Faculty Research
Program Directors
Trudy G. Morrison , PhD (Molecular Genetics & Microbiology)
Glycoprotein processing and assembly; mechanisms of paramyxovirus membrane fusion.
Rachel M. Gerstein , PhD (Molecular Genetics & Microbiology)
Developmental regulation of V(D)J recombination and B cell development.
Committee Chair
Leslie J. Berg , PhD (Pathology)
Signal transduction proteins involved in T-cell development and activation.
Committee Members
Elliot J. Androphy , MD (Medicine)
Pathogenesis of papillomavirus infections.
Rita Bortell , PhD (Medicine, Diabetes)
Pathogenesis of autoimmune diabetes.
Irene Bosch , PhD (Medicine)
Understanding the cellular response to viral infection
Francis Ka-Ming Chan , PhD (Pathology)
Analysis of TNF receptor signaling in healthy and diseased immune systems.
Jason J. Chen , PhD (Medicine)
Cell cycle checkpoints and apoptosis of cells expressing papillomavirus oncogenes.
Paul R. Clapham , PhD (Molecular Medicine)
HIV receptors and cellular tropisms.
Ronald C. Desrosiers , PhD (Molecular Genetics & Microbiology)
Molecular mechanisms of HIV.
Francis A. Ennis , MD (Medicine)
Clinical and laboratory studies on the immune response of host to virus infections,
emphasizing the role of cellular responses in virus infections.
Robert W. Finberg , MD (Medicine)
Host cell surface proteins and viruses; Cellular activation mediated by cell surface proteins.
Kate Fitzgerald , PhD (Medicine)
Anti-viral innate immune signaling.
Uri Galili, MD (Medicine)
Ricardo Gazzinelli, D.Sc., D.V.M (Infectious Diseases and Immunology Medicine)
Jon D. Goguen , PhD (Molecular Genetics & Microbiology)
Function and regulation of virulence determinants in Yersinia pestis.
Douglas T. Golenbock , MD (Medicine)
Toll receptors; pathophysiology of sepsis and pelvic inflammatory disease.
Heinrich Gottlinger , PhD, MD (Program in Molecular Medicine; Program in Gene Function
and Expression)
Molecular Biology of HIV-1.
Dale L. Greiner , PhD (Medicine)
T cell development and regulation of autoimmune disorders.
Steven R. Grossman , MD, PhD (Cancer Biology)
The ubiquitin/proteasome system and cancer.
Eric Huseby, PhD (Pathology)
Development of T cell tolerance of self and the autoimmune consequence of when it fails.
Ronald M. Iorio , PhD (Molecular Genetics & Microbiology)
Mechanism of neutralization of animal viruses; viral glycoprotein structure and function.
Joonsoo Kang , PhD (Pathology)
Molecular and cellular mechanisms of T cell lineage commitment.
Michelle Kelliher , PhD (Molecular Genetics & Microbiology)
Apoptosis and cancer.
Richard Konz, Jr. (Medicine)
Flow Cytometry and High-Speed Cell Sorting.
Hardy Kornfeld , MD (Medicine)
Host defense against respiratory pathogens.
Timothy F. Kowalik , PhD (Molecular Genetics & Microbiology)
Cell activation and DNA viruses.
Evelyn Kurt-Jones , PhD (Medicine)
Signaling by receptors on monocytes and macrophages that mediate the innate immune
response to bacterial and viral infection.
Edward Leiter, Ph.D. (Jackson Laboratory)
Genetics and Pathogenesis of Diabetes and Inflammatory Bowel Disease in Mice
John M. Leong , MD, PhD (Molecular Genetics & Microbiology)
Interactions of pathogenic bacteria with mammalian cells.
Stuart M. Levitz, MD (Infectious Diseases)
Host defenses against fungal infections, model vaccines exploiting mannosylation.
Dan Libraty, MD (Infectious Diseases)
Studies of human cellular immune responses contributing to pathogenesis and/or
protective immunity in emerging viral diseases.
Egil Lien , PhD (Medicine)
Pathogen recognition and evasion of innate immune signaling.
Toll-like receptors.
Craig Lilly, MD (Medicine)
Shan Lu , MD, PhD (Medicine)
Immunogenicity of protein and peptide antigens. Structure and function relationship of
envelope proteins of the immunodeficiency viruses. Roles of cytokines and adjuvants
in DNA immunization.
Elizabeth J. Luna , PhD (Cell Biology)
Membrane skeletons in motile cells.
Katherine F Ruiz de Luzuriaga , MD (Pediatrics)
Virology and immunology of early vertical HIV-1 infection and HIV-1 specific
cytotoxic T cells in vertical infection.
William Marshall, MD (Infectious Diseases and Immunology)
Mechanisms that viruses employ to evade innate immunity, including cell-mediated
death pathways that ordinarily regulate viral replication.
Peter Rice, MD (Infectious Diseases and Immunology)
Host Interactions with Neisseria gonorrhoeae
Kenneth L. Rock , MD (Pathology)
Mechanisms to control display of foreign antigens to immune system.
Aldo A. Rossini , MD (Medicine)
Immunological aspects of animal models of diabetes mellitus.
Alan L. Rothman , MD (Medicine)
Immunopathogenesis of viral infections; T lymphocyte responses.
Madelyn Schmidt , PhD (Molecular Genetics & Microbiology)
Gene therapy approaches to treat genetic immunodeficiencies.
Carol Schrader , PhD (Molecular Genetics & Microbiology)
Liisa K. Selin , MD (Pathology)
Mechanisms of viral immunology.
Leonard Shultz, Ph.D. (Jackson Laboratories)
Mouse Models for Human Immunological Diseases and Hematolymphoid Cell
Engraftment.
Neal S. Silverman , PhD (Medicine)
Immune signaling pathways.
Merav Socolovsky , PhD, MBBS (Cancer Biology)
Molecular mechanisms regulating the homeostasis of hematopoietic progenitors.
Janet M. Stavnezer , PhD (Molecular Genetics & Microbiology)
Molecular genetics of the Immunoglobulin Heavy Chain Switch
Lawrence J. Stern , Ph.D. (Pathology)
Molecular recognition in the immune system.
Mario Stevenson , PhD (Molecular Medicine, Molecular Genetics & Microbiology)
Regulation of HIV-1 infectivity and pathogenesis of AIDS.
John L. Sullivan , MD (Pediatrics, Pathology, Molecular Genetics & Microbiology)
Immunodeficiency syndromes and antiviral host defense mechanisms.
Gyongyi Szabo , MD, PhD (Medicine)
Cellular and molecular mechanisms of ethanol-induced monocyte aberrations in normals and
immunosuppressed trauma patients; selective inhibition of antigen-specific T lymphocyte
proliferation by acute ethanol exposure.
Eva Szomolanyi-Tsuda , MD (Pathology)
Interactions of viral gene products and host immune systems.
Masanori Terajima , MD, PhD (Medicine)
Immunopathogenesis of hantavirus infections, hantavirus pulmonary syndrome (HPS)
and hemorrhagic fever renal syndrome (HFRS). Host immune reaction against
vaccinia virus.
Raymond M. Welsh , PhD (Pathology and Molecular Genetics & Microbiology)
Viral and tumor immunology.
Bruce A. Woda , MD (Pathology)
Transmembrane interactions of lymphocyte receptors with cytoskeletal elements;
autoimmune diabetes.
Robert T. Woodland , PhD (Molecular Genetics & Microbiology)
Regulation of the immune response.
Maria Zapp , PhD (Molecular Medicine)
Molecular mechanisms of mRNA export; functional gene transfer into human fetal
hematopoietic stem cells.