket Challenge, has garnered extensive media coverage and validated the success of the social media phenomenon.

New gene variants present in 3 percent of all ALS patients

New gene variants present in 3 percent of all ALS patients

John Landers, PhD, led a team of more than 80 scientists who found that variations in a gene with multiple functions in neurons are present in approximately 3 percent of all cases of ALS in North American and European populations, both sporadic and familial.

UMMS researchers make ‘startling’ discovery that a Salmonella protein reduces drug resistance in tumors

UMMS researchers make ‘startling’ discovery that a Salmonella protein reduces drug resistance in tumors

Scientists at UMass Medical School have found that the Salmonella protein SipA naturally reduces a well-known drug-resistant molecule found in many different types of cancer cells. They collaborated to deploy a SipA ‘nanobug’ that rendered tumors ‘almost undetectable.’

Dekker, colleagues at Curie Institute untangle Barr body of inactive X chromosome

Dekker, colleagues at Curie Institute untangle Barr body of inactive X chromosome

Job Dekker, PhD, and scientists at Institut Curie in Paris and Stanford University have taken a detailed look inside the small, densely packed structure of the inactive X chromosome found in female mammals called the Barr body.

Students in High School Health Careers Program driven by dedication, determination

Students in High School Health Careers Program driven by dedication, determination

Eighteen local teenagers who are determined to do what it takes to succeed in careers in health care are members of UMass Medical School’s High School Health Careers Program Class of 2016.

Third Rock Ventures launches Fulcrum Therapeutics; Michael Green of UMMS a co-founder

Third Rock Ventures launches Fulcrum Therapeutics; Michael Green of UMMS a co-founder

Michael Green, MD, PhD, is one of five scientific co-founders of Fulcrum Therapeutics, a new company located in Cambridge’s Kendall Square focused on discovering and developing small molecules that modulate the on/off control mechanisms that regulate genes.

UMMS researchers discover novel link between immune system, social behavior

UMMS researchers discover novel link between immune system, social behavior

Vladimir Litvak, PhD, and colleagues made a startling discovery that immune system signaling can directly affect social behavior. Published in Nature, these findings could have great implications for neurological diseases such as autism-spectrum disorders and schizophrenia.

Long noncoding RNA found to quell inflammation

Long noncoding RNA found to quell inflammation

A long noncoding RNA (lincRNA)—called lincRNA-EPS—responsible for regulating innate immunity has been identified by a team of scientists at UMass Medical School. The findings were published in Cell. Katherine A. Fitzgerald, PhD, professor of medicine, is senior author on the study.

Peter Chai on CNBC explains how Google Glass can aid emergency patients

Peter Chai on CNBC explains how Google Glass can aid emergency patients

Peter R. Chai, MD, assistant professor of emergency medicine, discussed his research using Google Glass in the emergency department in a CNBC “The Spark” interview.

AP Big Story: UMass Medical School trains students to fight opioid abuse

AP Big Story: UMass Medical School trains students to fight opioid abuse

UMass Medical School is leading the charge to better train medical and advanced practice nursing students in the prevention and management of opioid abuse, according to an Associated Press story published June 28.

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