Section: Rotations

Jack Leonard, Ph.D.

Academic Role: Professor

Faculty Appointment(s) In:
   Anesthesiology
   Physiology

Potential Rotation Projects

1. Real-time imaging of synaptic vesicle recycling will be done using cultured cerebellar granule neurons, dynamic confocal microscopy, vesicle specific fluorescent dyes, a cohort of GFP-tagged SV marker proteins. The student will learn contemporary techniques in cell and molecular neurobiology.



2. In vitro propagated cerebellar progenitor cells isolated from a family of thyroid hormone receptor mutants will be implanted into normal neonatal mice and the developmental fate of the implanted cells characterized. The student will learn immunocytochemistry, FACS analysis, and transcript profiling using Affymetrix chip technology.

Office: S4-212
Phone: 508-856-6687
E-mail: Jack.Leonard@umassmed.edu
Keywords: Neurobiology, Gene Expression, Developmental Biology

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