People with diabetes are vulnerable to a variety of complications over time. Health-care providers all agree that strict control of blood sugar makes complications less likely. This was shown clearly by the Diabetes Control and Complications Trial. Control of blood sugar is the best way to minimize the risk of complications.
Even the very best control may not be able to eliminate all complications, and the risk of increases with the length of time you have diabetes. Diabetes complications affect the eyes, kidneys, nerves, and large and small blood vessels. Here is a list.
|Coronary artery disease
Peripheral vascular disease
Large blood vessels
Small blood vessels
Blood vessels of legs and feet
Diabetes can affect the lens, which focuses light reflected from objects, the vitreous, a clear jelly-like substance through which light passes from the lens to the retina, and the retina, where images are formed and translated into electric impulses for interpretation by the brain.
Diabetic Retinopathy is a deterioration of the small blood vessels that nourish the retina. Although diabetic retinopathy is a serious cause of blindness, only a small percentage of persons with diabetic retinopathy lose their sight. There are two forms of diabetic retinopathy:
When massive bleeding into the vitreous has occurred, a vitrectomy may be performed. In this surgical procedure, the bloody vitreous is removed and replaced with clear, sterile fluids, restoring vision.
Cataracts are clouding of the normally clear lens. A cataract develops over years and causes blurred vision when a large part of the lens becomes cloudy. Causes of cataracts include aging, eye injuries, disease, heredity, and birth defects. Senile cataracts are a common eye problem among the elderly. Poor diabetes control can hasten the formation of senile cataracts. Metabolic cataracts are sometimes found in younger people with diabetes. Both types are treated by surgical removal of the lens. Eyeglasses, contact lenses, or intraocular lens implants restore vision following surgery.
To minimize the risk of cataracts, see your ophthalmologist for a complete eye exam at least once a year.
The kidneys filter waste products from the blood, rid the body of excess water, and eliminate certain chemicals. Needed chemicals, proteins, and red and white blood cells remain in the blood stream. The kidneys produce about a quart of urine every day to maintain the body's fluid balance.
Diabetic nephropathy is a complication of long-term diabetes that results in damage to the bundles of capillaries that form the kidneys' filtering system. Diabetic nephropathy develops in stages over many years. Kidney filtering becomes less efficient, and certain proteins leak out. Protein in the urine may be the first sign of nephropathy. Other signs include high blood pressure, weight gain from fluid retention, fatigue, and just feeling ill. Kidney function tests help determine the degree of kidney damage. Treatments for kidney failure include hemodialysis (done at the hospital 3 times a week), peritoneal dialysis (done 3 to 4 times a day at home), and kidney transplants.
Diabetic bladder dysfunction occurs when damage to the nerves of the bladder results in incomplete emptying of the bladder. Urine that remains in the bladder is stagnant, and bacteria grow in it. The bacteria travel up to the kidney and cause infection. Surgery may be required, but sometimes medication helps.
Urinary tract infections may develop in persons with uncontrolled diabetes. Symptoms include excessive urination, a burning sensation with urination, and low back pain. If untreated, the infection travels up the ureters to the kidney, possibly causing permanent damage. Women are more likely to develop urinary tract infections. Prompt treatment with antibiotics prescribed by your doctor is essential. Remember to take the pills for the period prescribed, even if your symptoms go away.
Nearly 70% of persons with diabetes experience some degree of nerve damage or neuropathy. Neuropathy occurs in people with Type I and Type II diabetes, due to metabolic changes associated with diabetes. Constant high blood sugar destroys both nerve fiber (axon) and the fatty insulation that surrounds it (myelin ). Damaged nerves do not transmit proper signals, resulting in a loss of sensation, hypersensation, or pain.
Peripheral neuropathy is the most common form. Varying from mild to severe, it causes changes in sensation that begin in the toes move up to the feet and legs. One may experience numbness, tingling, burning, dull ache, or stabbing pain and cramping, which is worse at night. The skin can become so sensitive that pressure from clothes is painful. Severe neuropathy may cause weakness and unbalanced walking. The greatest danger is foot ulcers, which result when lack of sensation causes people to continuing walking on injured feet.
Many treatments are available for peripheral neuropathy, including medications and topical creams. Not all are effective for everyone. Better diabetic control helps some patients. A painful neuropathy may change to a numb feeling after a while. And neuropathies sometimes disappear on their own.
Autonomic neuropathy involves the nerve supply to small blood vessels and sweat glands of the skin, the stomach, the bowls, the bladder, the heart, and the nervous system. It is most often associated with long-term diabetes, poor control, and elevated blood sugar. Symptoms vary, depending on the affected area, and may include:
Various medications may be prescribed to control nausea, vomiting, diarrhea, sudden drops in blood pressure, and recurrent urinary tract infections. Penile implants and vacuum systems are useful in treating impotence.
If you experience symptoms of any form of macrovascular disease, go to a hospital emergency room at once.
Ulcers of the legs and feet occur in people with diabetes due to the combination neuropathy and peripheral vascular disease. Neuropathy causes a loss of sensation, so that foot injuries may go untreated and become infected. Decreased circulation to the feet and legs slows healing. Proper nourishment does not reach damaged tissue, and infected material is not destroyed. Even a small injury may progress to an ulcer. To prevent foot problems, follow the foot care instructions in Chapter 11.
An increase in cavities and infectious periodontal disease has been found in people with poor diabetes control. To prevent tooth decay, brush your teeth after every meal, floss daily, and see your dentist every six months. Mouthwashes, baking soda, and hydrogen peroxide may provide additional protection against bacteria growth.
REMEMBER: The care of diabetes is a team effort involving you, your physician, and the diabetes education staff where you receive your medical care. This handbook cannot-and was not meant to-replace this team effort.
This handbook embodies the approach of the diabetes care team at the University of Massachusetts Medical School. Different diabetes care teams may approach some aspects of diabetes care in ways that differ from those in this handbook. While most teams are in close agreement regarding the GENERAL PRINCIPLES of diabetes care, they may differ in the DETAILS. There can be more that one "right" way to approach a specific issue in diabetes management.
Always remain in touch with your diabetes care team, and bring any questions you may have about the materials in this handbook to their attention!
Copyright 1995-1999 Ruth E. Lundstrom, R.N. and Aldo A. Rossini, M.D. All rights reserved.
Feedback: send e-mail to Dr. Aldo Rossini