Graduate Student Publications

Department of Neurobiology 

Graduate student names are in bold font.

Other student names are indicated by an asterisk. 

Students are only identified in the section for their advisor.

Student Publications of Current Faculty

Mark J. Alkema                       Neurobiology Department member 2005- 

Claire Y. Bénard                      Neurobiology Department member 2009- 

Vivian Budnik                          Neurobiology Department member 2003- 

Patrick Emery                         Neurobiology Department member 2001- 

Michael M. Francis                  Neurobiology Department member 2007- 

Marc R. Freeman                    Neurobiology Department member 2004- 

Hong-Sheng Li                        Neurobiology Department member 2002- 

Steven M. Reppert                  Neurobiology Department member 2001- 

Dorothy P. Schafer                  Neurobiology Department member 2015- 

David R. Weaver                     Neurobiology Department member 2001- 

Yang Xiang                              Neurobiology Department member 2012- 

 

Student Publications of Faculty Alumni

Tzumin Lee                             Neurobiology Department member 2005- 2009

Carlos Lois                              Neurobiology Department member 2010- 2015

Steven N. Treistman                Neurobiology Department member 2001- 2005

Scott Waddell                         Neurobiology Department member 2001- 2011

Motojiro Yoshihara                  Neurobiology Department member 2006- 2013

 

Student Publications from the Alkema Lab (established at UMMS in 2005) 

Graduates:

      Jamie L. Donnelly, Ph.D.              2011       Neuroscience Program

      Jennifer K. Pirri, Ph.D.                 2013       Neuroscience Program

      Christopher M. Clark, Ph.D.          2014       Neuroscience Program

Current students:

      Jeremy Florman                                         Neuroscience Program

      Yung-Chi Huang                                          Interdisciplinary Graduate Program

 

Sun L, Shay J, McLoed M, Roodhouse K, Chung SH, Clark CM, Pirri JK, Alkema MJ, Gabel CV. Neuronal regeneration in C. elegans requires subcellular calcium release by ryanodine receptor channels and can be enhanced by optogenetic stimulation. J Neurosci. 2014 Nov 26; 34(48):15947-56. 
View in: PubMed

Bhattacharya R, Touroutine D, Barbagallo B, Climer J, Lambert CM, Clark CM, Alkema MJ, Francis MM. A conserved dopamine-cholecystokinin signaling pathway shapes context-dependent Caenorhabditis elegans behavior. PLoS Genet. 2014 Aug; 10(8):e1004584. 
View in: PubMed

Shipley FB, Clark CM, Alkema MJ, Leifer AM. Simultaneous optogenetic manipulation and calcium imaging in freely moving C. elegans. Front Neural Circuits. 2014; 8:28. 
View in: PubMed

Donnelly JL, Clark CM, Leifer AM, Pirri JK, Haburcak M, Francis MM, Samuel AD, Alkema MJ. Monoaminergic orchestration of motor programs in a complex C. elegans behavior. PLoS Biol. 2013; 11(4):e1001529. 
View in: PubMed

Schumacher JA, Hsieh YW, Chen S, Pirri JK, Alkema MJ, Li WH, Chang C, Chuang CF. Intercellular calcium signaling in a gap junction-coupled cell network establishes asymmetric neuronal fates in C. elegans. Development. 2012 Nov; 139(22):4191-201. 
View in: PubMed

Pirri JK, Alkema MJ. The neuroethology of C. elegans escape. Curr Opin Neurobiol. 2012 Apr; 22(2):187-93. 
View in: PubMed

Maguire SM, Clark CM, Nunnari J, Pirri JK, Alkema MJ. The C. elegans touch response facilitates escape from predacious fungi. Curr Biol. 2011 Aug 9; 21(15):1326-30. 
View in: PubMed

Pirri JK, McPherson AD, Donnelly JL, Francis MM, Alkema MJ. A tyramine-gated chloride channel coordinates distinct motor programs of a Caenorhabditis elegans escape response. Neuron. 2009 May 28; 62(4):526-38. 
View in: PubMed

 

Student Publications from the Bénard lab  (established at UMMS in 2009) 

Current students:

      Cassie Blanchette                                       Neuroscience Program

      Anagha (Kulkarni) Khandekar                      Neuroscience Program

      Devyn Oliver                                              Neuroscience Program  (with Mike Francis)

 

Blanchette C, Perrat PN, Thackeray A, Bénard CY.  Glypican is a modulator of netrin-mediated axon guidance. PLoS Biol. 2015; 13(7):e1002183. doi: 10.1371/journal.pbio.1002183. PMID: 26148345  View in: PubMed 

Bénard CY, Blanchette C, Recio J, Hobert O. The secreted immunoglobulin domain proteins ZIG-5 and ZIG-8 cooperate with L1CAM/SAX-7 to maintain nervous system integrity. PLoS Genet. 2012; 8(7):e1002819.  View in: PubMed

 

Student Publications from the Budnik Lab

Student Publications from the Budnik Lab at UMMS (2003- )

Graduates:

      James Ashley, Ph.D.                     2006       Neuroscience Program 

      Bulent Ataman, Ph.D.                   2008       Neuroscience Program

      Preethi Ramachandran, Ph.D.       2009       Neuroscience Program  

      Alex C. Koon, Ph.D.                      2011       Neuroscience Program

      Ceren Korkut, Ph.D.                     2012       Neuroscience Program

      Yuly Fuentez-Medel, Ph.D.           2012       Neuroscience Program   (with Marc Freeman)

Current students:

     Yi-Hang Li                                                   Neuroscience Program

     Vahbiz Jokhi                                               Neuroscience Program

Other students:

      David Gorczyca* was a UMass Amherst undergraduate and summer intern.

 

Kerr KS, Fuentes-Medel Y, Brewer C, Barria R, Ashley J, Abruzzi KC, Sheehan A, Tasdemir-Yilmaz OE, Freeman MR, Budnik V. Glial wingless/wnt regulates glutamate receptor clustering and synaptic physiology at the Drosophila neuromuscular junction. J Neurosci. 2014 Feb 19; 34(8):2910-20. 
View in: PubMed

Jokhi V, Ashley J, Nunnari J, Noma A, Ito N, Wakabayashi-Ito N, Moore MJ, Budnik V. Torsin mediates primary envelopment of large ribonucleoprotein granules at the nuclear envelope. Cell Rep. 2013 Apr 25; 3(4):988-95. 
View in: PubMed

Korkut C, Li Y, Koles K, Brewer C, Ashley J, Yoshihara M, Budnik V. Regulation of postsynaptic retrograde signaling by presynaptic exosome release. Neuron. 2013 Mar 20; 77(6):1039-46. 
View in: PubMed

Fuentes-Medel Y, Ashley J, Barria R, Maloney R, Freeman M, Budnik V. Integration of a retrograde signal during synapse formation by glia-secreted TGF-ß ligand. Curr Biol. 2012 Oct 9; 22(19):1831-8. 
View in: PubMed

Speese SD, Ashley J, Jokhi V, Nunnari J, Barria R, Li Y, Ataman B, Koon A, Chang YT, Li Q, Moore MJ, Budnik V. Nuclear envelope budding enables large ribonucleoprotein particle export during synaptic Wnt signaling. Cell. 2012 May 11; 149(4):832-46. 
View in: PubMed

Koon AC, Budnik V. Inhibitory control of synaptic and behavioral plasticity by octopaminergic signaling. J Neurosci. 2012 May 2; 32(18):6312-22. 
View in: PubMed

Koles K, Nunnari J, Korkut C, Barria R, Brewer C, Li Y, Leszyk J, Zhang B, Budnik V. Mechanism of evenness interrupted (Evi)-exosome release at synaptic boutons. J Biol Chem. 2012 May 11; 287(20):16820-34. 
View in: PubMed

Koon AC, Ashley J, Barria R, DasGupta S, Brain R, Waddell S, Alkema MJ, Budnik V. Autoregulatory and paracrine control of synaptic and behavioral plasticity by octopaminergic signaling. Nat Neurosci. 2011 Feb; 14(2):190-9. 
View in: PubMed

Ramachandran P, Budnik V. Preparation of early Drosophila embryonic fillets (before cuticle deposition). Cold Spring Harb Protoc. 2010 Oct; 2010(10):pdb.prot5497. 
View in: PubMed

Ramachandran P, Budnik V. Preparation of late Drosophila embryonic fillets. Cold Spring Harb Protoc. 2010 Oct; 2010(10):pdb.prot5498. 
View in: PubMed

Ramachandran P, Budnik V. Activity paradigm to induce Drosophila larval neuromuscular junction growth. Cold Spring Harb Protoc. 2010 Aug; 2010(8):pdb.prot5473. 
View in: PubMed

Ramachandran P, Budnik V. Dissection of Drosophila larval body-wall muscles. Cold Spring Harb Protoc. 2010 Aug; 2010(8):pdb.prot5469. 
View in: PubMed

Ramachandran P, Budnik V. Fm1-43 labeling of Drosophila larval neuromuscular junctions. Cold Spring Harb Protoc. 2010 Aug; 2010(8):pdb.prot5471. 
View in: PubMed

Ramachandran P, Budnik V. Internalization and trafficking assay for Drosophila larvae. Cold Spring Harb Protoc. 2010 Aug; 2010(8):pdb.prot5472. 
View in: PubMed

Ramachandran P, Budnik V. Electron microscopy of Drosophila larval neuromuscular junctions. Cold Spring Harb Protoc. 2010 Aug; 2010(8):pdb.prot5474. 
View in: PubMed

Ramachandran P, Budnik V. Immunocytochemical staining of Drosophila larval body-wall muscles. Cold Spring Harb Protoc. 2010 Aug; 2010(8):pdb.prot5470. 
View in: PubMed

Fuentes-Medel Y, Budnik V. Ménage à Trio during BMP-Mediated Retrograde Signaling at the NMJ. Neuron. 2010 May 27; 66(4):473-5. 
View in: PubMed

Korkut C, Ataman B, Ramachandran P, Ashley J, Barria R, Gherbesi N, Budnik V. Trans-synaptic transmission of vesicular Wnt signals through Evi/Wntless. Cell. 2009 Oct 16; 139(2):393-404. 
View in: PubMed

Korkut C, Budnik V. WNTs tune up the neuromuscular junction. Nat Rev Neurosci. 2009 Sep; 10(9):627-34. 
View in: PubMed

Fuentes-Medel Y, Logan MA, Ashley J, Ataman B, Budnik V, Freeman MR. Glia and muscle sculpt neuromuscular arbors by engulfing destabilized synaptic boutons and shed presynaptic debris. PLoS Biol. 2009 Aug; 7(8):e1000184. 
View in: PubMed

Ramachandran P, Barria R, Ashley J, Budnik V. A critical step for postsynaptic F-actin organization: regulation of Baz/Par-3 localization by aPKC and PTEN. Dev Neurobiol. 2009 Aug; 69(9):583-602. 
View in: PubMed

Ataman B, Ashley J, Gorczyca M, Ramachandran P, Fouquet W, Sigrist SJ, Budnik V. Rapid activity-dependent modifications in synaptic structure and function require bidirectional Wnt signaling. Neuron. 2008 Mar 13; 57(5):705-18. 
View in: PubMed

Li J, Ashley J, Budnik V, Bhat MA. Crucial role of Drosophila neurexin in proper active zone apposition to postsynaptic densities, synaptic growth, and synaptic transmission. Neuron. 2007 Sep 6; 55(5):741-55. 
View in: PubMed

Gorczyca D*, Ashley J, Speese S, Gherbesi N, Thomas U, Gundelfinger E, Gramates LS, Budnik V. Postsynaptic membrane addition depends on the Discs-Large-interacting t-SNARE Gtaxin. J Neurosci. 2007 Jan 31; 27(5):1033-44. 
View in: PubMed

Ataman B, Ashley J, Gorczyca D, Gorczyca M, Mathew D, Wichmann C, Sigrist SJ, Budnik V. Nuclear trafficking of Drosophila Frizzled-2 during synapse development requires the PDZ protein dGRIP. Proc Natl Acad Sci U S A. 2006 May 16; 103(20):7841-6. 
View in: PubMed

Ataman B, Budnik V, Thomas U. Scaffolding proteins at the Drosophila neuromuscular junction. Int Rev Neurobiol. 2006; 75:181-216. 
View in: PubMed

Mathew D, Ataman B, Chen J, Zhang Y, Cumberledge S, Budnik V. Wingless signaling at synapses is through cleavage and nuclear import of receptor DFrizzled2. Science. 2005 Nov 25; 310(5752):1344-7. 
View in: PubMed

Ashley J, Packard M, Ataman B, Budnik V. Fasciclin II signals new synapse formation through amyloid precursor protein and the scaffolding protein dX11/Mint. J Neurosci. 2005 Jun 22; 25(25):5943-55. 
View in: PubMed

Ruiz-Canada C, Ashley J, Moeckel-Cole S, Drier E, Yin J, Budnik V. New synaptic bouton formation is disrupted by misregulation of microtubule stability in aPKC mutants. Neuron. 2004 May 27; 42(4):567-80. 
View in: PubMed

 

Student Publications from the Budnik Lab at UMass-Amherst (1990-2003)

Graduates:

      YH Koh completed doctoral studies at UMass-Amherst

      LS Gramates completed doctoral studies at UMass-Amherst

      Mary Packard completed doctoral studies at UMass-Amherst

      Dennis Mathew began graduate studies and received his PhD from UMass-Amherst, but his research was completed at UMMS)

      James Ashley began graduate studies at UMass-Amherst and received his PhD from UMMS

      Bulent Ataman began graduate studies at UMass-Amherst and received his PhD from UMMS

 

Ataman B, Ashley J, Gorczyca D, Gorczyca M, Mathew D, Wichmann C, Sigrist SJ, Budnik V. Nuclear trafficking of Drosophila Frizzled-2 during synapse development requires the PDZ protein dGRIP. Proc Natl Acad Sci U S A. 2006 May 16; 103(20):7841-6. 
View in: PubMed

Mathew D, Ataman B, Chen J, Zhang Y, Cumberledge S, Budnik V. Wingless signaling at synapses is through cleavage and nuclear import of receptor DFrizzled2. Science. 2005 Nov 25; 310(5752):1344-7. 
View in: PubMed

Mathew D, Popescu A, Budnik V. Drosophila amphiphysin functions during synaptic Fasciclin II membrane cycling. J Neurosci. 2003 Nov 19; 23(33):10710-6. 
View in: PubMed

Packard M, Mathew D, Budnik V. FASt remodeling of synapses in Drosophila. Curr Opin Neurobiol. 2003 Oct; 13(5):527-34. 
View in: PubMed

Packard M, Mathew D, Budnik V. Wnts and TGF beta in synaptogenesis: old friends signalling at new places. Nat Rev Neurosci. 2003 Feb; 4(2):113-20. 
View in: PubMed

Mathew D, Gramates LS, Packard M, Thomas U, Bilder D, Perrimon N, Gorczyca M, Budnik V. Recruitment of scribble to the synaptic scaffolding complex requires GUK-holder, a novel DLG binding protein. Curr Biol. 2002 Apr 2; 12(7):531-9. 
View in: PubMed

Koh YH, Ruiz-Canada C, Gorczyca M, Budnik V. The Ras1-mitogen-activated protein kinase signal transduction pathway regulates synaptic plasticity through fasciclin II-mediated cell adhesion. J Neurosci. 2002 Apr 1; 22(7):2496-504. 
View in: PubMed

Thomas U, Ebitsch S, Gorczyca M, Koh YH, Hough CD, Woods D, Gundelfinger ED, Budnik V. Synaptic targeting and localization of discs-large is a stepwise process controlled by different domains of the protein. Curr Biol. 2000 Sep 21; 10(18):1108-17. 
View in: PubMed

Koh YH, Gramates LS, Budnik V. Drosophila larval neuromuscular junction: molecular components and mechanisms underlying synaptic plasticity. Microsc Res Tech. 2000 Apr 1; 49(1):14-25. 
View in: PubMed

Koh YH, Popova E, Thomas U, Griffith LC, Budnik V. Regulation of DLG localization at synapses by CaMKII-dependent phosphorylation. Cell. 1999 Aug 6; 98(3):353-63. 
View in: PubMed

Gramates LS, Budnik V. Assembly and maturation of the Drosophila larval neuromuscular junction. Int Rev Neurobiol. 1999; 43:93-117. 
View in: PubMed

Budnik V, Koh YH, Guan B, Hartmann B, Hough C, Woods D, Gorczyca M. Regulation of synapse structure and function by the Drosophila tumor suppressor gene dlg. Neuron. 1996 Oct; 17(4):627-40. 
View in: PubMed

Guan B, Hartmann B, Koh YH, Gorczyca M, Budnik V. The Drosophila tumor suppressor gene, dlg, is involved in structural plasticity at a glutamatergic synapse. Curr Biol. 1996 Jun 1; 6(6):695-706. 
View in: PubMed

 

Student Publications from the Emery Lab at UMMS (established in 2001)

Graduates:

      Ania Busza, M.D., Ph.D.               2009       MD/PhD program

      Jinli Ling, Ph.D.                           2013       Neuroscience Program

      Alejandro Murad, Ph.D.                2007       Neuroscience Program 

Current students:

      Lauren Foley                                              Neuroscience Program

      Pallavi Lamba                                            Neuroscience Program

      Elaine Chang                                              Neuroscience Program

      Monika Chitre                                             Interdisciplinary Graduate Program

 

Lamba P, Bilodeau-Wentworth D, Emery P, Zhang Y. Morning and evening oscillators cooperate to reset circadian behavior in response to light input. Cell Rep. 2014 May 8; 7(3):601-8. 
View in: PubMed

Zhang Y, Ling J, Yuan C, Dubruille R, Emery P. A role for Drosophila ATX2 in activation of PER translation and circadian behavior. Science. 2013 May 17; 340(6134):879-82. 
View in: PubMed

Ling J, Dubruille R, Emery P. KAYAK-a modulates circadian transcriptional feedback loops in Drosophila pacemaker neurons. J Neurosci. 2012 Nov 21; 32(47):16959-70. 
View in: PubMed

Kaneko H, Head LM, Ling J, Tang X, Liu Y, Hardin PE, Emery P, Hamada FN. Circadian rhythm of temperature preference and its neural control in Drosophila. Curr Biol. 2012 Oct 9; 22(19):1851-7. 
View in: PubMed

Dubruille R, Murad A, Rosbash M, Emery P. A constant light-genetic screen identifies KISMET as a regulator of circadian photoresponses. PLoS Genet. 2009 Dec; 5(12):e1000787. 
View in: PubMed

Busza A, Murad A, Emery P. Interactions between circadian neurons control temperature synchronization of Drosophila behavior. J Neurosci. 2007 Oct 3; 27(40):10722-33. 
View in: PubMed

Kaushik R, Nawathean P, Busza A, Murad A, Emery P, Rosbash M. PER-TIM interactions with the photoreceptor cryptochrome mediate circadian temperature responses in Drosophila. PLoS Biol. 2007 Jun; 5(6):e146. 
View in: PubMed

Murad A, Emery-Le M, Emery P. A subset of dorsal neurons modulates circadian behavior and light responses in Drosophila. Neuron. 2007 Mar 1; 53(5):689-701. 
View in: PubMed

Rush BL, Murad A, Emery P, Giebultowicz JM. Ectopic CRYPTOCHROME renders TIM light sensitive in the Drosophila ovary. J Biol Rhythms. 2006 Aug; 21(4):272-8. 
View in: PubMed

Busza A, Emery-Le M, Rosbash M, Emery P. Roles of the two Drosophila CRYPTOCHROME structural domains in circadian photoreception. Science. 2004 Jun 4; 304(5676):1503-6. 
View in: PubMed

 

Student Publications from the Francis Lab (established at UMMS in 2007)

Graduates:

     Hilary (Prescott) Petrash, Ph.D.      2012      Neuroscience Program

     Belinda Barbagallo, Ph.D.               2014      Neuroscience Program

Current students:

      Navonil Banerjee                                       Neuroscience Program

      Allison Philbrook                                        Neuroscience Program

      Devyn Oliver                                              Neuroscience Program (with Claire Bénard)

Other Students: 

      Jason Climber* was an undergraduate at WPI at the time of his participation at UMMS.

 

Bhattacharya R, Touroutine D, Barbagallo B, Climer J* Lambert CM, Clark CM, Alkema MJ, Francis MM. A Conserved Dopamine-Cholecystokinin Signaling Pathway Shapes Context-Dependent Caenorhabditis elegans Behavior. PLoS Genet. 2014 Aug; 10(8):e1004584. 
View in: PubMed

Philbrook A, Barbagallo B, Francis MM. A tale of two receptors: Dual roles for ionotropic acetylcholine receptors in regulating motor neuron excitation and inhibition. Worm. 2013 Jul 1; 2(3):e25765. 
View in: PubMed

Petrash HA, Philbrook A, Haburcak M, Barbagallo B, Francis MM. ACR-12 ionotropic acetylcholine receptor complexes regulate inhibitory motor neuron activity in Caenorhabditis elegans. J Neurosci. 2013 Mar 27; 33(13):5524-32. 
View in: PubMed

Barbagallo B, Prescott HA, Boyle P, Climer J*, Francis MM. A dominant mutation in a neuronal acetylcholine receptor subunit leads to motor neuron degeneration in Caenorhabditis elegans. J Neurosci. 2010 Oct 20; 30(42):13932-42. 
View in: PubMed

 

Student Publications from the Freeman Lab (established at UMMS in 2004)

Graduates:

      Michelle A. Avery, Ph.D.               2010       Neuroscience Program

      Johnna Doherty, Ph.D.                  2012       Neuroscience Program

      Jennifer S. Zeigenfuss, Ph.D.        2012       Neuroscience Program

      Yuly Fuentes-Medel, Ph.D.            2012       Neuroscience Program (with Vivian Budnik)

      Kimberly S. Kerr, Ph.D.                 2012       Neuroscience Program

      Jeannette M. Osterloh, Ph.D.        2013       Neuroscience Program

      Ozge Tasdemir-Yilmaz, Ph.D.        2014       Neuroscience Program

      Jennifer MacDonald, MD, Ph.D.     2014       MD/PhD Program

      Allie K. Muthukumar, Ph.D.           2015       Neuroscience Program

      Timothy M. Rooney                       (2017)     MD/PhD Program

Current Students:

      Thomas C. Burdett                                       Neuroscience Program

      Sukhee Cho                                                  Neuroscience Program

      Jonathan Farley                                           Neuroscience Program

      Yonca Karadeniz                                          Neuroscience Program

      Elizabeth Lewis                                            Neuroscience Program

      Tsai Yi Lu                                                     Interdisciplinary Graduate Program

Other students:

    Margaret G. Beach*                         2007         M.S., Neuroscience Program

    Ermalinda Porpiglia*                                       (Completed PhD elsewhere in UMMS)

 

Doherty J, Sheehan AE, Bradshaw R, Fox AN, Lu TY, Freeman MR. PI3K Signaling and Stat92E Converge to Modulate Glial Responsiveness to Axonal Injury. PLoS Biol. 2014 Nov; 12(11):e1001985. 
View in: PubMed

Muthukumar AK, Stork T, Freeman MR. Activity-dependent regulation of astrocyte GAT levels during synaptogenesis. Nat Neurosci. 2014 Oct; 17(10):1340-50. 
View in: PubMed

Lu TY, Doherty J, Freeman MR. DRK/DOS/SOS converge with Crk/Mbc/dCed-12 to activate Rac1 during glial engulfment of axonal debris. Proc Natl Acad Sci U S A. 2014 Aug 26; 111(34):12544-9. 
View in: PubMed

Burdett TC, Freeman MR. Neuroscience. Astrocytes eyeball axonal mitochondria. Science. 2014 Jul 25; 345(6195):385-6. 
View in: PubMed

Stork T, Sheehan A, Tasdemir-Yilmaz OE, Freeman MR. Neuron-Glia Interactions through the Heartless FGF Receptor Signaling Pathway Mediate Morphogenesis of Drosophila Astrocytes. Neuron. 2014 Jul 16; 83(2):388-403. 
View in: PubMed

Neukomm LJ, Burdett TC, Gonzalez MA, Züchner S, Freeman MR. Rapid in vivo forward genetic approach for identifying axon death genes in Drosophila. Proc Natl Acad Sci U S A. 2014 Jul 8; 111(27):9965-70. 
View in: PubMed

Kerr KS, Fuentes-Medel Y, Brewer C, Barria R, Ashley J, Abruzzi KC, Sheehan A, Tasdemir-Yilmaz OE, Freeman MR, Budnik V. Glial wingless/wnt regulates glutamate receptor clustering and synaptic physiology at the Drosophila neuromuscular junction. J Neurosci. 2014 Feb 19; 34(8):2910-20. 
View in: PubMed

Rooney TM, Freeman MR. Drosophila models of neuronal injury. ILAR J. 2014 Jan; 54(3):291-5. 
View in: PubMed

Tasdemir-Yilmaz OE, Freeman MR. Astrocytes engage unique molecular programs to engulf pruned neuronal debris from distinct subsets of neurons. Genes Dev. 2014 Jan 1; 28(1):20-33. 
View in: PubMed

MacDonald JM, Doherty J, Hackett R, Freeman MR. The c-Jun kinase signaling cascade promotes glial engulfment activity through activation of draper and phagocytic function. Cell Death Differ. 2013 Sep; 20(9):1140-8. 
View in: PubMed

Fuentes-Medel Y, Ashley J, Barria R, Maloney R, Freeman M, Budnik V. Integration of a retrograde signal during synapse formation by glia-secreted TGF-ß ligand. Curr Biol. 2012 Oct 9; 22(19):1831-8. View in: PubMed

Wishart TM, Rooney TM, Lamont DJ, Wright AK, Morton AJ, Jackson M, Freeman MR, Gillingwater TH. Combining comparative proteomics and molecular genetics uncovers regulators of synaptic and axonal stability and degeneration in vivo. PLoS Genet. 2012; 8(8):e1002936. 
View in: PubMed

Ziegenfuss JS, Doherty J, Freeman MR. Distinct molecular pathways mediate glial activation and engulfment of axonal debris after axotomy. Nat Neurosci. 2012 Jul; 15(7):979-87. 
View in: PubMed

Osterloh JM, Yang J, Rooney TM, Fox AN, Adalbert R, Powell EH, Sheehan AE, Avery MA, Hackett R, Logan MA, MacDonald JM, Ziegenfuss JS, Milde S, Hou YJ, Nathan C, Ding A, Brown RH, Conforti L, Coleman M, Tessier-Lavigne M, Züchner S, Freeman MR. dSarm/Sarm1 is required for activation of an injury-induced axon death pathway. Science. 2012 Jul 27; 337(6093):481-4. 
View in: PubMed

Logan MA, Hackett R, Doherty J, Sheehan A, Speese SD, Freeman MR. Negative regulation of glial engulfment activity by Draper terminates glial responses to axon injury. Nat Neurosci. 2012 May; 15(5):722-30. 
View in: PubMed

Avery MA, Rooney TM, Pandya JD, Wishart TM, Gillingwater TH, Geddes JW, Sullivan PG, Freeman MR. WldS prevents axon degeneration through increased mitochondrial flux and enhanced mitochondrial Ca2+ buffering. Curr Biol. 2012 Apr 10; 22(7):596-600. 
View in: PubMed

Osterloh JM, Freeman MR. Neuronal death or dismemberment mediated by Sox14. Nat Neurosci. 2009 Dec; 12(12):1479-80. 
View in: PubMed

Fuentes-Medel Y, Logan MA, Ashley J, Ataman B, Budnik V, Freeman MR. Glia and muscle sculpt neuromuscular arbors by engulfing destabilized synaptic boutons and shed presynaptic debris. PLoS Biol. 2009 Aug; 7(8):e1000184. 
View in: PubMed

Doherty J, Logan MA, Tasdemir OE, Freeman MR. Ensheathing glia function as phagocytes in the adult Drosophila brain. J Neurosci. 2009 Apr 15; 29(15):4768-81. 
View in: PubMed

Avery MA, Sheehan AE, Kerr KS, Wang J, Freeman MR. Wld S requires Nmnat1 enzymatic activity and N16-VCP interactions to suppress Wallerian degeneration. J Cell Biol. 2009 Feb 23; 184(4):501-13. 
View in: PubMed

Ziegenfuss JS, Biswas R, Avery MA, Hong K, Sheehan AE, Yeung YG, Stanley ER, Freeman MR. Draper-dependent glial phagocytic activity is mediated by Src and Syk family kinase signalling. Nature. 2008 Jun 12; 453(7197):935-9. 
View in: PubMed

MacDonald JM, Beach MG*, Porpiglia E*, Sheehan AE, Watts RJ, Freeman MR. The Drosophila cell corpse engulfment receptor Draper mediates glial clearance of severed axons. Neuron. 2006 Jun 15; 50(6):869-81. 
View in: PubMed

Freeman MR, Doherty J. Glial cell biology in Drosophila and vertebrates. Trends Neurosci. 2006 Feb; 29(2):82-90. 
View in: PubMed

 

Student Publications from the Li Lab (established at UMMS in 2002)

Graduates:

      Peiyi Guo, Ph.D.                            2010       Neuroscience Program

      Lina Ni, Ph.D.                                2010       Neuroscience Program

Current Students:

      Caitlin Quigley                                              MD/PhD Program

 

Luan Z, Quigley C, Li HS. The putative Na(+)/Cl(-)-dependent neurotransmitter/osmolyte transporter inebriated in the Drosophila hindgut is essential for the maintenance of systemic water homeostasis. Sci Rep. 2015; 5:7993. 
View in: PubMed

Ni L, Guo P, Reddig K, Mitra M, Li HS. Mutation of a TADR protein leads to rhodopsin and Gq-dependent retinal degeneration in Drosophila. J Neurosci. 2008 Dec 10; 28(50):13478-87. 
View in: PubMed

Han J, Gong P, Reddig K, Mitra M, Guo P, Li HS. The fly CAMTA transcription factor potentiates deactivation of rhodopsin, a G protein-coupled light receptor. Cell. 2006 Nov 17; 127(4):847-58. 
View in: PubMed

 

Student Publications from the Reppert Lab

Student Publications from the Reppert Lab at UMMS (2001- )

Graduates:

      Quan Yuan, Ph.D.                            2009       Neuroscience Program

Other Students:

      DingDing Shi*, Ph.D.                                       Degree completed elsewhere within UMMS

      Dennis C. Chang, Ph.D.                                  Harvard Medical School PhD completed at UMMS

 

Zhu H, Sauman I, Yuan Q, Casselman A, Emery-Le M, Emery P, Reppert SM. Cryptochromes define a novel circadian clock mechanism in monarch butterflies that may underlie sun compass navigation. PLoS Biol. 2008 Jan; 6(1):e4. 
View in: PubMed

Yuan Q, Metterville D, Briscoe AD, Reppert SM. Insect cryptochromes: gene duplication and loss define diverse ways to construct insect circadian clocks. Mol Biol Evol. 2007 Apr; 24(4):948-55. 
View in: PubMed

Zhu H, Yuan Q, Briscoe AD, Froy O, Casselman A, Reppert SM. The two CRYs of the butterfly. Curr Biol. 2005 Dec 6; 15(23):R953-4. 
View in: PubMed

Sauman I, Briscoe AD, Zhu H, Shi D*, Froy O, Stalleicken J, Yuan Q, Casselman A, Reppert SM. Connecting the navigational clock to sun compass input in monarch butterfly brain. Neuron. 2005 May 5; 46(3):457-67. 
View in: PubMed

Chang DC, McWatters HG, Williams JA, Gotter AL, Levine JD, Reppert SM. Constructing a feedback loop with circadian clock molecules from the silkmoth, Antheraea pernyi. J Biol Chem. 2003 Oct 3; 278(40):38149-58. 
View in: PubMed

Chang DC, Reppert SM. A novel C-terminal domain of drosophila PERIOD inhibits dCLOCK:CYCLE-mediated transcription. Curr Biol. 2003 Apr 29; 13(9):758-62. 
View in: PubMed

Froy O, Chang DC, Reppert SM. Redox potential: differential roles in dCRY and mCRY1 functions. Curr Biol. 2002 Jan 22; 12(2):147-52. 
View in: PubMed

Chang DC, Reppert SM. The circadian clocks of mice and men. Neuron. 2001 Mar; 29(3):555-8. 
View in: PubMed

 

Student Publications from the Reppert Lab at MGH/Harvard Medical School

Students:

    Mark J. Zylka, PhD from Harvard Medical School

    Alfred L. Roca, PhD from Harvard Medical School

    Tony Tsai*, undergraduate, Harvard University

    David K. Welsh, MD/PhD from Harvard Medical School

 

Zylka MJ, Reppert SM. Discovery of a putative heme-binding protein family (SOUL/HBP) by two-tissue suppression subtractive hybridization and database searches. Brain Res Mol Brain Res. 1999 Dec 10; 74(1-2):175-81. 
View in: PubMed

Kume K, Zylka MJ, Sriram S, Shearman LP, Weaver DR, Jin X, Maywood ES, Hastings MH, Reppert SM. mCRY1 and mCRY2 are essential components of the negative limb of the circadian clock feedback loop. Cell. 1999 Jul 23; 98(2):193-205. 
View in: PubMed

Shearman LP, Zylka MJ, Reppert SM, Weaver DR. Expression of basic helix-loop-helix/PAS genes in the mouse suprachiasmatic nucleus. Neuroscience. 1999 Mar; 89(2):387-97. 
View in: PubMed

Jin X, Shearman LP, Weaver DR, Zylka MJ, de Vries GJ, Reppert SM. A molecular mechanism regulating rhythmic output from the suprachiasmatic circadian clock. Cell. 1999 Jan 8; 96(1):57-68. 
View in: PubMed

Zylka MJ, Shearman LP, Levine JD, Jin X, Weaver DR, Reppert SM. Molecular analysis of mammalian Timeless. Neuron. 1998 Nov; 21(5):1115-22. 
View in: PubMed

Shearman LP, Zylka MJ, Weaver DR, Kolakowski LF, Reppert SM. Two period homologs: circadian expression and photic regulation in the suprachiasmatic nuclei. Neuron. 1997 Dec; 19(6):1261-9. 
View in: PubMed

Sauman I, Tsai T*, Roca AL, Reppert SM. Period protein is necessary for circadian control of egg hatching behavior in the silkmoth Antheraea pernyi. Neuron. 1996 Nov; 17(5):901-9. 
View in: PubMed

Roca AL, Godson C, Weaver DR, Reppert SM. Structure, characterization, and expression of the gene encoding the mouse Mel1a melatonin receptor. Endocrinology. 1996 Aug; 137(8):3469-77. 
View in: PubMed

Welsh DK, Reppert SM. Gap junctions couple astrocytes but not neurons in dissociated cultures of rat suprachiasmatic nucleus. Brain Res. 1996 Jan 8; 706(1):30-6. 
View in: PubMed

Slaugenhaupt SA, Roca AL, Liebert CB, Altherr MR, Gusella JF, Reppert SM. Mapping of the gene for the Mel1a-melatonin receptor to human chromosome 4 (MTNR1A) and mouse chromosome 8 (Mtnr1a). Genomics. 1995 May 20; 27(2):355-7. 
View in: PubMed

Weaver DR, Roca AL, Reppert SM. c-fos and jun-B mRNAs are transiently expressed in fetal rodent suprachiasmatic nucleus following dopaminergic stimulation. Brain Res Dev Brain Res. 1995 Apr 18; 85(2):293-7. 
View in: PubMed

Welsh DK, Logothetis DE, Meister M, Reppert SM. Individual neurons dissociated from rat suprachiasmatic nucleus express independently phased circadian firing rhythms. Neuron. 1995 Apr; 14(4):697-706. 
View in: PubMed

Reppert SM, Tsai T*, Roca AL, Sauman I. Cloning of a structural and functional homolog of the circadian clock gene period from the giant silkmoth Antheraea pernyi. Neuron. 1994 Nov; 13(5):1167-76. View in: PubMed

Roca AL, Weaver DR, Reppert SM. Serotonin receptor gene expression in the rat suprachiasmatic nuclei. Brain Res. 1993 Apr 9; 608(1):159-65. View in: PubMed

Nadakavukaren JJ, Welsh DK, Reppert SM. Aluminum fluoride reveals a phosphoinositide system within the suprachiasmatic region of rat hypothalamus. Brain Res. 1990 Jan 22; 507(2):181-8. View in: PubMed

 

Student Publications from the Schafer Lab (established at UMMS in 2015)

Current Student:

      Jeffrey Frost                                       Neuroscience Program

 

Student Publications from the Weaver Lab (established at UMMS in 2001)

Graduates:

      Elizabeth A. Yu, M.D., Ph.D.         2013    MD/PhD Program

Current Students:

      Evelyn Erickson                                   Neuroscience Program

Other Students:

      Kaz K. Machida                             2006    M.S., Neuroscience Program

      Kyle K. Rumery was an undergraduate at St. Olaf College at the time of his participation in the UMMS Summer Undergraduate Research Program.

 

Punia S, Rumery KK* , Yu EA, Lambert CM, Notkins AL, Weaver DR. Disruption of gene expression rhythms in mice lacking secretory vesicle proteins IA-2 and IA-2ß. Am J Physiol Endocrinol Metab. 2012 Sep 15; 303(6):E762-76. 
View in: PubMed

Yu EA, Weaver DR. Disrupting the circadian clock: gene-specific effects on aging, cancer, and other phenotypes. Aging (Albany NY). 2011 May; 3(5):479-93. 
View in: PubMed

Etchegaray JP, Yu EA, Indic P, Dallmann R, Weaver DR. Casein kinase 1 delta (CK1delta) regulates period length of the mouse suprachiasmatic circadian clock in vitro. PLoS One. 2010; 5(4):e10303. 
View in: PubMed

Etchegaray JP, Machida KK, Noton E, Constance CM, Dallmann R, Di Napoli MN, DeBruyne JP, Lambert CM, Yu EA, Reppert SM, Weaver DR. Casein kinase 1 delta regulates the pace of the mammalian circadian clock. Mol Cell Biol. 2009 Jul; 29(14):3853-66. 
View in: PubMed

Lambert CM, Machida KK, Smale L, Nunez AA, Weaver DR. Analysis of the prokineticin 2 system in a diurnal rodent, the unstriped Nile grass rat (Arvicanthis niloticus). J Biol Rhythms. 2005 Jun; 20(3):206-18. 
View in: PubMed

 

Student publications from the Xiang Lab (established at UMMS in 2012)

Current Student:

      Kendra Takle                                             Neuroscience Program

Yang L, Li R, Kaneko T, Takle K, Morikawa RK, Essex L, Wang X, Zhou J, Emoto K, Xiang Y, Ye B. Trim9 regulates activity-dependent fine-scale topography in Drosophila. Curr Biol. 2014 May 5;24(9):1024-30. doi: 10.1016/j.cub.2014.03.041. Epub 2014 Apr 17. PubMed PMID: 24746793; PubMed Central PMCID: PMC4030378.

 

Student Publications of Faculty Alumni

 

Student publications from the Tzumin Lee lab (Neurobiology Department member 2005- 2009)

PhD graduates:

      Sen-Lin Lai                                    2007    Neuroscience Program

      Shun-Jen (Jacob) S. Yang               2008    Neuroscience Program

      Lei Shi                                           2010    Neuroscience Program

      Sue-Wei Lin                                   2011    Neuroscience Program

      Hui-Min Chen                                 2015    Neuroscience Program

 

Chen HM, Huang Y, Pfeiffer BD, Yao X, Lee T. An enhanced gene targeting toolkit for Drosophila: Golic+. Genetics. 2015 Mar;199(3):683-94. doi: 10.1534/genetics.114.173716. Epub 2015 Jan 2. PubMed PMID: 25555988; PubMed Central PMCID: PMC4349064.

Port F, Chen HM, Lee T, Bullock SL. Optimized CRISPR/Cas tools for efficient germline and somatic genome engineering in Drosophila. Proc Natl Acad Sci U S A. 2014 Jul 22;111(29):E2967-76. doi: 10.1073/pnas.1405500111. Epub 2014 Jul 7. PubMed PMID: 25002478; PubMed Central PMCID: PMC4115528.

Lin S, Marin EC, Yang CP, Kao CF, Apenteng BA, Huang Y, O'Connor MB, Truman JW, Lee T. Extremes of lineage plasticity in the Drosophila brain. Curr Biol. 2013 Oct 7;23(19):1908-13. doi: 10.1016/j.cub.2013.07.074. Epub 2013 Sep 19. PubMed PMID: 24055154; PubMed Central PMCID: PMC3902790.

Lin S, Kao CF, Yu HH, Huang Y, Lee T. Lineage analysis of Drosophila lateral antennal lobe neurons reveals notch-dependent binary temporal fate decisions. PLoS Biol. 2012;10(11):e1001425. doi: 10.1371/journal.pbio.1001425. Epub 2012 Nov 20. PubMed PMID: 23185131; PubMed Central PMCID: PMC3502534.

Shi L, Lee T. Molecular diversity of Dscam and self-recognition. Adv Exp Med Biol. 2012;739:262-75. doi: 10.1007/978-1-4614-1704-0_17. Review. PubMed PMID: 22399408.

Lin S, Lee T. Generating neuronal diversity in the Drosophila central nervous system. Dev Dyn. 2012 Jan;241(1):57-68. doi: 10.1002/dvdy.22739. Epub 2011 Sep19. Review. PubMed PMID: 21932323.

Pitman JL, Huetteroth W, Burke CJ, Krashes MJ, Lai SL, Lee T, Waddell S. A pair of inhibitory neurons are required to sustain labile memory in the Drosophila mushroom body. Curr Biol. 2011 May 24;21(10):855-61. doi: 10.1016/j.cub.2011.03.069. Epub 2011 Apr 28. PubMed PMID: 21530258; PubMed Central PMCID: PMC3111962.

Lin S, Huang Y, Lee T. Nuclear receptor unfulfilled regulates axonal guidance and cell identity of Drosophila mushroom body neurons. PLoS One. 2009 Dec 22;4(12):e8392. doi: 10.1371/journal.pone.0008392. PubMed PMID: 20027309; PubMed  Central PMCID: PMC2793019.

Lin S, Lai SL, Yu HH, Chihara T, Luo L, Lee T. Lineage-specific effects of Notch/Numb signaling in post-embryonic development of the Drosophila brain. Development. 2010 Jan;137(1):43-51. doi: 10.1242/dev.041699. PubMed PMID: 20023159; PubMed Central PMCID: PMC2796933.

Yu HH, Chen CH, Shi L, Huang Y, Lee T. Twin-spot MARCM to reveal the developmental origin and identity of neurons. Nat Neurosci. 2009 Jul;12(7):947-53. doi: 10.1038/nn.2345. Epub 2009 Jun 14. PubMed PMID: 19525942;  PubMed Central PMCID: PMC2701974.

Yu HH, Yang JS, Wang J, Huang Y, Lee T. Endodomain diversity in the Drosophila Dscam and its roles in neuronal morphogenesis. J Neurosci. 2009 Feb 11;29(6):1904-14. doi: 10.1523/JNEUROSCI.5743-08.2009. PubMed PMID: 19211897; PubMed Central PMCID: PMC2671081.

Awasaki T, Lai SL, Ito K, Lee T. Organization and postembryonic development of glial cells in the adult central brain of Drosophila. J Neurosci. 2008 Dec 17;28(51):13742-53. doi: 10.1523/JNEUROSCI.4844-08.2008. PubMed PMID: 19091965.

Yang JS, Bai JM, Lee T. Dynein-dynactin complex is essential for dendritic restriction of TM1-containing Drosophila Dscam. PLoS One. 2008;3(10):e3504. doi:  10.1371/journal.pone.0003504. Epub 2008 Oct 23. PubMed PMID: 18946501; PubMed Central PMCID: PMC2566808.

Lai SL, Awasaki T, Ito K, Lee T. Clonal analysis of Drosophila antennal lobe  neurons: diverse neuronal architectures in the lateral neuroblast lineage. Development. 2008 Sep;135(17):2883-93. doi: 10.1242/dev.024380. Epub 2008 Jul 24. PubMed PMID: 18653555.

Shi L, Yu HH, Yang JS, Lee T. Specific Drosophila Dscam juxtamembrane variants control dendritic elaboration and axonal arborization. J Neurosci. 2007  Jun 20;27(25):6723-8. PubMed PMID: 17581959.

Shi L, Lin S, Grinberg Y, Beck Y, Grozinger CM, Robinson GE, Lee T. Roles of Drosophila Kruppel-homolog 1 in neuronal morphogenesis. Dev Neurobiol. 2007 Oct;67(12):1614-26. PubMed PMID: 17562531.

Soba P, Zhu S, Emoto K, Younger S, Yang SJ, Yu HH, Lee T, Jan LY, Jan YN. Drosophila sensory neurons require Dscam for dendritic self-avoidance and proper dendritic field organization. Neuron. 2007 May 3;54(3):403-16. PubMed PMID: 17481394; PubMed Central PMCID: PMC1963441.

Zhu S, Lin S, Kao CF, Awasaki T, Chiang AS, Lee T. Gradients of the Drosophila Chinmo BTB-zinc finger protein govern neuronal temporal identity. Cell. 2006 Oct 20;127(2):409-22. PubMed PMID: 17055440.

Lai SL, Lee T. Genetic mosaic with dual binary transcriptional systems in Drosophila. Nat Neurosci. 2006 May;9(5):703-9. Epub 2006 Apr 2. PubMed PMID: 16582903.

Wang J, Lee CH, Lin S, Lee T. Steroid hormone-dependent transformation of polyhomeotic mutant neurons in the Drosophila brain. Development. 2006 Apr;133(7):1231-40. Epub 2006 Feb 22. PubMed PMID: 16495309.

Zheng X, Zugates CT, Lu Z, Shi L, Bai JM, Lee T. Baboon/dSmad2 TGF-beta signaling is required during late larval stage for development of adult-specific neurons. EMBO J. 2006 Feb 8;25(3):615-27. Epub 2006 Jan 26. PubMed PMID: 16437159; PubMed Central PMCID: PMC1383542.

Wang J, Ma X, Yang JS, Zheng X, Zugates CT, Lee CH, Lee T. Transmembrane/ juxtamembrane domain-dependent Dscam distribution and function during mushroom body neuronal morphogenesis. Neuron. 2004 Sep 2;43(5):663-72. PubMed PMID: 15339648.

 

Student publications from the Lois Lab (Neurobiology Department member 2010- 2015)

Current student:

       Ting-Hao Huang                                      Neuroscience Program

 

Student publications from the Treistman Lab (Neurobiology Department member 2001- 2005)

Ph.D. graduates from UMass Medical School:

      John J. Crowley                            2003    Neuroscience Program

      Keith Tully                                   2004    Neuroscience Program

      Paula L. Feinberg-Zadek               2005    Neuroscience Program

      Patricia Wynne                             2008    Neuroscience Program

 

Velazquez-Marrero C, Wynne P, Bernardo A, Palacio S, Martin G, Treistman SN. The relationship between duration of initial alcohol exposure and persistence of molecular tolerance is markedly nonlinear. J Neurosci. 2011 Feb 16;31(7):2436-46. doi: 10.1523/JNEUROSCI.5429-10.2011. PubMed PMID: 21325511; PubMed Central PMCID: PMC3758537.

Wynne PM, Puig SI, Martin GE, Treistman SN. Compartmentalized beta subunit distribution determines characteristics and ethanol sensitivity of somatic, dendritic, and terminal large-conductance calcium-activated potassium channels in the rat central nervous system. J Pharmacol Exp Ther. 2009 Jun;329(3):978-86. doi: 10.1124/jpet.108.146175. Epub 2009 Mar 25. PubMed PMID: 19321803; PubMed Central PMCID: PMC2683776.

Pietrzykowski AZ, Friesen RM, Martin GE, Puig SI, Nowak CL, Wynne PM, Siegelmann HT, Treistman SN. Posttranscriptional regulation of BK channel splice variant stability by miR-9 underlies neuroadaptation to alcohol. Neuron. 2008 Jul 31;59(2):274-87. doi: 10.1016/j.neuron.2008.05.032. PubMed PMID: 18667155; PubMed Central PMCID: PMC2714263.

Feinberg-Zadek PL, Martin G, Treistman SN. BK channel subunit composition modulates molecular tolerance to ethanol. Alcohol Clin Exp Res. 2008 Jul;32(7):1207-16. doi: 10.1111/j.1530-0277.2008.00704.x. PubMed PMID: 18537940.

Feinberg-Zadek PL, Treistman SN. Beta-subunits are important modulators of the acute response to alcohol in human BK channels. Alcohol Clin Exp Res. 2007 May;31(5):737-44. Epub 2007 Mar 28. PubMed PMID: 17391339.

Crowley JJ, Treistman SN, Dopico AM. Distinct structural features of phospholipids differentially determine ethanol sensitivity and basal function of BK channels. Mol Pharmacol. 2005 Jul;68(1):4-10. Epub 2005 Apr 22. PubMed PMID: 15849354.

Newton PM, Tully K, McMahon T, Connolly J, Dadgar J, Treistman SN, Messing RO. Chronic ethanol exposure induces an N-type calcium channel splice variant with altered channel kinetics. FEBS Lett. 2005 Jan 31;579(3):671-6. PubMed PMID: 15670827.

Yuan C, O'Connell RJ, Feinberg-Zadek PL, Johnston LJ, Treistman SN. Bilayer thickness modulates the conductance of the BK channel in model membranes. Biophys J. 2004 Jun;86(6):3620-33. PubMed PMID: 15189859; PubMed Central PMCID: PMC1304264.

Tully K, Treistman SN. Distinct intracellular calcium profiles following influx through N- versus L-type calcium channels: role of Ca2+-induced Ca2+ release. J Neurophysiol. 2004 Jul;92(1):135-43. Epub 2004 Mar 3. PubMed PMID: 14999048.

Crowley JJ, Treistman SN, Dopico AM. Cholesterol antagonizes ethanol potentiation of human brain BKCa channels reconstituted into phospholipid bilayers. Mol Pharmacol. 2003 Aug;64(2):365-72. PubMed PMID: 12869641.

Tully K, Kupfer D, Dopico AM, Treistman SN. A plasticizer released from IV drip chambers elevates calcium levels in neurosecretory terminals. Toxicol Appl Pharmacol. 2000 Nov 1;168(3):183-8. PubMed PMID: 11042090.

 

Student publications from Waddell Lab (Neurobiology Department member 2001- 2011)

Ph.D. graduates from UMass Medical School:

      Alex C. Keene                                     2006    Neuroscience Program

      Michael Krashes                                  2009    Neuroscience Program

      Shamik DasGupta                                2009    Neuroscience Program

      Paola Perrat                                       2012    Neuroscience Program

      Christopher Burke                               2013    Neuroscience Program

 

Das G, Klappenbach M, Vrontou E, Perisse E, Clark CM, Burke CJ, Waddell S. Drosophila learn opposing components of a compound food stimulus. Curr Biol. 2014 Aug 4;24(15):1723-30. doi: 10.1016/j.cub.2014.05.078. Epub 2014 Jul 17. PubMed PMID: 25042590; PubMed Central PMCID: PMC4131107.

Perisse E, Burke C, Huetteroth W, Waddell S. Shocking revelations and saccharin sweetness in the study of Drosophila olfactory memory. Curr Biol. 2013 Sep 9;23(17):R752-63. doi: 10.1016/j.cub.2013.07.060. Review. PubMed PMID: 24028959; PubMed Central PMCID: PMC3770896.

Perrat PN, DasGupta S, Wang J, Theurkauf W, Weng Z, Rosbash M, Waddell S. Transposition-driven genomic heterogeneity in the Drosophila brain. Science. 2013 Apr 5;340(6128):91-5. doi: 10.1126/science.1231965. PubMed PMID: 23559253; PubMed Central PMCID: PMC3887341.

Burke CJ, Huetteroth W, Owald D, Perisse E, Krashes MJ, Das G, Gohl D, Silies M, Certel S, Waddell S. Layered reward signalling through octopamine and dopamine in Drosophila. Nature. 2012 Dec 20;492(7429):433-7. doi: 10.1038/nature11614. Epub 2012 Oct 28. PubMed PMID: 23103875; PubMed Central PMCID: PMC3528794.

Krashes MJ, Waddell S. Drosophila aversive olfactory conditioning. Cold Spring Harb Protoc. 2011 May 1;2011(5):pdb.prot5608. doi: 10.1101/pdb.prot5608. PubMed PMID: 21536768.

Krashes MJ, Waddell S. Drosophila appetitive olfactory conditioning. Cold Spring Harb Protoc. 2011 May 1;2011(5):pdb.prot5609. doi: 10.1101/pdb.prot5609. PubMed PMID: 21536767.

Pitman JL, Huetteroth W, Burke CJ, Krashes MJ, Lai SL, Lee T, Waddell S. A pair of inhibitory neurons are required to sustain labile memory in the Drosophila mushroom body. Curr Biol. 2011 May 24;21(10):855-61. doi: 10.1016/j.cub.2011.03.069. Epub 2011 Apr 28. PubMed PMID: 21530258; PubMed Central PMCID: PMC3111962.

Burke CJ, Waddell S. Remembering nutrient quality of sugar in Drosophila. Curr Biol. 2011 May 10;21(9):746-50. doi: 10.1016/j.cub.2011.03.032. Epub 2011 Apr 21. PubMed PMID: 21514159; PubMed Central PMCID: PMC3094154.

Koon AC, Ashley J, Barria R, DasGupta S, Brain R, Waddell S, Alkema MJ, Budnik V. Autoregulatory and paracrine control of synaptic and behavioral plasticity by octopaminergic signaling. Nat Neurosci. 2011 Feb;14(2):190-9. doi: 10.1038/nn.2716. Epub 2010 Dec 26. PubMed PMID: 21186359; PubMed Central PMCID: PMC3391700.

Krashes MJ, DasGupta S, Vreede A, White B, Armstrong JD, Waddell S. A neural circuit mechanism integrating motivational state with memory expression in Drosophila. Cell. 2009 Oct 16;139(2):416-27. doi: 10.1016/j.cell.2009.08.035. PubMed PMID: 19837040; PubMed Central PMCID: PMC2780032.

Pitman JL, DasGupta S, Krashes MJ, Leung B, Perrat PN, Waddell S. There are many ways to train a fly. Fly (Austin). 2009 Jan-Mar;3(1):3-9. Epub 2009 Jan 29.  Review. PubMed PMID: 19164943; PubMed Central PMCID: PMC2814444.

DasGupta S, Waddell S. Learned odor discrimination in Drosophila without combinatorial odor maps in the antennal lobe. Curr Biol. 2008 Nov 11;18(21):1668-74. doi: 10.1016/j.cub.2008.08.071. Epub 2008 Oct 23. PubMed PMID: 18951022; PubMed Central PMCID: PMC2602956.

Krashes MJ, Waddell S. Rapid consolidation to a radish and protein synthesis-dependent long-term memory after single-session appetitive olfactory conditioning in Drosophila. J Neurosci. 2008 Mar 19;28(12):3103-13. doi: 10.1523/JNEUROSCI.5333-07.2008. PubMed PMID: 18354013; PubMed Central PMCID: PMC2516741.

Krashes MJ, Waddell S. Drosophila memory: will Orb(2) predict the future? Curr Biol. 2008 Jan 22;18(2):R74-6. doi: 10.1016/j.cub.2007.11.053. PubMed PMID: 18211845.

Rickmyre JL, Dasgupta S, Ooi DL, Keel J, Lee E, Kirschner MW, Waddell S, Lee LA. The Drosophila homolog of MCPH1, a human microcephaly gene, is required for genomic stability in the early embryo. J Cell Sci. 2007 Oct 15;120(Pt 20):3565-77. Epub 2007 Sep 25. PubMed PMID: 17895362.

Keene AC, Waddell S. Drosophila olfactory memory: single genes to complex neural circuits. Nat Rev Neurosci. 2007 May;8(5):341-54. Review. PubMed PMID: 17453015.

Krashes MJ, Keene AC, Leung B, Armstrong JD, Waddell S. Sequential use of mushroom body neuron subsets during drosophila odor memory processing. Neuron. 2007 Jan 4;53(1):103-15. PubMed PMID: 17196534; PubMed Central PMCID: PMC1828290.

Keene AC, Krashes MJ, Leung B, Bernard JA, Waddell S. Drosophila dorsal paired medial neurons provide a general mechanism for memory consolidation. Curr  Biol. 2006 Aug 8;16(15):1524-30. PubMed PMID: 16890528.

Yu D, Keene AC, Srivatsan A, Waddell S, Davis RL. Drosophila DPM neurons form a delayed and branch-specific memory trace after olfactory classical conditioning. Cell. 2005 Dec 2;123(5):945-57. PubMed PMID: 16325586.

Keene AC, Waddell S. Drosophila memory: dopamine signals punishment? Curr Biol. 2005 Nov 22;15(22):R932-4. Review. Erratum in: Curr Biol. 2005 Dec 6;15(23):2176. PubMed PMID: 16303554.

Keene AC, Stratmann M, Keller A, Perrat PN, Vosshall LB, Waddell S. Diverse odor-conditioned memories require uniquely timed dorsal paired medial neuron output. Neuron. 2004 Oct 28;44(3):521-33. PubMed PMID: 15504331.

 

Student publications from the Yoshihara Lab (Neurobiology Department member 2006- 2013)

MD/PhD Graduate:

      Thomas Flood                               2013    MD/PhD Program

 

Flood TF, Gorczyca M, White BH, Ito K, Yoshihara M. A large-scale behavioral screen to identify neurons controlling motor programs in the Drosophila brain. G3 (Bethesda). 2013 Oct 3;3(10):1629-37. doi: 10.1534/g3.113.006205. PubMed PMID: 23934998; PubMed Central PMCID: PMC3789788.

Flood TF, Iguchi S, Gorczyca M, White B, Ito K, Yoshihara M. A single pair of interneurons commands the Drosophila feeding motor program. Nature. 2013 Jul 4;499(7456):83-7. doi: 10.1038/nature12208. Epub 2013 Jun 9. PubMed PMID: 23748445; PubMed Central PMCID: PMC3727048.

▴ Back To Top