Student Publications
UMass Medical School - Program in Neuroscience
2008
Ataman B, Ashley J, Gorczyca M, Ramachandran P, Fouquet W, Sigrist SJ, Budnik V (2008). Rapid activity-dependent modifications in synaptic structure and function require bidirectional Wnt signaling. Neuron 57: 705-718.
Connor CM, Akbarian S (2008). DNA methylation changes in schizophrenia and bipolar disorder. Epigenetics [Epub ahead of print]
Krashes MJ, Waddell S (2008). Drosophila memory: will orb(2) predict the future? Curr Biol. 18(2):R74-6.
Krashes MJ, Waddell S (2008). Rapid consolidation to a radish and protein synthesis-dependent long-term memory after single-session appetitive olfactory conditioning in Drosophila. J. Neurosci. 28: 3103-3113
Liu L, Heneghan JF, Michael GJ, Stanish LF, Egertova M, Rittenhouse AR (2008). L- and N-current but not M-current inhibition by M(1) muscarinic receptors requires DAG lipase activity. J Cell Physiol. 216: 91-100
Jiang Y, Matevossian A, Huang HS, Straubhaar J, Akbarian S (2008). Isolation of neuronal chromatin from brain tissue. BMC Neurosci. 2008 9:42
Schroeder FA, Penta KL, Matevossian A, Jones SR, Konradi C, Tapper AR, Akbarian S (2008). Drug-Induced Activation of Dopamine D(1) Receptor Signaling and Inhibition of Class I/II Histone Deacetylase Induce Chromatin Remodeling in Reward Circuitry and Modulate Cocaine-Related Behaviors. Neuropsychopharmacology. [Epub ahead of print; Feb 20, 2008]
Zhu H, Sauman I, Yuan Q, Casselman A, Emery-Le M, Emery P, Reppert SM (2008). Cryptochromes define a novel circadian clock mechanism in monarch butterflies that may underlie sun compass navigation. PLoS Biol. 6(1):e4.
Ziegenfuss JS, Biswas R, Avery MA, Hong K, Sheehan AE, Yeung Y-G, Stanley ER, Freeman MR (2008). Draper-dependent glial phagocytic activity is mediated by Src and Syk family kinase signalling. Nature. 2008 453:935-939
2007
Busza A, Murad A, Emery P (2007). Interactions between circadian neurons control temperature synchronization of Drosophila behavior. J. Neurosci 27: 10722-10733.
Difiglia M, Sena-Esteves M, Chase K, Sapp E, Pfister E, Sass M, Yoder J, Reeves P, Pandey RK, Rajeev KG, Manoharan M, Sah DW, Zamore PD, Aronin N (2007). Therapeutic silencing of mutant huntingtin with siRNA attenuates striatal and cortical neuropathology and behavioral deficits. Proc Natl Acad Sci U S A 104: 17204-17209.
Feinberg-Zadek PL, Treistman SN (2007). Beta-subunits are important modulators of the acute response to alcohol in human BK channels. Alcohol Clin Exp Res 31: 737-44.
Gorczyca D, Ashley J, Speese S, Gherbesi N, Thomas U, Gundelfinger E, Gramates LS, Budnik V (2007). Postsynaptic membrane addition depends on the Discs-Large-interacting t-SNARE Gtaxin. J Neurosci 27: 1033-1044.
Huang HS, Akbarian S (2007). GAD1 mRNA expression and DNA methylation in prefrontal cortex of subjects with schizophrenia. PLoS ONE 2:e809.
Huang HS, Matevossian A, Whittle C, Kim SY, Schumacher A, Baker SP, Akbarian S (2007). Prefrontal dysfunction in schizophrenia involves mixed-lineage leukemia 1-regulated histone methylation at GABAergic gene promoters. J Neurosci. 27: 11254-11262.
Kaushik R, Nawathean P, Busza A, Murad A, Emery P, Rosbash M (2007). PER-TIM interactions with the photoreceptor Cryptochrome mediate circadian temperature responses in Drosophila. PLoS Biol 5:e146.
Keene AC, Waddell S (2007). Drosophila odor memory: from single genes to complex neural circuits. Nat Rev Neurosci 8: 341-354.
Krashes MJ, Keene AC, Leung B, Armstrong JD, Waddell S (2007). Sequential use of mushroom body neuron subsets during Drosophila odor memory processing. Neuron 53: 103-115.
Li J, Ashley J, Budnik V, Bhat MA (2007) Crucial role of Drosophila neurexin in proper active zone apposition to postsynaptic densities, synaptic growth, and synaptic transmission. Neuron 55: 741-755.
Liu L, Heneghan JF, Mitra-Ganguli T, Roberts-Crowley M, Rittenhouse AR (2007). Role of PIP2 in regulating versus modulating Ca2+ channel activity. J Physiol 583: 1165-1167.
Murad A, Emery-Le M, Emery P (2007). A subset of Dorsal Neurons modulates circadian behavior and light responses in Drosophila. Neuron 53: 689-701.
Rickmyre JL, Dasgupta S, Ooi DL, Keel J, Lee E, Kirschner MW, Waddell S, Lee LA (2007). The Drosophila homolog of MCPH1, a human microcephaly gene, is required for genomic stability in the early embryo. J Cell Sci. 120: 03565-3677.
Schroeder FA, Lin CL, Crusio WE, Akbarian S (2007) Antidepressant-like effects of the histone deacetylase inhibitor, sodium butyrate, in the mouse. Biol Psychiatry 62: 55-64. (Epub Aug 30, 2006).
Siegmund KD, Connor CM, Campan M, Long TI, Weisenberger DJ, Biniszkiewicz D, Jaenisch R, Laird PW, Akbarian S (2007). DNA methylation in the human cerebral cortex is dynamically regulated throughout the life span and involves differentiated neurons. PLoS ONE 2:e895.
Shi L, Lin S, Grinberg Y, Beck Y, Grozinger CM, Robinson GE, Lee T (2007). Roles of Drosophila Kruppel-homolog 1 in neuronal morphogenesis. Dev Neurobiol 67: 1614-1626.
Shi L, Yu HH, Yang JS, Lee T (2007). Specific Drosophila Dscam juxtamembrane variants control dendritic elaboration and axonal arborization. J Neurosci 27: 6723-6728.
Soba P, Zhu S, Emoto K, Younger S, Yang SJ, Yu HH, Lee T, Jan LY, Jan YN (2007). Drosophila sensory neurons require Dscam for dendritic self-avoidance and proper dendritic field organization. Neuron 54: 403-416.
Yuan Q, Metterville D, Briscoe AD, Reppert SM (2007). Insect cryptochromes: Gene duplication and loss define diverse ways to construct insect circadian clocks. Mol Biol Evol 2007 Jan 22; 24: 948-955.
2006
Akbarian S, Huang HS (2006). Molecular and cellular mechanisms of altered GAD1/GAD67 expression in schizophrenia and related disorders. Brain Res Reviews 52: 293-304.
Akbarian S, Jiang Y, Laforet G (2006). The molecular pathology of Rett syndrome: synopsis and update. Neuromolecular Med 8: 485-494.
Ataman B, Ashley J, Gorczyca D, Gorczyca M, Mathew D, Wichmann C, Sigrist SJ, Budnik V (2006). Nuclear trafficking of Drosophila Frizzled-2 during synapse development requires the PDZ protein dGRIP. Proc Natl Acad Sci U S A 103: 7841-7846.
Ataman B, Budnik V, Thomas U (2006). Scaffolding porteins at the Drosophila neuromuscular junction. Int Rev Neurobiol 75: 181-216.
Beach M, MacDonald J, Porpiglia E, Sheehan AE, Watts RE, Freeman MR (2006). The Drosophila cell corpse engulfment receptor Draper mediates glial clearance of severed axons. Neuron 50: 869-881.
Ferris CF, Febo M, Luo F, Schmidt KF, Brevard M, Harder JA, Kulkarni P, Messenger T, King JA (2006). Functional magnetic resonance imaging in concious animals: A new tool in behavioral neuroscience research. J Neuroendocrinol 18: 307-318.
Freeman MR, Doherty J (2006). Glial cell biology in Drosophila and vertebrates. Trends Neurosci 29: 82-90.
Han J, Gong P, Reddig K, Mitra M, Guo P, Li HS (2006). The fly CAMTA transcription factor potentiates deactivation of rhodopsin, a G protein-coupled light receptor. Cell 127: 847-58.
Huang HS, Matevossian A, Jiang Y, Akbarian S (2006). Chromatin immunoprecipitation in postmortem brain. J Neurosci Methods 156: 284-292.
Keene AC, Krashes MJ, Leung BL, Bernard J, Waddell S (2006). Drosophila Dorsal Paired Medial neurons provide a general mechanism for memory consolidation. Current Biology 16: 1524-1530.
Rush BL, Murad A, Emery P, and Giebultowicz JM (2006). Ectopic CRYPTOCHROME renders TIM light sensitive in the Drosophila ovary. J Biol Rhythms 21: 272-278.
Henninger N, Sicard KM, Schmidt KF, Bardutzky J, Fisher M (2006). Comparison of ischemic lesion evolution in embolic vs. mechanical middle cerebral artery occlusion in Sprague Dawley rats using diffusion and perfusion imaging. Stroke 37: 1283-1287.
Lai SL, Lee T (2006). Genetic mosaic with dual binary transcriptional systems in Drosophila. Nat Neurosci 9: 703-709.
Schmidt KF, Febo M, Shen Q, Luo F, Sicard KM, Ferris CF, Stein EA, Duong TQ (2006). Hemodynamic and metabolic changes induced by cocaine in anesthetized rat observed with multimodal functional MRI. Psychopharmacology 185: 479-486.
Wynne P (2006). p38 mitogen-activated protein kinase: a novel modulator of hyperpolarization-activated cyclic nucleotide-gated channels and neuronal excitability. J Neurosci 26: 11253-11254.
2005
* Ashley J, *Packard M, Ataman B, and Budnik V (2005). Fasciclin II signals new synapse formation through amyloid precursor protein and the scaffolding protein dX11/Mint. J Neurosci 25: 5943-5955.Mathew D, Ataman B, Chen J, Zhang Y, Cumberledge S, Budnik V (2005) Wingless signaling at synapses is through cleavage and nuclear import of receptor DFrizzled2. Science 310: 1344-1347.
Crowley JJ, Treistman SN, Dopico AM (2005). Distinct structural features of phospholipids differentially determine ethanol sensitivity and basal function of BK channels. Mol Pharmacol 68: 4-10.
Febo M, Segarra AC, Nair G, Schmidt K, Duong TQ, Ferris CF (2005). The neural consequences of repeated cocaine exposure revealed by functional MRI in awake rats. Neuropsychopharmacol 30: 936-943.
Keene AC, Waddell S (2005). Drosophila memory: dopamine signals punishment? Curr Biol 15:R932-934.
Knott TK, Velazquez-Marrero C, Lemos JR (2005). ATP elicits inward currents in isolated vasopressinergic neurohypophysial terminals via P2X2 and P2X3 receptors. Pflugers Arch 450: 381-389.
Lambert CM, Machida KK, Smale L, Nunez AA, Weaver DR (2005). Analysis of the prokineticin 2 system in a diurnal rodent, the unstriped Nile grass rat (Arvicanthis niloticus). J Biol Rhythms 20: 206-218.
Newton PM, Tully K, McMahon T, Connolly J, Dadgar J, Treistman SN, Messing RO (2005). Chronic ethanol exposure induces an N-type calcium channel splice variant with altered channel kinetics. FEBS Lett 579: 671-676.
Sauman I, Briscoe AD, Zhu H, Shi D, Froy O, Stalleicken J, Yuan Q, Casselman A, and Reppert SM (2005). Connecting the navigational clock to sun compass input in Monarch butterfly brain. Neuron 46: 457-467.
Yu D, Keene AC, Srivatsan A, Waddell S, Davis RL (2005). Drosophila DPM neurons form a delayed and branch-specific memory trace after olfactory classical conditioning. Cell 123: 945-957.
Zhu H, Yuan Q, Froy O, Casselman A, Reppert SM (2005). The two CRYs of the butterfly. Curr Biol 15:R953-4.
2004
Busza A, Emery-Le M, Rosbash M, Emery P (2004). Roles of the two Drosophila CRYPTOCHROME structural domains in circadian photoreception. Science 304: 1503-1506.
De Crescenzo V, ZhuGe R, Velazquez-Marrero C, Lifshitz LM, Custer E, Carmichael J, Lai FA, Tuft RA, Fogarty KE, Lemos JR, Walsh JV Jr (2004). Ca2+ syntillas, miniature Ca2+ release events in terminals of hypothalamic neurons, are increased in frequency by depolarization in the absence of Ca2+ influx. J Neurosci 24: 1226-1235.
Keene AC, Stratmann M, Keller A, Perrat PN, Vosshall LB, Waddell S (2004). Diverse odor-conditioned memories require uniquely times dorsal paired medial neuron output. Neuron 44: 521-533.
McNally JM, Woodbury DJ, Lemos JR (2004). Syntaxin 1A drives fusion of large dense-core neurosecretory granules into a planar lipid bilayer. Cell Biochem Biophys 41: 11-24.
Li J, Guo Y, Schroeder FA, Youngs RM, Schmidt TW, Ferris C, Konradi C, Akbarian S (2004). Dopamine D2-like antagonists induce chromatin remodeling in striatal neurons through cyclic AMP-protein kinase A and NMDA receptor signaling. J Neurochem 90: 1117-1131.
Liu L, Roberts ML, Rittenhouse AR (2004). Phospholipid metabolism is required for M(1) muscarinic inhibition of N-type calcium current in sympathetic neurons. Eur Biophys J 33: 255-264.
Liu ZM, Schmidt KF, Sicard KM (2004). Imaging oxygen consumption in forepaw somatosensory stimulation in rats under isoflurane anesthesia. Magnetic Res Med 52: 277-285.
Martin G, Puig S, Pietrzykowski A, Zadek P, Emery P, Treistman S (2004). Somatic localization of a specific BK-channel subtype controls compartmentalized ethanol sensitivity in the nucleus accumbens. J Neurosci 24: 6563-6572.
Ruiz-Canada C, Ashley J, Moeckel-Cole S, Drier E, Yin J, Budnik V (2004). New synaptic bouton formation is disrupted by misregulation of microtubule stability in aPKC mutants. Neuron 42: 567-580.
Tully K, Treistman SN (2004). Distinct intracellular calcium profiles following influx through N- versus L-type calcium channels: role of Ca2+-induced Ca2+ release. J Neurophysiol 92:135-43.
Yuan C, O'Connell RJ,
Feinberg-Zadek PL, Johnston LJ, Treistman SN (2004). Bilayer thickness modulates the conductance of the BK channel in model membranes.
Biophys J 86: 3620-3633.
2003
Crowley JJ, Treistman SN, Dopico AM (2003). Cholesterol antagonizes ethanol potentiation of human brain BKCa channels reconstituted into phospholipid bilayers.
Mol Pharmacol 64: 365-372.
Ding H, Schwarz DS, Keene A, Affar el B, Fenton L, Xia X, Shi Y, Zamore PD, Xu Z (2003). Selective silencing by RNAi of a dominant allele that causes amyotrophic lateral sclerosis. Aging Cell 2: 209-217.
Only publications resulting from graduate work at UMass Med School are included; for additional publications, search PubMed.