Leslie J. Berg , Ph.D. (Pathology)
Immunology Program Director
Signal transduction proteins involved in T-cell development and activation.
Trudy G.Morrison, Ph.D. (Microbiology & Physiological Systems)
Virology Program Director
Glycoprotein processing and assembly; mechanisms of paramyxovirus membrane fusion.
Beth McCormick, Ph.D. (Microbiology & Physiological Systems)
Bacterial Pathnogenenisis Program Director
Investigation of the host-pathogen interface at mucosal surfaces.
Lawrence J. Stern, Ph.D. (Pathology)
Immunology and Microbiology Committee Chair
Molecular recognition in the immune system.
|Jeffrey Bailey, MD, Ph.D.(Division of Transfusion Medicine, Program for Bioinformatics and Integrative Biology)|
Infectious disease genetics focused on copy number variation and malaria.
|Samuel L. Behar, M.D., Ph.D. (Microbiology and Physiological Systems)|
Innate and acquired immunity to Mycobacterium tuberculosis, with an emphasis on understanding mechanisms of host protection against disease.
Rita Bortell, Ph.D. (Medicine, Diabetes)
Pathogenesis of autoimmune diabetes.
|Abraham Brass, MD, Ph.D. (Microbiology and Physiological Systems)|
Our lab studies host-viral interactions and the IFITM family of anti-viral proteins
|Michael Brehm, Ph.D. (Medicine, Diabetes)|
Antiviral immunity, development of humanized mouse models.
Francis Ka-Ming Chan, Ph.D. (Pathology)
Analysis of TNF receptor signaling in healthy and diseased immune systems.
Jason J. Chen, Ph.D. (Medicine)
Cell cycle checkpoints and apoptosis of cells expressing papillomavirus oncogenes.
Paul R. Clapham, Ph.D. (Molecular Medicine)
HIV receptors and cellular tropisms.
|Richard Dutton, Ph.D. (Pathology)|
Generation and function of CD8 effector and memory T cells.
Francis A. Ennis, MD (Medicine)
Clinical and laboratory studies on the immune response of host to virus infections, emphasizing the role of cellular responses in viral infections.
Robert W. Finberg, MD (Medicine)
Host cell surface proteins and viruses; Cellular activation mediated by cell surface proteins.
Kate Fitzgerald, Ph.D. (Medicine)
Anti-viral innate immune signaling.
| ||Terence Flotte, MD (Pediatrics, Microbiology & Physiological Systems , Dean's Office)|
Adeno-associated virus vectors for gene therapy of single gene disorders.
|Guangping Gao, Ph.D. (Gene Therapy)|
Parvovirus evolution, viral-host interactions and vectorology for gene transfer.
Manuel Garber, Ph.D. (Program in Molecular Medicine)
|Ricardo Gazzinelli, D.Sc., D.V.M (Infectious Diseases and Immunology Medicine)|
Cognate innate immune receptors and development of vaccines for protozoan parasites.
Rachel M. Gerstein, Ph.D. (Microbiology & Physiological Systems)
B cell development, including aging; origins of B cell lymphoma; humoral immunity to bacterial pathogens
| ||Richard Glew, MD (Medicine, Infectious Diseases and Immunology)|
Vice Chair of Medicine for Undergraduate Education and Faculty Affairs
Jon D. Goguen, Ph.D. (Microbiology & Physiological Systems)
Function and regulation of virulence determinants in Yersinia pestis.
Douglas T. Golenbock, MD (Medicine)
Toll receptors; pathophysiology of sepsis and pelvic inflammatory disease.
Heinrich Gottlinger, Ph.D., MD (Program in Molecular Medicine; Program in Gene Function and Expression)
Molecular Biology of HIV-1.
|Ellen M. Gravallese, MD (Medicine) |
Pathogenic mechanisms of inflammatory arthritis and the processes by which inflammation destroys cartilage and bone.
|Sharone Green, MD (Center for Infectious Disease and Vaccine Research)|
Immunity and pathogenesis of West Nile and dengue viruses.
Dale L. Greiner, Ph.D. (Medicine)
T cell development and regulation of autoimmune disorders.
John E. Harris, MD, .Ph.D., (Medicine, Division of Dermatology)
Understanding the pathogenesis of autoimmune vitiligo with a focus on developing new treatments.
|Eric Huseby, Ph.D. (Pathology) |
Development of T cell tolerance of self and the autoimmune consequence of when it fails.
Joonsoo Kang, Ph.D.(Pathology)
Molecular and cellular mechanisms of T cell lineage commitment.
Michelle Kelliher, Ph.D. (Molecular Genetics and Microbiology)
Apoptosis and cancer.
|Richard Konz, Jr. (Medicine) |
Flow Cytometry and High-Speed Cell Sorting.
Hardy Kornfeld, MD (Medicine)
Host defense against respiratory pathogens.
Timothy F. Kowalik , Ph.D. (Microbiology & Physiological Systems)
Cell activation and DNA viruses.
|Evelyn Kurt-Jones, Ph.D. (Medicine)|
Signaling by receptors on monocytes and macrophages that mediate the innate immune response to bacterial and viral infection.
|Eicke Latz, MD, Ph.D. (Medicine, Infectious Disease)|
Study of Mechanisms of Toll-like receptor and inflammasome activation and their role for sterile inflammatory diseases.
|Edward Leiter, Ph.D. (Jackson Laboratory) |
Genetics and Pathogenesis of Diabetes and Inflammatory Bowel Disease in Mice
|Stuart M. Levitz, MD (Infectious Disease)|
Host defenses against fungal infections, model vaccines exploiting mannosylation.
|Dan Libraty, MD (Infectious Disease)|
Studies of human cellular immune responses contributing to pathogenesis and/or protective immunityinemerging viral diseases.
|Egil Lien, Ph.D. (Medicine) |
Pathogen recognition and evasion of innate immune signaling. Toll-like receptors.
|Craig Lilly, MD (Medicine)|
Mechanisms of airway inflammation, biomarkers of disease and critical care outcomes.
|Vladimir Litvak, Ph.D. (Microbiology & Physiological Systems) |
Systems biology approaches to study the regulation of innate immune responses and anti-viral immunity
Shan Lu, MD, Ph.D. (Medicine)
Immunogenicity of protein and peptide antigens. Structure and function relationship of envelope proteins of the immunodeficiency viruses. Roles of cytokines and adjuvants in DNA immunization.
|Jeremy Luban, MD (Program in Molecular Medicine)|
HIV-1 replication, pathogenesis, and immunity
Elizabeth J. Luna, Ph.D. (Cell Biology)
Membrane skeletons in motile cells.
Katherine F. Ruiz de Luzuriaga, MD (Pediatrics)
Virology and immunology of early vertical HIV-1 infection andHIV-1 specific cytotoxic T cells in vertical infection.
|Pranoti Mandrekar, Ph.D. (Medicine)|
Signaling pathways in liver inflammation.
Anuja Mathew Ph.D. (Medicine)
Immune Responses to Dengue Virus Infections
|Ann Moormann, Ph.D., MPH (Pediatrics, Quantitative Health)|
Viral Immunology and Epidemiology
|John P. Mordes, MD (Medicine) |
We study the immunogenetics of autoimmune diabetes in rats and the human genome.
Kenan C. Murphy, Ph.D. (Microbiology and Physiological Systems)
Recombinogenetic engineering technologies for pathogenic bacteria
|Peter Newburger, MD (Pediatrics, Cancer Biology)|
Neutrophil function and gene expression.
|Javier Gordon Ogembo, Ph.D. (Medicine)|
Manipulation of virus entry and replication mechanisms for the development of prophylactic and therapeutic vaccines.
|Sanjay Ram, MD (Medicine, Division of Infectious Diseases)|
Complement evasion strategies of microbes, with an emphasis on Neisseria meningitides and N. gonorrhoeae.
|Peter Rice, MD (Infectious Diseases and Immunology) |
Host Interactions with Neisseriagonorrhoeae
Kenneth L. Rock, MD (Pathology)
Mechanisms to control display of foreign antigens to immune system.
|Ann Rothstein, Ph.D. (Medicine, Rheumatology)|
Innate immune triggers of systemic autoimmune diseases.
|Christopher Sassetti, Ph.D. (Microbiology and Physiological Systems)|
Molecular mechanisms underlying tuberculosis pathogenesis.
|Celia A. Schiffer, Ph.D. (Biochemistry & Molecular Pharmacology)|
Elucidating alterations in molecular recognition that allows drug resistance to HIV-1 and Hepatitis C virus
Madelyn Schmidt, Ph.D. (Microbiology & Physiological Systems)
Gene therapy approaches to treat genetic immunodeficiencies.
|Carol Schrader, Ph.D. (Microbiology & Physiological Systems) |
B cell immunology.
Liisa K. Selin, MD (Pathology)
Mechanisms of viral immunology.
|David V Serreze BS, MS, Ph.D. (Medicine: Jackson Laboratory)|
Genetic control mechanisms of immune tolerance and diabetes
|Leonard Shultz, PhD (Medicine: Jackson Laboratories) |
Mouse Models for Human Immunological Diseases and Hematolymphoid Cell Engraftment.
Neal S. Silverman, Ph.D. (Medicine)
Immune signaling pathways.
Merav Socolovsky, Ph.D., MBBS (Cancer Biology)
Molecular mechanisms regulating the homeostasis of hematopoietic progenitors.
Janet M. Stavnezer, Ph.D. (Microbiology & Physiological Systems)
Molecular genetics of the Immunoglobulin Heavy Chain Switch
|Susan Swain, Ph.D. (Pathology)|
Regulation of CD4 memory generation and strategies to compensate for defects that arise with Aging.
Gyongyi Szabo, MD, Ph.D. (Medicine)
Cellular and molecular mechanisms of ethanol-induced monocyte aberrations in normals and immunosuppressed trauma patients; selective inhibition of antigen-specific T lymphocyte proliferation by acute ethanol exposure.
Eva Szomolanyi-Tsuda, MD (Pathology)
Interactions of viral gene products and host immune systems.
Masanori Terajima, MD, Ph.D.(Medicine)
|Michael R. Volkert, Ph.D. (Microbiology and Physiological Systems)|
Oxidative stress resistance genes.
|Jennifer Wang, MD (Medicine, Infectious Disease)|
Raymond M. Welsh, Ph.D.(Pathology; Microbiology and Physiological Systems)
Viral and tumor immunology.
Bruce A. Woda, MD (Pathology)
Transmembrane interactions of lymphocyte receptors with cytoskeletal elements; autoimmune diabetes.
Robert T. Woodland, Ph.D. (Microbiology & Physiological Systems)
Regulation of the immune response.
Maria Zapp, Ph.D. (Molecular Medicine)
Molecular mechanisms of mRNA export; functional gene transfer into human fetal hematopoietic stem cells.
For those UMMS faculty interested in becoming an Immunology and Microbiology Program Committee member,
please forward your full CV to Lawrence.Stern@umassmed.edu .