November 19, 2012
Ulrich H. von Andrian, MD, PhD, the Edward Mallinckrodt Jr. Professor of Immunopathology at Harvard Medical School, will deliver the 14th annual Fredric S. Fay Memorial Lecture “Not Always as Expected: Innate and Adaptive Immune Responses to Viral Infections.”
The Fred Fay lecture is given in remembrance of the late UMass Medical School professor of physiology and his scientific contributions, particularly to the field of biomedical imaging. It will be held on Thursday, Nov. 29, at 3 p.m. in the Arthur and Martha Pappas Amphitheatre (Amphitheatre I, S2-101).
Dr. von Andrian is a member of the European Academy of Science and has received numerous honors, including the David Pall Visiting Lectureship at the Cold Spring Harbor Laboratory, the American Society for Investigative Pathology’s Outstanding Investigator Award, the American Society of Physiology’s Henry Pickering Bowditch Award, the American Association of Immunologists’ BD Biosciences Investigator Award and the Microcirculatory Society’s Eugene Landis Award.
von Andrian is a pioneer in the development of multi-photon intravital microscopic techniques to visualize cellular interactions in the intact animal. The ability to observe cells in their native environment has produced a series of seminal discoveries. His early research defined the cellular interactions that underlie the trafficking of immune cells through the body. This work elucidated the multistep adhesion and signaling cascade that is required for immune cells to migrate from the microvasculature into the underlying tissue. This migratory process is required both for constitutive immune surveillance and rapidly-inducible inflammatory reactions. More recently, von Andrian has used intravital microscopy in conjunction with genetically engineered animals to characterize the cellular interactions that underlie the adaptive immune response, natural killer (NK) cell memory, viral pathogenesis and the circulatory patterns of stem cells.
For additional information, contact lecture host Ann R. Rittenhouse, PhD, associate professor of microbiology & physiological systems, at 508-856-3735.