CFAR Members

Department, Division or Program AffiliationResearch Interests
Jeroan AllisonDepartment of Quantitative Health SciencesBehavioral interventions regarding adherence to medication in chronic disease patients
Leslie BergDepartment of PathologyT Lymphocyte Development and Activation
Diane Blake Department of PediatricsPediatric Adolescents
Dan BolonDepartment of Biochemistry and Molecular Pharmacology

 Molecular Mechanisms of Adaptation in Biology and Disease

Victor BoyartchukDepartment of Microbiology and Physiological Systems, Program in Gene Function and ExpressionStudies of the Genetic Factors Controlling Susceptibility to  Infectious Diseases using Animal Model Systems
Carol BovaGraduate School of Nursing Emerging Primary Care Needs; primary care needs of women with HIV infection; interaction of substance abuse, mental illness and adherence behaviors; HCV treatment among HIV-infected adults
Edward BoyerDepartment of Emergency MedicineHIV Prevention using Artificial Intelligence and Mobile Technology, Mobile Technology approaches to improving HAART Adherence in HIV+ Drug Users
Abraham BrassDepartment of Microbiology and Physiologic SystemsUse of functional genomics, proteomics, molecular genetics and biochemical approaches  to study host-viral interactions
Michael BrehmDepartment of Molecular Medicine Host immune responses to viral infections
Doreen Brettler Department of Medicine, Division of Hematology & Oncology Director, New England Hemophilia and Thrombosis Center
Anthony Carruthers Department of Biochemistry & Molecular PharmacologyCarrier-mediated transport
Lucio Castilla Program in Molecular Medicine, Program Gene Function & ExpressionGenetics of Leukemia, Mouse Models
Francis Chan Department of PathologyThe Role of Programmed Cell Death in Immune Functions & Diseases
Sarah Cheeseman Department of Medicine, Division of Infectious Diseases & ImmunologyAntiretroviral Therapy Clinical Trials, HIV in Pregnancy, Issues in Perinatally Infected Adolescents & Young Adults
Jason Chen Department of MedicineCell cycle checkpoints, genomic instability, and apoptosis in cells expressing papillomavirus oncogenes
Paul Clapham, Director, CFAR Developmental Core,  Co-Director, CFAR Experimental Virology CoreProgram in Molecular MedicineThe HIV envelope:  Biology, Receptors and Cellular Tropism
Michael Czech Program in Molecular MedicineRNAi-based Therapeutic Strategies for Inflammatory and Metabolic Diseases
Jennifer DalyDepartment of Medicine, Division of Infectious DiseasesClinical research in antibiotics, immune reconstitution in HIV patients, medical services utilization in HIV patients
Raul Davaro    Department of Medicine, Division of Infectious Diseases & Immunology Antiretroviral Therapy Adherence Strategies, HIV care management, Prevention and Management of Opportunistic Infections
Roger Davis Program in Molecular MedicineMechanisms by which Growth Factors regulate Cellular Proliferation
Ronald Desrosiers New England Primate Research Center (NEPRC), Harvard Medical School
Molecular Mechanisms underlying Viral Pathogenesis through the use of Monkey Models of Human Viral Diseases
Maria Jose Duenas-DecampProgram in Molecular MedicineHIV neutralization and tropism; tropism of Hematopoietic Stem Cells
Richard Ellison Department of Medicine, Division of Infectious Diseases & ImmunologyIdentification and Treatment of Nosocomial Infections
Francis Ennis Department of Medicine, Center for Infectious Disease & Vaccine ResearchImmune Response of Host to Virus Infection
David EvansNew England Primate Research Center, Harvard Universityunderstanding mechanisms of protective immunity and immune evasion using simian immunodeficiency virus (SIV) infection as an animal model for AIDS
Michael Farzan New England Primate Research Center, Harvard University HIV-1 entry into target cells, receptors or HIV-1 and other viruses
Robert Finberg Department of Medicine, Division of Infectious Diseases & ImmunologyHost-microbial Interactions
Katherine  Fitzgerald Department of Medicine, Division of Infectious Diseases and ImmunologySensing and Signaling in the Innate Immune Response
Terence Flotte           Dean, Provost and Executive Deputy Chancellor of UMass Medical School, Department of Pediatrics, Department of Microbiology and Physiological Systems, Department of Biochemistry and Molecular Pharmacology, Clinical and Population Healthalpha-1 antitrypsin (AAT) deficiency, in which lung disease develops as a consequence of loss of function and liver disease develops as a consequence of a accumulation of the mutant Pi-Z form of the AAT protein
Lisa Fortuna Department of Psychiatry Latino mental health services research, substance abuse and dual diagnoses in adolescence
Andrea Foulkes Department of Biostatistics, Public Health, UMass Amherst, MABiostatistics and Statistical Genetics
Michaela Gack New England Primate Research Center, Harvard University IFN-mediated Innate Immune Responses against viral infection
Uri Galili Department of Medicine 
Donna Gallagher New England AIDS Education and Training Center, Commonwealth Medicine, Office of Global HealthHealth Interventions and Policies
Ricardo GazzinelliDepartment of Medicine, Division of Infectious Diseases & Immunology Innate immune mechanisms and pathogenesis of protozoan infections; development of vaccines against these infections
Rachel Gerstein Department of Microbiology and Physiological SystemsDevelopmental regulations of V(D)J Recombinant and B Cell Development
Laura Gibson Department of Medicine, Division of Infectious Diseases & ImmunologyHuman T cell responses to cytomegalovirus (CMV) in children and transplant recipients
Douglas Golenbock Department of Medicine, Division of Infectious Diseases & ImmunologyToll Receptors, Sepsis and Malaria
Phil GonaDepartment of Quantitative Health SciencesStatistical and Epidemiological research in HIV/AIDS, especially opportunistic infections; global health issues of HIV/AIDS surveillance and clinical research; clinical trials for new drug development; survival and longitudinal analyses
Heinrich Gottlinger Program in Molecular Medicine, Program in Gene Function and ExpressionMolecular Biology of HIV-1
Michael Green Program in Molecular Medicine, Program in Gene Function and ExpressionEukaryotic Gene Regulation and Cancer Molecular Biology
Thomas  Greenough,   Co-Director, CFAR Translational Medicine (Clinical) Core    Department of Medicine, Division of Infectious Diseases & Immunology, PediatricsPathogenesis of HIV-1
Dale Greiner Program in Molecular Medicine

Pathogenesis of Type 1 Diabetes;
Development of unique strains of mice that can be engrafted with functional human cells and tissues, including human islets and human immune systems

Deborah Harmon-Hines Department of Cell BiologyEducation Outreach and Anatomy for Medical Education
Joonsoo KangDepartment of PathologyT Cell Lineage Commitment
Paul KaufmanDepartment of Gene Function and Expression Chromosome structure and dynamics
Michelle Kelliher Department of Cancer BiologyApoptosis and Cancer
Catarina KiefeDepartment of Quantitative Health Science Leadership in clinical and translational research, Biostatistics, Health Policy
Ellen Kittler, Coordinator, CFAR Core Lab Services, Co-Director, CFAR Molecular Biology Core
Program in Molecular  MedicineGenomic archeology of markers for disease and disease susceptibility
Hardy Kornfeld Department of Medicine, Division of Pulmonary, Allergy & Critical Care MedicineHost Defense Against Bacterial and Viral Respiratory Pathogens with Emphasis on Tuberculosis
Andrei KorostelevDepartment of Biochemistry and Molecular PharmacologyStructural understanding of the mechanisms of translation regulation during stress and disease;
the molecular basis of expression of Gag and other proteins of cellular and viral origins.
Timothy Kowalik Department of Microbiology and Physiological SystemsCell Activation and DNA Viruses
Evelyn Kurt-Jones Department of Medicine, Division of Infectious Diseases & ImmunologySignaling by Receptors on Monocytes and Macrophages that Mediate the Innate Immune Response to Bacterial and Viral Infection
David Lapointe Department of Cell BiologyBioinformatics, Gene Expression, Systems Biology
Stuart LevitzDepartment of Medicine, Division of Infectious Diseases & Immunology; Department of Microbiology and Physiological Systems Pathogenesis of opportunistic fungal pathogens and vaccine development against them
Shan Lu, CFAR Co-Director Department of MedicineImmunogenicity of Protein Antigens, HIV Vaccine Research and Development
Jeremy Luban, CFAR Co-DirectorProgram in Molecular Medicine Genetic and biochemical techniques to identify host cell factors that contribute to viral replication, pathogenesis and human immunity
Katherine Luzuriaga,  Director, CFAR Translational Medicine (Clinical) Core
 
Department of Pediatrics, Division of Infectious Diseases & Immunology, RheumatologyVirus-Host Dynamics in Persistent Viral Infections
Pranoti Mandrekar Department of Medicine, Division of GastroenterologySignaling Mechanisms in Liver Inflammation
William Marshall Department of Medicine, Division of Infectious Diseases & ImmunologyMechanisms that Viruses Employ to Evade Innate Immunity
Anuja Mathew        Department of Medicine, Division of Infectious Diseases & Immunology

Assessment of novel humanized mouse models to study immune responses to viral infections

C. Robert Matthews Department of Biochemistry and Molecular PharmacologySolving the Protein Folding Problem
Craig Mello Program in Molecular Medicine, RNA Therapeutics InstituteRegulation of gene expression during early embryogeneis in C. elegans
John Mordes Department of Medicine, Division of Endocrinology & MetabolismBasic and clinical research in type 1 diabetes
Ann Moormann Department of Pediatrics,Division of Infectious Diseases & Immunology, RheumatologyUnderstanding the Development and Maintenance of Adaptive Immunity to Infectious Diseases in Pediatric Populations, Especially During Co-Infection with Different Pathogens
Trudy Morrison Department of Microbiology and Physiological SystemsMechanisms of Paramyxovirus Membrane Fusion, Assembly of Paramyxoviruses, Development of Virus Vaccines
Mary MunsonDepartment of Biochemistry and Molecular PharmacologyMechanisms for the spatial and temporal regulation of vesicular trafficking and membrane fusion;the molecular bases of endo- and exocytosis of various cargoes, including critical HIV proteins
Peter Newburger Department of Pediatrics, Division of Hematology & OncologyNeutrophil Function and Gene Expression
Reeta Prusty Rao     Department of Biology and Biotechnology, Worcester Polytechnic InstituteFungal pathogenesis: fungal virulence factors; host immunesystem modifiers; secondary metbolite signals. High throughput screens for compounds against C. albicans
Kenneth Rock Department of Pathology

Mechanisms to Control Display of Foreign Antigens to Immune System

Ann RothsteinDepartment of Medicine, Division of Infectious Diseases & ImmunologyT and B lymphocyte activation, function, longevity and apoptosis
Christopher Sassetti Department of Microbiology and Physiological SystemsPathogenesis of Tuberculosis
Celia Schiffer, Director CFAR Program, Director, CFAR Administrative and Development CoresBiochemistry & Molecular PharmacologyStructural Basis for Molecular Recognition in HIV Protease
Liisa Selin Department of PathologyMechanisms of Viral Immunology
Ann Sheehy Biology Department, College of the Holy Cross, Worcester, MAAPOBEC3G Investigation and Resistance to viral Infection
Neal Silverman Department of Medicine, Division of Infectious Diseases & ImmunologyImmune Signaling Pathways
Mohan Somasundaran, Director, CFAR Experimental Virology CoreDepartment of PediatricsViral and Host Factors
Janet Stavnezer Department of  Microbiology and Physiological SystemsMechanism and Regulation of Antibody Class Switch Recombination
Lawrence Stern Department of PathologyMolecular Recognition in the Immune System
Caterina Strambio De Castillia Program in Molecular MedicineUnderstanding retroviral-host interactions; viral particle tracking and motion analysis; building a bioinformatics framework to support the examination of retroviral particle movement
John Sullivan Office of ResearchEpstein-Barr Virus [EBV] and Human Immunodeficiency Virus [HIV]
Susan SwainDepartment of PathologyT cell mechanisms to control and eradicate viral infections
Gyongyi Szabo Department of Medicine, Division of GastroenterologyImmune Alterations induced by Acute Alcohol Consumption
Eva Szomolanyi-Tsuda Department of PathologyInteractions of Viral Gene Products and Host Immune Systems
Jennifer WangDepartment of Medicine, Division of Infectious Diseases & Immunology Virus interactions with toll-like receptors
Shixia WangDepartment of MedicineNovel Designs of HIV-1 MPER Antigen to Elicit gp41-mediated Neutralizing Antibodies
Raymond Welsh Department of PathologyViral Immunology and Pathogenesis
Zhiping WengDepartment of Biochemistry and Molecular Pharmacology, Program in Bioinformatics and Integrative Biology Molecular mechanisms of gene regulation, Protein docking, Small silencing RNAs
Mireya Wessolossky Department of Medicine, Division of Infectious Diseases & ImmunologyClinical research in HIV/AIDS, neurocognitive issues in HIV, HCV co-infection, anal displasia
Robert Woodland Department of Microbiology and Physiological SystemsRegulation of B Cell Survival Control of Virus Expression by Lymphocyte Activators
Zuoshang Xu Department of Biochemistry & Molecular PharmacologyMechanism and Therapy of Neurodegenerative Diseases
Maria Zapp, Director, CFAR Molecular Biology CoreProgram in Molecular MedicineRegulation of Retroviral and Cellular mRNA Transport