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Timothy Kowalik, Ph.D.
Academic Role: Associate Professor
Faculty Appointment(s) In:
Molecular Genetics and Microbiology
Other Affiliation(s):
Center for AIDS Research
Interdisciplinary Graduate Program
Program in Immunology and Virology
Recent Publications
Rogoff, H.A., Pickering, M.T., Frame, F.M., Sanchez, Y., Jones, S., and Kowalik, T.F. 2004. Apoptosis associated with deregulated E2F activity is dependent on E2F1 and Atm/Nbs1/Chk2. Mol. Cell. Biol., 24, 2968-2977. Pubmed Article
Journal Article
Castillo, J.P., Frame, F.M., Rogoff, H.A., Pickering, M.T., and Kowalik, T.F. 2005. HCMV IE1-72 activates ATM and a p53/p21-mediated growth arrest response. J. Virol. 79, 11467-11475. Pubmed Article Journal Article
Pickering M.T. and Kowalik, T.F. 2006. Rb inactivation leads to E2F1-mediated DNA double strand break accumulation. Oncogene, 25, 746-755. Pubmed Article Journal Article
Frame, F.M., Rogoff, H.A., Pickering, M.T., Cress, W.D. and Kowalik, T.F. 2006. E2F1 induces Mre11 foci formation and a cell cycle checkpoint response in human fibroblasts. Oncogene, 25, 3258-3266. Pubmed Article Journal Article
Office: S5-216
Phone: 508-856-6035
E-mail: Timothy.Kowalik@umassmed.edu
Keywords:
Cancer Biology,
Virology,
Gene Expression
Postdoctoral Position Available
Postdoctoral positions are available to study the relationship(s) between the Rb/E2F proliferation pathway and p53-dependent apoptosis. Areas of investigation include understanding why E2F1 is unique among the E2F family in its strong apoptosis signaling ability and determining the pathways that lead from E2F1 activation to cell death. Fellows will be associated with a highly motivated and interactive group of researchers studying aspects of cell cycle, apoptosis signaling and cancer using cell culture, virology and animal models.
If interested, please contact:
Timothy Kowalik
Department of Molecular Genetics and Microbiology
University of Massachusetts Medical School
55 Lake Avenue North
Worcester, MA 01655
The University of Massachusetts Medical School is an Affirmative Action / Equal Opportunity Employer.
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