Section: Rotations

Alan Rothman, M.D.

Academic Role: Professor

Faculty Appointment(s) In:
   Infectious Diseases and Immunology
   Medicine

Other Affiliation(s):
   Center for AIDS Research
   Center for Infectious Disease and Vaccine Research
   Clinical and Population Health Research
   Program in Immunology and Virology

Potential Rotation Projects

• Flavivirus-specific T lymphocytes- isolation of T lymphocytes (human or murine) with novel specificities for epitopes of dengue virus or hepatitis C virus; functional characterization of T cell effector responses; quantitation of epitope-specific CD4 and/or CD8 T cells; molecular analysis of virus-specific T cell receptor genes



• In vitro replication of dengue virus- viral binding; viral replication in primary human cells



• Flavivirus proteins- cloning and expression of flavivirus genes; analysis of protein function in vitro

Office: S6-755a
Phone: 508-856-6976
Fax: 508-856-4890
E-mail: Alan.Rothman@umassmed.edu
Keywords: T lymphocytes, Biodefense, Viral Pathogenesis, Emerging Infectious Diseases, Viral Infections and Immunity

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