Interdisciplinary Graduate Program Courses

The courses listed below inlcude required courses of the core curriculum, research and milestone courses, as well as program specific advanced topics, seminars, journal clubs and tutorials for specialization in Interdisciplinary studies.

  • Professionalism and Research Conduct (PARC) | BBS 601

    Programs: Biochemistry & Molecular Pharmacology, Bioinformatics & Computational Biology, Cancer Biology, Cell Biology, Immunology & Microbiology, Interdisciplinary, MD/PhD, Neuroscience, Translational Science

    This is a required course for all 3rd year Basic Sciences students and all MD/PhD students entering doctoral study but who are not on the CPHR track. The PARC course helps to center our students in areas that are foundational to success in research - responsible data management, management of intellectual property, the ethical use of research subjects, recognizing and resolving conflicts of interest, professionalism in peer review and publishing, engaging mentors and career exploration and planning. The PARC course comprises faculty-led presentations and small group discussions with case studies and workshop material. An on line learning module (CITI training program comprising many case studies) is also included which must be completed before the end of the fall semester. Students required to take the fall PARC course will be block-registered.

    Coordinator: Anthony Carruthers

    Semester Offered: Fall 

    Last Taught: Fall 2016

  • Communicating Science | BBS 602

    Programs: Biochemistry & Molecular Pharmacology, Bioinformatics & Computational Biology, Cancer Biology, Cell Biology, Immunology & Microbiology, Interdisciplinary, Neuroscience, Translational Science

    This course seeks to help prospective scientists in the biological and medical sciences communicate their work effectively, in writing, graphics, and oral presentations. The course teaches how to prepare a research paper using words, statistics, and figures; how to present science to a lay audience; how to write a grant proposal; and how to present orally to scientific peers.

    Coordinator: Philip Zamore

    Semester Offered: Fall

    Last Taught: Taught every fall

  • Foundations in Biomedical Science | BBS 614

    Programs: Biochemistry & Molecular Pharmacology, Bioinformatics & Computational Biology, Cancer Biology, Cell Biology, Immunology & Microbiology, Interdisciplinary, Neuroscience, Pathway to Graduate Study, Translational Science

    This problem-based course provides learning opportunities through exploration of multidisciplinary areas of contemporary biomedical research, and creates a forum for practice in the skills required for research.

    Coordinator: Mary Ellen Lane

    Semester Offered: Fall

    Last Taught: Fall 2016

  • Using Animals in Biomedical Research | BBS 701

    Programs: Biochemistry & Molecular Pharmacology, Bioinformatics & Computational Biology, Cancer Biology, Cell Biology, Immunology & Microbiology, Interdisciplinary, Translational Science

    It is to the benefit of both science and animals to have a formal understanding of animal needs and animal use in the research environment. The goal of this course is to provide a sufficient appreciation of laboratory animal biology, care, and use to engender better science and enhanced animal welfare. Topics include controversies surrounding animal use in research; choosing an animal model; the Institutional Animal Care and Use Committee; normative biology of rodent and non-rodent laboratory animals; diseases and other stressors and their effects on research; humane experimental endpoints and pain and its alleviation. There are also two laboratory sessions.

    Coordinator: Jerald Silverman

    Semester Offered: Fall

    Last Taught: Fall 2016

  • Cancer Biology | BBS 725

    Programs: Cancer Biology, Cell Biology, Interdisciplinary

    This course will provide students with a rigorous and comprehensive understanding of the mechanisms that will underlie the genesis and progression of human cancers. It will build on the basic science knowledge acquired in the core curriculum and appreciation of the cancer as a disease obtained from Tumor Pathology course. The salient topics to be covered include stem cells, oncogenes, and tumor suppressor genes, tumor-host interactions, invasion, metasisis, and angiogenesis. A major theme of the course will be to integrate the biology of cancer with the clinical behavior of tumors.

    Course Coordinator: Arthur Mercurio

    Semester Offered: Fall

    Last Taught: Fall 2015

  • Principles of Light and Electron Microscopy | BBS 732

    Programs: Cell Biology, Interdisciplinary

    Principles and application of microscopy in biomedical research for graduate students at all levels. Demonstrations and laboratory exercises will be incorporated into some of the blocks of the instruction. This course is designed to teach the biologist how microscopes work and how to optimize image quality.

    Course Coordinator: Michael Sanderson

    Semester Offered: Spring, odd years

    Last Taught: Spring 2015

  • Cytoskeleton & Disease | BBS 733

    Programs: Cell Biology, Interdisciplinary

    This course studies the functions of actin- and microtubule-based cytoskeleton systems in the context of human disease and will be organized as a series of seminars with presentations by students and faculty. Discussions will include how molecular information contributes to diagnosis and treatment of disease and how clinical phenotypes elucidate protein functioning in whole organisms.

    Course Coordinator: Elizabeth Luna

    Semester Offered: Fall, odd years

    Last Taught: Has not been taught within last two years

  • Human Genetics | BBS 736

    Programs: Biochemistry & Molecular Pharmacology, Bioinformatics & Computational Biology, Cancer Biology, Cell Biology, Immunology & Microbiology, Interdisciplinary, Translational Science

    This course focuses on the human genetic knowledge and concepts which underlies almost every aspect of human health, both in normal function and disease. We will cover chromosomal, single gene, and multifactorial disorders, including quantitative analysis of Mendelian and non-Mendelian inheritance, human cancer genetics, and recent developments in human genome research. Problem solving will involve clinical, molecular and statistical data. We hope to provide a framework for understanding a fast growing and highly technical field, and an appreciation of how current research impacts many aspects of medicine as well as biomedical research. This course follows the Medical School calendar - check with Course Coordinator regarding class schedule.

    Course Coordinator: John Landers

    Semester Offered: Fall

    Last Taught: Fall 2015

  • Eukaryotic Gene Expression | BBS 738

    Programs: Cell Biology, Interdisciplinary

    This course encompasses current topics in eukaryotic gene regulation including the study and discussion of current research articles. Course goals are to improve skills in reading, presenting, discussing and critically analyzing research articles and to obtain an up-to-date understanding of some key topics in eukaryotic gene regulation.

    Program Coordinator: Michael Green

    Semester Offered: Spring, even years

    Last Taught: Has not been taught within past two years

  • Developmental Biology | BBS 739

    Programs: Cell Biology, Interdisciplinary

    This course will provide basic instruction in contemporary Developmental Biology with an emphasis on animal development.  The course will familiarize students with development in each of the major model systems (worms, flies, frogs, fish, chick, mouse) and expose them to commonly used techniques (genetics, molecular biology, cell biology, biochemistry) in the context of animal development. Each topic will be introduced by a lecture and subsequently explored in depth by discussion of relevant articles from the literature.  Each student will be expected to lead at least one group discussion.

    Coordinator: Michael Brodsky

    Semester Offered: Fall

    Last Taught: Has not been taught with past two years

  • Introduction to cellular metabolism and disease | BBS 748

    Programs: Interdisciplinary, Pathway to Graduate Study, Translational Science

    This intense 3-week course will expose students to a variety of topics related to cellular metabolism. The course will cover material ranging from foundational principles to current leading-edge research. The principles and mechanisms regulating metabolism will be explored from multiple perspectives – biochemistry, biophysics, genetics, molecular biology and cell biology.

    Course Coordinator: Brian Lewis

    Semester Offered: Fall

    Last Taught: Fall 2016

  • Molecular Biology of Cell Cycle | BBS 761

    Programs: Interdisciplinary

    This course covers genetic, biochemical and cellular mechanisms of cell cycle control. Topics include genetic screens for cell cycle regulators, cell cycle checkpoints, cell cycle regulation of DNA replication and chromosome structure, and the cell cycle in development and cancer.

    Course Coordinator: Nicholas Rhind

    Semester Offered: Spring, odd years

    Last Taught: Spring 2015

  • Genetic Systems | BBS 762

    Programs: Interdisciplinary

    This course will focus on critical analysis of genetic model systems for the study of numerous biological processes. The course will consist primarily of critical reading and discussion of research articles.  Drosophila and C.elegans genetics will be a major thrust of the course, but other eukaryotic genetic systems will also be included.  A final project will consist of a written and oral scientific proposal.

    Coordinator: Michael Brodsky

    Semester Offered: Fall

    Last Taught: Has not been taught within past two years

  • DNA Repair and Genome Stability | BBS 763

    Programs: Immunology & Microbiology, Interdisciplinary

    This lecture/paper discussion course focuses on mechanisms by which cells protect their genomes from endogenous and exogenous DNA damage using examples from the molecular to the cellular and from bacteria to humans. Lectures on a specific topic are followed by a discussion of recent papers from the literature. Lecturers are drawn from several departments to ensure a multidisciplinary approach.

    Course Coordinator: Michael Volkert

    Semester Offered: Fall, odd years

    Last Taught: Has not been taught within past two years

  • Stem Cell and Regenerative Biology | BBS 787

    Programs: Interdisciplinary

    Advanced course, lecture and discussion, recent information of stem cell biololgy, tissue regeneration, and potential therapeutics

    Course Coordinator: Yicktung (Tony) Ip

    Course Offered: Fall, odd years

    Last Taught: Has not been taught withing past two years

  • RNA Biology Journal Club | BBS 801

    Programs: Interdisciplinary

    A discussion of recent and classical papers covering various topics in RNA biology. Students will choose from a list of papers provided by course coordinators or from recent literature with approval from coordinators.

    Course Coordinator: Victor Ambros

    Semester Offered: Fall, Spring

    Last Taught: Fall 2016

  • Current Topics In Aging | BBS 803

    Programs: Interdisciplinary

    This is a journal club offered every two weeks to discuss papers on aging and genomic stablity. The topics will be mechanisms of aging; with a focus on genetics. The objectives are to cover a large number of papers that identify genes that act to promote or limit life span and theories of aging.

    Course Coordinator: Heidi Tissenbaum

    Semester Offered: Fall, Spring

    Last Taught: Fall 2014

  • Genome Biology Journal Club | BBS 804

    Programs: Interdisciplinary

    Papers published in high-profile journals relating to systems biology, genomics, chromosome structure and gene expression are discussed. Each participant is required to present one paper and to participate in other paper discussions.

    Course Coordinator: Marian Walhout

    Semester Offered: Spring

    Last Taught: Spring 2013

  • Student Research Seminar | BBS 812

    Programs: Interdisciplinary

    This course offers students an opportunity to learn scientific information and presentation skills. Students are required to attend the weekly IGP seminar series and to write a short critique on each seminar. The goal is for students to understand the important elements of a successful presentation including style, interaction and organization.

    Course Coordinator: Yicktung (Tony) Ip

    Semester Offered: Fall, Spring

    Last Taught: Fall 2014

  • Educational Outreach to High Schools and Middle Schools | BBS 843

    Programs: Interdisciplinary

    Middle and high school educational outreach coordinated through the IGP, Worcester Pipeline, and Regional Science Resource Center. IGP coordinated activities include development of in-class presentations and experiments in collaboration with high school teachers, and one-on-one and small group mentoring of high school science students. The Worcester Pipline Collaborative coordinates a range of programs with the Worcester Public Schools dedicated to educating and challenging minority and/or economically disadvantaged students for success in the health care and science professions. The Regional Science Resource Center at the Worcester Foundation Campus provides lab space, technical support, and materials for area teachers interested in implementing more inquiry-based, student-centered science in all classrooms. Course is not available to GSBS 1st year students. Students need to make an appointment with Dr. Theurkauf to discuss outreach opportunities prior to the start of semester.

    Course Coordinator: William Theurkauf

    Semester Offered: Fall, Spring

    Last Taught: Fall 2015

  • Tutorial in the Interdisciplinary Graduate Program | BBS 844

    Programs: Interdisciplinary

    Tutorial arranged with individual faculty.

    Course Coordinator: Craig Peterson

    Semester Offered: Fall, Spring

    Last Taught: Spring 2014

  • Laboratory Rotation | BBS 850

    Programs: Biochemistry & Molecular Pharmacology, Bioinformatics & Computational Biology, Cancer Biology, Cell Biology, Immunology & Microbiology, Interdisciplinary, Neuroscience, Translational Science

    Laboratory rotations are defined periods of research experience under the direction of a faculty member. They are intended to familiarize the student with concepts and techniques in several areas of research and to assist the student in evaluating research laboratories and projects that might be developed into a dissertation project. The student will participate in an ongoing research project, gain familiarity with concepts underlying the research, acquire a working knowledge of techniques used in the research, and write a report and present an oral summary of the results of the research.

    Course Coordinator: Faculty member in whose lab student is working

    Semester Offered: Fall, Spring

    Last Taught: Taught every Fall and Spring semester

  • Laboratory Rotation | BBS 851

    Programs: Biochemistry & Molecular Pharmacology, Bioinformatics & Computational Biology, Cancer Biology, Cell Biology, Immunology & Microbiology, Interdisciplinary, Neuroscience, Translational Science

    Laboratory rotations are defined periods of research experience under the direction of a faculty member. They are intended to familiarize the student with concepts and techniques in several areas of research and to assist the student in evaluating research laboratories and projects that might be developed into a dissertation project. The student will participate in an ongoing research project, gain familiarity with concepts underlying the research, acquire a working knowledge of techniques used in the research, and write a report and present an oral summary of the results of the research.

    Course Coordinator: Faculty member in whose lab student is working

    Semester Offered: Summer

    Last Taught: Taught every Summer

  • BBS Qualifying Exam | BBS 860

    Programs: Biochemistry & Molecular Pharmacology, Bioinformatics & Computational Biology, Cancer Biology, Cell Biology, Immunology & Microbiology, Interdisciplinary, Neuroscience, Translational Science

    Students are required to register for this course in the fall semester of the academic year in which they are to pass their Qualifying Examination.

    Course Coordinator: Mary Ellen Lane

    Semester Offered: Fall

    Last Taught: Taught every year 

  • BBS TRAC Meeting | BBS 865

    Programs: Biochemistry & Molecular Pharmacology, Bioinformatics & Computational Biology, Cancer Biology, Cell Biology, Immunology & Microbiology, Interdisciplinary, Neuroscience, Translational Science

    All Graduate Students are required to have at least one TRAC meeting each academic year. After passing their Qualifying Examination and selection of their TRAC, students are required to register for this course each fall semester until their Dissertation Advisory Committee is formed.

    Course Coordinator: Mary Ellen Lane

    Semester Offered: Fall

    Last Taught: Taught every year

  • Pre-Qualifying Research | BBS 870

    Programs: Biochemistry & Molecular Pharmacology, Bioinformatics & Computational Biology, Cancer Biology, Cell Biology, Immunology & Microbiology, Interdisciplinary, Neuroscience, Translational Science

    This course is for students who have selected a Program and Thesis Advisor but who have not yet passed their Qualifying Examination.

    Course Coordinator: Student's Thesis Advisor

    Semester Offered: Fall, Spring, Summer

    Last Taught: Taught every semester

  • Thesis Research | BBS 900

    Programs: Biochemistry & Molecular Pharmacology, Bioinformatics & Computational Biology, Cancer Biology, Cell Biology, Immunology & Microbiology, Interdisciplinary, Neuroscience, Translational Science

    Students register for Thesis Research fall term of year three of the program, after passing the Qualifying Exam.

    Course Coordinator: Student's Thesis Advisor

    Semester Offered: Fall, Spring, Summer

    Last Taught: Taught every semester

  • Graduate Research | BBS 990

    Programs: Biochemistry & Molecular Pharmacology, Bioinformatics & Computational Biology, Cancer Biology, Cell Biology, Immunology & Microbiology, Interdisciplinary, Neuroscience, Translational Science

    Students register for Graduate Research fall term of year four in the PhD Program and will continue to register each semester until they complete all remaining requirements.

    Course Coordinator: Student's Thesis Advisor

    Semester Offered: Fall, Spring, Summer

    Last Taught: Taught every semester

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