Lazare Research Building at Univeristy Campus

Research @ UMMS

Loss of the Alox5 gene impairs leukemia stem cells and prevents chronic myeloid leukemia
Paper | Research Program

Phosphorylation-Driven Assembly of the RIP1-RIP3 Complex Regulates Programmed Necrosis and Virus-Induced Inflammation
Paper | Research Program

A Tyramine-Gated Chloride Channel Coordinates Distinct Motor Programs of a Caenorhabditis elegans Escape Response
Paper | Research Program

Orally delivered siRNA targeting macrophage Map4k4 suppresses systemic inflammation
Paper | Research Program

A PP2A regulatory subunit regulates C. elegans insulin/IGF-1 signaling by modulating AKT-1 phosphorylation
Paper | Research Program

More Research

Division of Infectious Diseases and Immunology

Research Programs

  • Treatment of HIV-infected Persons
  • Viral Immunology
  • DNA Vaccines
  • Antibacterial Host Defenses
  • Intracellular Signalling
  • Antiviral effects of Nitric Oxide
  • Cellular Growth Regulation
  • Innate immune recognition and signalling in humans and insects

Recent Publications

Antiviral responses: different roles for different tolls. Finberg RW, Wang JP. Immunity. 2009 Feb;30(2):173-5. PMID: 19239899

ROLE OF P38 AND EGR-1 IN THE MACROPHAGE RESPONSE TO GROUP B STREPTOCOCCUS. Kenzel S, Santos-Sierra S, Deshmukh SD, Moeller I, Ergin B, Fitzgerald KA, Lien E, Akira S, Golenbock DT, Henneke P. Infect Immun. 2009 Mar 30. [Epub ahead of print] PMID: 19332535

Regulation of chemokine receptor by Toll-like receptor 2 is critical to neutrophil migration and resistance to polymicrobial sepsis. Alves-Filho JC, Freitas A, Souto FO, Spiller F, Paula-Neto H, Silva JS, Gazzinelli RT, Teixeira MM, Ferreira SH, Cunha FQ. Proc Natl Acad Sci U S A. 2009 Mar 10;106(10):4018-23. Epub 2009 Feb 20. PMID: 19234125

Impact of Toll-like Receptor 4 on the Severity of Acute Pancreatitis and Pancreatitis-Associated Lung Injury in Mice. Sharif R, Dawra RK, Wasiluk K, Phillips P, Dudeja V, Kurt-Jones E, Finberg R, Saluja AK. Gut. 2009 Feb 6. [Epub ahead of print] PMID: 19201771

Distinct Patterns of Dendritic Cell Cytokine Release Stimulated by Fungal {beta}-Glucans and Toll-Like Receptor Agonists. Huang H, Ostroff GR, Lee CK, Wang JP, Specht CA, Levitz SM. Infect Immun. 2009 Mar 9. [Epub ahead of print] PMID: 19273561

Increased activity of indoleamine 2,3-dioxygenase in serum from acutely infected dengue patients linked to gamma interferon antiviral function. Becerra A, Warke RV, Xhaja K, Evans B, Evans J, Martin K, de Bosch N, Rothman AL, Bosch I. J Gen Virol. 2009 Apr;90(Pt 4):810-7. Epub 2009 Mar 4. PMID: 19264674

University of Massachusetts Medical School

55 Lake Avenue North
Worcester, MA 01655 
508-856-1720

UMass Memorial Medical Center

Memorial Campus
119 Belmont Street
Worcester, MA 01605
508-334-5412