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Michael Brodsky, Ph.D.
Academic Role: Assistant Professor
Faculty Appointment(s) In:
Program in Gene Function and Expression
Program in Molecular Medicine
Other Affiliation(s):
Interdisciplinary Graduate Program
Representative Publications
Noyes, M.B., Christensen, R.G., Wakabayashi, A., Stormo, G.D., Brodsky, M.H., Wolfe, S.A. (2008) Analysis of homeodomain specificities allows the family-wide prediction of preferred recognition sites. Cell 133, 1277-1289.
Oikemus, S.R., Queiroz-Machado, J., Lai, K., McGinnis, N., Sunkel, C., Brodsky, M.H. (2006). Epigenetic telomere protection by Drosophila DNA damage response pathways. PLoS Genet. 2, e71.
Meng, X., Brodsky, M.H., Wolfe S.A. (2005). A bacterial one-hybrid system for determining the DNA-binding specificity of transcription factors. Nat Biotechnol. 23, 988-994.
Oikemus, S.R., McGinnis, N., Queiroz-Machado, J., Tukachinsky, H., Takada, S., Sunkel, C.E., Brodsky, M.H. (2004). Drosophila atm/telomere fusion is required for telomeric localization of HP1 and telomere position effect. Genes Dev. 15, 1850-1861.
Brodsky, M.H., Weinert, B., Tsang, G., Rong, Y.S., McGinnis, N.M., Golic, K.G., Rio, D., Rubin, G.M. (2004). Drosophila Chk2 and p53 regulate multiple DNA repair and apoptotic pathways following DNA damage. Mol. Cell. Biol. 24, 1219-1231.
Abdu, U., Brodsky, M.H., Schupbach, T. (2002). Activation of a meiotic checkpoing during Drosophila oogenesis regulates the translation of Gurken through Chk2/Mnk. Curr. Biol. 12, 1-20.
Rong, Y.S., Titen, S., Xie, H., Golic, M.M., Bastiani, M., Bandyopadhyay, P., Olivera, B.M., Brodsky, M.H., Rubin, G.M., Golic, K.G. (2002). Targeted mutagenesis by homologous recombination in Drosophila melanogaster. Genes Dev. 16, 1568-1581.
Brodsky, M.H., Nordstrom, W., Tsang, G., Kwan, E., Rubin, G.M., Abrams, J.M. (2000). Drosophila p53 binds a damage response element at the reaper locus. Cell 101, 103-113.
Sekelsky, J.J., Brodsky, M.H., Burtis, K.C. (2000). DNA Repair in Drosophila. Insights from the Drosophila genome sequence. J. Cell. Biol. 150, F31-F36.
Brodsky, M.H., Sekelesky, J.J., Tsang, G., Hawley, R.S., Rubin, G.M. (2000). mus304 encodes a novel checkpoint protein required during Drosophila development. Genes Dev. 14, 666-678.
Office: 623
Phone: 508-856-1640
E-mail: Michael.Brodsky@umassmed.edu
Keywords:
Oncogenes/tumor suppressors,
Chromosome Structure & Dynamics,
Apoptosis,
DNA Damage and Repair,
Organisms - Drosophila
Postdoctoral Position Available
A postdoctoral position is available to study in this laboratory.
Contact Dr. Brodsky for additional details.
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