Featured Studies

Do you suffer from pain and opioid addiction (Docket # H-14337)

We are inviting people between the ages of 18-65 who have been diagnosed with both pain and opioid addiction to participate in a 12 week research study.  Our intervention may help you reduce drug abuse and manage your pain better.  If you are eligible, you will be assigned to a group-based intervention lasting 12 weeks at no cost to you.  Participants will also be compensated.  For more information, please email opstudy@hotmail.com or call 508-334-2153.

  Study looking to enroll people who recently lost weight!  (Docket# H-00001808)

Even highly motivated individuals find it difficult to keep weight off after they have lost it. The purpose of the study is to understand brain changes that accompany participation in wellness programs for keeping weight off. We will use MRI scans to study brain function in men and women 25-55 years old who have lost weight in the last year without surgery. Participants will be assigned to one of two programs to help them maintain weight loss and will be compensated for their time. Our goal is to gain a better understanding of the brain changes that lead to long-term success in keeping weight off, in the hope that this knowledge will assist in the development of improved treatments. To find out if you may be eligible call us at 508-856-1225 or email keepitoff@umassmed.edu to find out more information.

Research study seeking healthy volunteers to complete one MRI scan
(Docket # H-00001036)

Healthy volunteers are invited to participate in an MRI research study to assess potential brain changes associated with antipsychotic treatment. This study will provide information regarding the potential effects on brain structure, function, and connectivity of antipsychotic maintenance treatment in patients with mood disorders. Study participation will entail a commitment of one study visit, and one MRI scan. Patients must be: 18 to 85 years of age; healthy without mood symptoms; not be pregnant. Compensation provided. Contact Chelsea Kosma @ 508-856-5312.

Vitamin D supplementation for Bipolar Depression (Docket # H-800)

A new research study at UMass Medical Center is evaluating Vitamin D supplementation for bipolar depression. The goal of this research is to see if Vitamin D supplementation in people with bipolar disorder is associated with improved mood, in particular less depression. The study includes questions about mood, Vitamin D level monitoring, and Vitamin D supplementation or placebo. Participants stay on their current medication regimen. This study involves seven assessments over the course of 12 weeks, and participants are compensated for their time. In order to be eligible, patients must be: 25 years old or older; diagnosed with bipolar disorder; currently feeling down, sad, or depressed; and have low Vitamin D levels (evaluated at first study visit). For more information please contact Jessica Penny (508-334-7352) or Dr. Wendy Marsh (508-856-5071)

 Investigational Drug Study for Adolescents with Schizophrenia (Docket # H-00005591)

The purpose of the study is to evaluate whether NaBen (Sodium Benzoate) is an effective add-on treatment for adolescents with schizophrenia.  Who can participate? Adolescents between 12 and 16 years of age who have been diagnosed with schizophrenia.  Participants need to be on a stable antipsychotic treatment for their schizophrenia and still be experiencing residual symptoms.  How will participants be compensated? Compensation will be provided for time and travel. For more information, contact CANDI at (774) 455-4100.

 MRI with children and adolescents diagnosed with Fragile X or Down Syndrome (Docket # H-00002894)

The purpose of the study is to determine if we can find ways to help children undergo MRI without needing to be sedated. We are especially interested in learning ways to help children with developmental disabilities, such as Fragile X syndrome and Down syndrome with having an MRI. We also hope to learn more about the features of the brains of children and adolescents aged 7-17 with Fragile X or Down syndrome.  Participation in this study will last up to approximately 1½ months and requires 2 visits to the University of Massachusetts Medical School. There will also be some activities that for you to use at home with your child to prepare him or her for MRI. These activities take about 10 to 15 minutes and can be repeated as often as you feel necessary. For each visit to the office, a small payment will be offered to offset travel expenses. All study-related evaluations are provided at no cost. 

Eligibility:  Males or females between 7 and 17 years of age; diagnosis of Fragile X syndrome or Down syndrome.  Parent willing to assist with desensitization activities at home.  If you are interested in learning more about this study, please contact: Child and Adolescent Neurodevelopment Initiative (CANDI) (508) 856-5896 or ChildResearch@umassmed.edu




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