Section: Rotations

Christopher Sassetti, Ph.D.

Academic Role: Assistant Professor

Faculty Appointment(s) In:
   Molecular Genetics and Microbiology

Other Affiliation(s):
   Center for AIDS Research

Rotation Projects

We have identified a number of bacterial pathways that are specifically required for growth during infection, whose functions can be used to infer different aspects of the host environment.  We are particularly interested in:

1. Transmembrane transport systems that are involved in either nutrient acquisition or the export of bacterial products into the host cell.
   
2. Transcriptional regulators that are required for adaptation to the host environment.
   
3. Metabolic genes that provide information on the nutrients available to the bacterium

A variety of genetic, biochemical, and informatic methods will be used to define the functions of these genes and the role played by each during infection.

Office: S6 141
Phone: 508 856 3678
E-mail: Christopher.Sassetti@umassmed.edu
Keywords: Microbial Pathogenesis, Genomics, Tuberculosis, Infectious Disease, Genetics

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