GSBS Course Offerings: Cellular & Molecular Physiology
Advanced Topics Courses
Human Physiology
Required of all first-year medical students, this course is also offered to graduate students who can elect to take the entire course or particular modules that correspond to their research interests. Modules include principles of cell physiology, endocrinology, the cardiovascular system, the pulmonary system, the renal system and the reproductive system. Catalog Number: PY702
The Cell Works: Principles of Cell Physiology
The objectives of the course are to provide a fundamental understanding of the basic biophysical principles of cell physiology; the ability to relate cellular function to whole organ physiology; and the cellular mechanisms underlying disease. By emphasizing the principles of cell physiology, the course will identify important physiological paradigms and the modern research methods used to resolve outstanding questions concerning cell function. Catalog Number: PY710
The Image Works: Principles of Light and Electron Microscopy
Principles and application of microscopy in biomedical research for graduate students at all levels. Demonstrations and laboratory exercises will be incorporated into some of the blocks of the instruction. This course is designed to teach the biologist how microscopes work and how to optimize image quality. Auditors welcome. Catalog Number: PY720a
Stimulus-Secretion Coupling: An Exo(cyto)tic Point Of View
This course deals with one of the "hottest" topics in not only Neuroscience but in cell biology: Stimulus secretion coupling, i.e., the transduction of signals from the environment into exocytotic responses. We will be studying this process in a number of organisms: viruses, yeast, sponges, drosophila, worms, mice, and even humans. Examples include sperm fertilization of eggs, asexual budding, DNA/RNA transfection, neuronal development, second-messenger mediated aggregation in slime molds, immunologoical defense, hormonal release by endocrine cells and synaptic transmission in the brain.
This field utilizes a broad synthesis of "cutting edge" techniques including molecular biology, biophysics, imaging and electrophysiology. Students will be expected to read original papers and present them in order to learn to evaulate their scientific contributions to an understanding of the molecular mechanisms underlying stimulus-secretion coupling. Catalog Number: PY720c
Cell Physiology of Excitable Membranes
This course covers the fundamental principles of cell physiology with an emphasis on ion channels, synpatic transmission, and contractile mechanisms. It is the first section of the first year Medical School Human Physiology Course and lays the foundation for understanding both cell and organ function. However, unlike the way basic science courses are reputedly taught in medical schools, this course will deal with the principles and concepts underlying cell function rather than the absorption or rote memorization of detailed factual information. The material will be introduced through a series of lectures intersprersed with a number of problem-set based conference sections, the purpose of which is to exercise and acquire an understanding of the principles.
NOTE: Intensive course. This course is a portion of the medical school curriculum. It meets for 20 classes from Jan to Feb, classes on most days Monday through Friday and with each class lasting from 1-3 hours per day. Catalog Number: PY721
Biophysicsand Molecular Basis of Membrane Conductance
This course covers the main aspects of membrane physiology and biophysics: passive membrane characteristics; gating and permeation properties of membrane channels; structure and mechanisms of control; and regulation of channels. Catalog Number: PY725
Cardiovascular Physiology
This course is designed to give the student an in-depth understanding of selected topics in cardiovascular physiology. Emphasis is placed on discussion of current literature and critical analysis of experimental design to probe unanswered questions. Catalog Number: PY730
The Body Works: Cellular and Organ Physiology
The objectives of the course are to provide a fundamental understanding of the basic biophysical principles of physiology; the relationship between cellular function and whole organ physiology; the integration and regulation of the major organ systems of the human body; and the mechanism of pathogenesis and disease. By correlating cellular processes with organ function, this course will identify important physiological paradigms and the modern research methods used to resolve outstanding questions. Catalog Number: PY750
Tutorials, Seminars and Journal Clubs
Tutorial in Cellular & Molecular Physiology
Tutorial arranged with individual faculty. Catalog Number: PY740
Seminar in Physiology
Students present seminars on topics in contemporary physiology or their research projects. Catalog Number: PY800
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