Section: Publications

Postdoctoral Position Available

Gyongyi Szabo, M.D., Ph.D.

Academic Role: Professor

Faculty Appointment(s) In:
   Gastroenterology
   Medicine

Other Affiliation(s):
   Center for AIDS Research
   Program in Immunology and Virology

Representative Publications:

1. Szabo G, Chavan S, Mandrekar P, Catalano D: 1999. Acute alcohol consumption attenuates IL-8 and MCP-1 induction in response to ex vivo stimulation. J. Clin. Immunol. 19:67-76.
2. Mandrekar P, Catalano D, Szabo G: 1999. Inhibition of LPS-mediated NF- B activation by ethanol in human monocytes. International Immunology. 11:1781-90.
3. Szabo G: 2000. New insights into the molecular mechanisms of alcoholic hepatitis: The role of NF- B activation? J. Lab. Clin. Med. 135:367-369
4. Fang WC, Saltzman J, Rososhandsky S, Szabo G, Heard S, Banner B, Katz E: 2000. Acceptance of an ABO-incomplete mismatched liver allograft with the use of Daclizumab and Mycophenolate mofetil Liver Transplantation 6:497-500
5. Szabo G, Katz E, Bonkovsky H: 2000. Management of recurrent hepatitis C after liver transplantation: a concise review Am. J. Gastroenterology 9:2164-2170.
6. Szabo G, Catalano D, Bellerose G, Mandrekar P: 2001. Interferon-alpha and alcohol augment nuclear regulatory factor- B activation in HepG2 cells and IFN increases pro-inflammatory cytokine production. Alcoholism: Clin. & Exp. Res. 25:1188-1197.
7. Szabo G, Gavala C, Mandrekar P: 2001. Tacrolimus and cyclosporine A inhibit allostimulatory capacity and cytokine production of human myeloid dendritic cells. J. Investigative Medicine. 49:442-449.
8. Szabo G, Mandrekar P, Dolganiuc A, Catalano D, Kodys K: 2001. Reduced alloreactive T cell activation after alcohol intake is due to impaired monocyte accessory cell function and correlates with elevated IL-10 and decreased IFN? levels. Alcoholism: Clin. & Exp. Res. 25(12):1766-1772.
9. Szabo G, Dolganiuc A: 2002. Immunologic marker analysis of cells in the various stages of hematopoietic differentiation. In: Clinical Applications of Immunophenotypic Analysis. Editor: K. Paloczi, R.G. Landes Co., Publisher (in press).
10. Szabo G, Romics L, Frendl G: 2002. Liver in sepsis and systemic inflammatory response syndrome. In Hepatic Manifestations of Systemic Diseases, Ed. H.L. Bonkovsky Clinics in Liver Disease Publisher: W.B. Saunders, Philadelphia (in press).
11. Drechsler Y, Mandrekar P, Chavan S, Szabo G: 2002. Fc-gamma receptor crosslinking mediates NF B activation, reduced antigen presentation capacity and IL-12 production in monocytes without inhibition of myeloid dendritic cell development. J. Leuk. Biol. (in press).
12. Szabo G & Mandrekar P: May 1, 2002. Ethanol-mediated regulation of transcription factors in immunocompetent cells. Frontiers in Bioscience 7, a80-89. (in press)

Office: Research 215
Phone: 508-856-5275
E-mail: Gyongyi.Szabo@umassmed.edu

More on Gyongyi Szabo's Research Research | Figures | Publications | Biography View All Sections on One Page

Postdoctoral Position Available Immediate opening! Two postdoctoral positions are available immediately to study cellular and molecular mechanisms resulting in immunosuppression after alcohol use. The focus of this research is the role of monocytes and dendritic cells in decreased antigen-specific T cell activation after alcohol use. Intracellular signalling mechanisms resulting in decreased NF-kB activation and inflammatory cytokine induction after acute alcohol consumption are being investigated. Please contact Dr. Szabo for details.