Section: Publications

Postdoctoral Position Available

Schahram Akbarian, Ph.D.,M.D.

Academic Role: Associate Professor

Faculty Appointment(s) In:
   Psychiatry

Other Affiliation(s):
   Brudnick Neuropsychiatric Research Institute
   Interdisciplinary Graduate Program
   Program in Neuroscience

 

Representative Publications

Schroeder FA, Pental KL, Matevossian A., Jones SR, Konradi C, Tapper AR, Akbarian S (2008) Drug-induced activation of dopamine D₁ receptor signaling and inhibition of class I/II histone deacetylase induces chromatin remodeling in reward circuitry and modulates cocaine-related behaviors. Neuropsychopharmacology 33:2981-2992.

Jiang Y, Matevossian A, Huang HS, Straubhaar J, Akbarian S (2008) Isolation of neuronal chromatin from brain tissue. BMC Neuroscience 9:42.

Mellios N, Huang HS, Grigorenko A, Rogaev E, Akbarian S (2008) A set of differentially expressed miRNAs, including miR-30a-5p, act as post-transcriptional inhibitors of BDNF in prefrontal cortex. Human Molecular Genetics 17: 3030-3042.

Jiang Y., Langley B., Lubin F.D., Renthal W., Wood M.A., Yasui D.H., Kumar A., Nestler E.J., Akbarian S., Beckel-Mitchener A.C. (2008) Epigenetics in the nervous system. Journal of Neuroscience 28: 11753-11759.

Mellios  N, Huang HS, Galdzicka M, Ginns E, Akbarian S (2009) Molecular determinants of dysregulated GABAergic gene expression in schizophrenia. Biological Psychiatry 65: 1006-1014.

Akbarian S (2008) Restoring neuronal synchrony in schizophrenia. American  J Psychiatry 165:1507-1509.

Matevossian A., Akbarian S. (2008) A chromatin assay for human brain tissue. Journal of Visualized Experiments 13: pii: 7171. doi: 10.3791/717.

Connor, CM, Akbarian S (2008) DNA methylation changes in schizophrenia and bipolar disorder. Epigenetics 3(2): 55-58.

Akbarian S (2008) Approaching the molecular pathology of suicide. Biological Psychiatry 64: 643-644.

Akbarian S, Huang HS (2008) Epigenetic regulation in human brain – focus on histone lysine methylation. Biological Psychiatry 65: 198-203.

Matevossian A., Akbarian S. (2008) Neuronal nuclei isolation from human postmortem brain tissue. Journal of Visualized Experiments 20: pii:914. Doi:10.3791/914.

Connor CM, Guo Y, Akbarian S (2009) Cingulate white matter neurons in bipolar disorder and schizophrenia. Biological Psychiatry 2009 Sep 1;66(5):486-93. Epub 2009 Jun 25.

Febo M, Akbarian S, Schroeder FA, Ferris CF. (2009) Cocaine-induced metabolic activation in cortico-limbic circuitry is increased after exposure to the histone deacetylase inhibitor, sodium butyrate. Neurosci Lett. 465:267-271.

Akbarian S (2009) The molecular pathology of schizophrenia-Focus on histone and DNA modifications. Brain Res Bull [Epub ahead of print].

Phone: 508-856-2674
E-mail: Schahram.Akbarian@umassmed.edu
Keywords: Genetic Systems, Neurobiology

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Postdoctoral Position Available A postdoctoral position is available to study in this laboratory. Contact Dr. Akbarian for additional details.