Section: Rotations

Postdoctoral Position Available

Evelyn Kurt-Jones, Ph.D.

Academic Role: Professor

Faculty Appointment(s) In:
   Medicine

Other Affiliation(s):
   Center for AIDS Research
   Infectious Diseases and Immunology
   Program in Immunology and Virology

Potential Rotation Projects

1. Expression of Toll-like receptors: Patterns of TLR expression in normal cells. Control of TLR receptor expression by environmental factors and cytokines. TLR expression in diseased tissues.



2. Role of TLRs in disease pathogenesis: Use of knockout and genetically defined animals to study the role of TLRs in the control of bacterial or viral diseases.



3. Structure-function studies of TLR signaling: Assessing the signaling activity of wild type and mutant TLRs (altered by site-directed mutageneis) using transient transfection and luciferase reporter gene analysis.

Office: LRB 226
Phone: 508-856-3531
Fax: 508-856-6176
E-mail: Evelyn.Kurt-Jones@umassmed.edu
Keywords: Immunology, Virology, Signal Transduction

More on Evelyn Kurt-Jones' Research Research | Publications | Rotations View All Sections on One Page

Postdoctoral Position Available We are seeking a post-doctoral fellow to study toll/interleukin 1 receptors and their role in inflammatory disease pathogenesis using human cells and mouse models. Candidates should have a Ph.D. or M.D. degree, or have completed degree requirements. Experience in immunology, molecular biology and/or biochemistry and publication of papers in the areas of cytokine biology, receptor biochemistry and/or cell signaling required.