National Research Collaborations

The Meyers Primary Care Institute leverages the research capabilities of a collective network of organizations committed to advancing clinical practice through quality research.

Below is a list of research networks we are currently affiliated with.

Accelerating Change and Transformation in Organizations and Networks (ACTION II)

ACTION II is a model of field-based research designed to promote innovation in healthcare delivery by accelerating the diffusion of research into practice. The ACTION II network includes 17 large partnerships and more than 350 collaborating organizations that provide healthcare to an estimated 50 percent of the U.S. population.

Principal Investigator: Julie Schmittdiel, PhD, Kaiser Permanente, Division of Research 
MPCI Lead / Contact: Susan Andrade, ScD

Cancer Research Network (CRN) CRN Logo

The CRN supports and facilitates cancer research in non-profit integrated healthcare delivery settings that improves knowledge about cancer etiology, prevention, early detection, treatment and prognosis, and that decreases the burden of cancer across the cancer care spectrum. This work is conducted across the healthcare settings of 9 members of the HMO Research Network, providing access to approximately 9 million enrollees.

Principal Investigator: Lawrence Kushi, ScD, Kaiser Permanente, Division of Research
MPCI Lead / Contact: Kathleen Mazor, EdD

Cardiovascular Research Network (CVRN) CVRN Logo

The CVRN is a national collaborative that leverages the expertise, populations, and data sources from a consortium of 14 geographically diverse health plans across the United States. The goals of the CVRN are to provide robust cardiovascular disease data and promote research on clinical practice, quality of care, and determinants of disease. The CVRN is funded by the National Heart, Lung and Blood Institute.

Principal Investigator: Alan Go, MD, Kaiser Permanente, Division of Research
MPCI Lead / Contact: Jerry H. Gurwitz, MD  

Developing Evidence to Improve Decisions about Effectiveness (DEcIDE) Networks

The DEcIDE I Network is a collection of research centers created by the Agency for Healthcare Research and Quality. These centers offer task order opportunities using health plans’ defined populations, providers, delivery systems, and unique data resources to develop information about therapeutic effectiveness within typical clinical settings.

The DEcIDE II Network supports the Agency for Healthcare Research and Quality’s response to the Medicare Modernization Act's mandates for comparative effectiveness and safety research. The Network develops scientific evidence and methodologies about the outcomes, comparative clinical effectiveness, safety, and appropriateness of healthcare items and services for improving the quality, effectiveness, and efficiency of healthcare.

Principal Investigator: Richard Platt, MD, MSc, Harvard Pilgrim Healthcare Institute 
MPCI Lead / Contact: Susan Andrade, ScD

HMO Research Network (HMORN) HMORN Logo Small

The HMORN is a consortium of 18 healthcare delivery organizations with defined patient populations and formal, recognized, research capabilities. The HMORN improves individual and population health through research that connects the resources and capabilities of learning healthcare systems.

MPCI Governing Board Member: Jerry H. Gurwitz, MD

Medical Exposure in Pregnancy Risk Evaluation Program (MEPREP)

MEPREP is a collaboration between the U.S. Food and Drug Administration, 11 HMO Research Network sites, and Vanderbilt University. The program is the largest of its kind that is developing the infrastructure to enhance the ability to study the effects of medication exposure during pregnancy on the fetus by creating and maintaining linked data on mothers and infants. The 11 participating MEPREP sites have healthcare information for approximately 1 million births over a seven year period.

Principal Investigator: Richard Platt, MD, MSc, Harvard Pilgrim Healthcare Institute
MPCI Lead / Contact: Susan Andrade, ScD

Mini-Sentinel Mini Sentinel Logo Small

The Sentinel initiatives are funded by the U.S. Food and Drug Administration and include at least 13 care organizations covering more than 12 million lives. The Sentinel project goal is to create a linked and sustainable system that will draw on existing automated healthcare data from multiple sources to actively monitor the safety of medical products. The Mini-Sentinal is a single coordinating center for the rapid assessment of suspected associations between medical products and adverse health outcomes.

Principal Investigator: Richard Platt, MD, MSc, Harvard Pilgrim Healthcare Institute 
MPCI Lead / Contact: Susan Andrade, ScD

We believe in strength in numbers, and our work is underpinned by a spirit of collaboration and consultation. This benefits the health and wellbeing of our community, and beyond.

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