Recent Publications

The authors names are linked to the PubMed abstract of each article.

2010

• Rothman AL. Cellular immunology of sequential dengue virus infection and its role in disease pathogenesis. Curr Top Microbiol Immunol 2010; 338:83-98.
• Srikiatkhachorn A, Green S. Markers of dengue disease severity. Curr Top Microbiol Immunol 2010; 338:67-82.

2009

• Srikiatkhachorn A. Plasma leakage in dengue haemorrhagic fever. Thromb Haemost 2009; 102:1042-1049
• Thomas SJ, Nisalak A, Anderson KB, Libraty DH, Kalayanarooj S, Vaughn DW, Putnak R, Gibbons RV, Jarman R, Endy TP. Dengue plaque reduction neutralization test (PRNT) in primary and secondary dengue virus infections: How alterations in assay conditions impact performance. Am J Trop Med Hyg 2009; 81:825-833.
• Libraty DH, Acosta LP, Tallo V, Segubre-Mercado E, Bautista A, Potts JA, Jarman RG, Yoon IK, Gibbons RV, Brion JD, Capeding RZ. A prospective nested case-control study of dengue in infants: rethinking and refining the antibody-dependent enhancement dengue hemorrhagic fever model. PLoS Med 2009; 6:e1000171.
• Houghton-Triviño N, Salgado DM, Rodriguez JA, Bosch I, Castellanos JE. Levels of soluble ST2 in serum associate with severity of dengue due to TNF-{alpha} stimulation. J Gen Virol 2009.
• Jaiswal S, Pearson T, Friberg H, Shultz LD, Greiner DL, Rothman AL, Mathew A. Dengue virus infection and virus-specific HLA-A2 restricted immune responses in humanized NOD-scid IL2rgammanull mice. PLoS One 2009; 4:e7251.
• Co MD, Kilpatrick ED, Rothman AL. Dynamics of the CD8 T-cell response following yellow fever virus 17D immunization. Immunology 2009; 128:e718-727.
• Rothman AL. T lymphocyte responses to heterologous secondary dengue virus infections. Ann N Y Acad Sci 2009; 1171:E36-41.
• Becerra A, Warke RV, Martin K, Xhaja K, de Bosch N, Rothman AL, Bosch I. Gene expression profiling of dengue infected human primary cells identifies secreted mediators in vivo. J Med Virol 2009; 81:1403-1411.
• Liu P, Woda M, Ennis FA, Libraty DH. Dengue virus infection differentially regulates endothelial barrier function over time through type I interferon effects. J Infect Dis 2009; 200:191-201.
• Babon JA, Cruz J, Orphin L, Pazoles P, Co MD, Ennis FA, Terajima M. Genome-wide screening of human T-cell epitopes in influenza A virus reveals a broad spectrum of CD4(+) T-cell responses to internal proteins, hemagglutinins, and neuraminidases. Hum Immunol 2009; 70:711-721.
• Beaumier CM, Rothman AL. Cross-reactive memory CD4+ T cells alter the CD8+ T-cell response to heterologous secondary dengue virus infections in mice in a sequence-specific manner. Viral Immunol 2009; 22:215-219.
• Vejbaesya S, Luangtrakool P, Luangtrakool K, Kalayanarooj S, Vaughn DW, Endy TP, Mammen MP, Green S, Libraty DH, Ennis FA, Rothman AL, Stephens HA. TNF and LTA Gene, Allele, and Extended HLA Haplotype Associations with Severe Dengue Virus Infection in Ethnic Thais. J Infect Dis 2009; 199:1442-1448.
• Becerra A, Warke RV, Xhaja K, Evans B, Evans J, Martin K, de Bosch N, Rothman AL, Bosch I. Increased activity of indoleamine 2,3-dioxygenase in serum from acutely infected dengue patients linked to gamma interferon antiviral function. J Gen Virol 2009; 90:810-817.
• Co MD, Orphin L, Cruz J, Pazoles P, Green KM, Potts J, Leporati AM, Babon JA, Evans JE, Ennis FA, Terajima M. In vitro evidence that commercial influenza vaccines are not similar in their ability to activate human T cell responses. Vaccine 2009; 27:319-327.

2008

• Terajima M, Orphin L, Leporati AM, Pazoles P, Cruz J, Rothman AL, Ennis FA. Vaccinia virus-specific CD8+ T cell responses target a group of epitopes without a strong immunodominance hierarchy in humans. Human Immunol 2008; 69:815-825.
• Mammen MP Jr, Pimgate C, Koenraadt CJM, Rothman AL, Aldstadt J, Nisalak A, Ypil-Butac CA, Klungthong C, Thaisomboonsuk B, Jarman RG, Jones JW, Zhang C, Srikiatkhachorn A, Gibbons RV, Thammapalo S, Getis A, Endy TP, Morrison AC, Libraty DH, Ennis FA, Green S, Scott TW. Spatial and temporal focality of dengue virus transmission in Thai villages revealed by cluster investigations. PLoS Med 2008; 5:e205.
• Mathew A, Rothman AL. Understanding the contribution of cellular immunity to dengue disease pathogenesis. Immunol Rev 2008; 225:300-313.
• Mathew A, O’Bryan J, Marshall W, Terajima M, Green S, Rothman AL, Ennis FA. Robust intrapulmonary CD8 T cell responses with N1L deleted but not wild type vaccinia viruses. PLoS ONE 2008; 3:e3323.
• Potts JA, Rothman AL. Clinical and laboratory features that distinguish dengue from other febrile illnesses in endemic populations: a systematic review. Trop Med Int Health 2008; 13:1328-1340.
• Nightingale ZN, Patkar C, Rothman AL. Viral replication and paracrine effects result in distinct functional responses of dendritic cells following infection with dengue 2 virus. J Leukoc Biol 2008; 84:1028-1038.
• Pavlin JA, Hickey AC, Ulbrandt N, Chan YP, Endy TP, Boukhvalova MS, Chunsuttiwat S, Nisalak A, Libraty DH, Green S, Rothman AL, Ennis FA, Jarman R, Gibbons RV, Broder CC. Human metapneumovirus reinfection among children in Thailand determined by an enzyme-linked immunosorbent assay using purified soluble fusion protein. J Infect Dis 2008; 198:836-842.
• Putnak JR, de la Barrera R, Burgess T, Pardo J, Dessy F, Gheysen D, Lobet Y, Green S, Endy TP, Thomas SJ, Eckels KH, Innis BL, Sun W. Comparative evaluation of three assays for measurement of dengue virus neutralizing antibodies. Am J Trop Med Hyg 2008; 79:115-122.
• Kennedy JS, Co M, Green S, Longtine K, Longtine J, O’Neill MA, Adams JP, Rothman AL, Yu Q, Johnson-Leva R, Pal R, Wang S, Lu S, Markham P. The safety and tolerability of an HIV-1 DNA prime-protein boost vaccine (DP6-001) in healthy adult volunteers. Vaccine 2008; 4420-4424.
• Terajima M, Cruz J, Leporati AM, Orphin L, Babon JA, Co MD, Pazoles P, Jameson J, Ennis FA. Influenza A virus matrix protein 1-specific human CD8+ T-cell response induced in trivalent inactivated vaccine recipients. J Virol 2008; 82:9283-9287.
• Warke RV, Becerra A, Zawadzka A, Schmidt DJ, Martin KJ, Giaya K, Dinsmore JH, Woda M, Hendricks G, Levine T, Rothman AL, Bosch I. Efficient dengue virus (DENV) infection of human muscle satellite cells upregulates type I interferon response genes and differentially modulates MHC I expression on bystander and DENV-infected cells. J Gen Virol 2008; 89:1605-1615.
• Strug I, Calvo-Calle JM, Green KM, Cruz J, Ennis FA, Evans JE, Stern LJ. Vaccinia peptides eluted from HLA-DR1 isolated from virus-infected cells are recognized by CD4(+) T cells from a vaccinated donor. J Proteome Res 2008; 7:2703-2711.
• Zota V, Angelis SM, Fraire AE, McNamee C, Kielbasa S, Libraty DH. Lessons from Mycobacterium avium complex-associated pneumonitis: a case report. J Med Case Reports 2008; 2:152.
• Jarman RG, Holmes EC, Rodpradit P, Klungthong C, Gibbons RV, Nisalak A, Rothman AL, Libraty DH, Ennis FA, Mammen MP Jr, Endy TP. Microevolution of dengue viruses circulating among primary school children in Kamphaeng Phet, Thailand. J Virol 2008; 82:5494-5500.
• Co MD, Orphin L, Cruz J, Pazoles P, Rothman AL, Ennis FA, Terajima M. Discordance between antibody and T cell responses in recipients of trivalent inactivated influenza vaccine. Vaccine 2008; 26:1990-1998.
• Beaumier CM, Mathew A, Bashyam HS, Rothman AL. Cross-reactive memory CD8(+) T cells alter the immune response to heterologous secondary dengue virus infections in mice in a sequence-specific manner. J Infect Dis 2008; 197:608-617.
• Wang S, Kennedy JS, West K, Montefiori DC, Coley S, Lawrence J, Shen S, Green S, Rothman AL, Ennis FA, Arthos J, Pal R, Markham P, Lu S. Cross-subtype antibody and cellular immune responses induced by a polyvalent DNA prime-protein boost HIV-1 vaccine in healthy human volunteers. Vaccine 2008; 26:3947-3957.
• Becerra A, Warke RV, de Bosch N, Rothman AL, Bosch I. Elevated levels of soluble ST2 protein in dengue virus infected patients. Cytokine 2008; 41:114-120.
• Hatch S, Mathew A, Rothman AL. Dengue vaccine: opportunities and challenges. IDrugs 2008; 11:42-45.
• Warke RV, Martin KJ, Giaya K, Shaw SK, Rothman AL, Bosch I. TRAIL is a novel antiviral protein against dengue virus. J Virol 2008; 82:555-564.

2007

• Frey SE, Newman FK, Kennedy JS, Sobek V, Ennis FA, Hill H, Yan LK, Chaplin P, Vollmar J, Chaitman BR, Belshe RB. Clinical and immunologic responses to multiple doses of IMVAMUNE (Modified Vaccinia Ankara) followed by Dryvax challenge. Vaccine 2007; 25:8562-8573.
• Libraty DH, Myint KS, Murray CK, Gibbons RV, Mammen MP, Endy TP, Li W, Vaughn DW, Nisalak A, Kalayanarooj S, Hospenthal DR, Green S, Rothman AL, Ennis FA. A comparative study of leptospirosis and dengue in Thai children. PLoS Negl Trop Dis 2007; 1:e111.
• Frey SE, Newman FK, Kennedy JS, Sobek V, Ennis FA, Hill H, Yan LK, Chaplin P, Vollmar J, Chaitman BR, Belshe RB. Clinical and immunologic responses to multiple doses of IMVAMUNE((R)) (Modified Vaccinia Ankara) followed by Dryvax((R)) challenge. Vaccine 2007; 25:8562-8573.
• Gibbons RV, Kalanarooj S, Jarman RG, Nisalak A, Vaughn DW, Endy TP, Mammen MP Jr, Srikiatkhachorn A. Analysis of repeat hospital admissions for dengue to estimate the frequency of third or fourth dengue infections resulting in admissions and dengue hemorrhagic fever, and serotype sequences. Am J Trop Med Hyg 2007; 77:910-913.
• Terajima M, Hayasaka D, Maeda K, Ennis FA. Immunopathogenesis of hantavirus pulmonary syndrome and hemorrhagic fever with renal syndrome: Do CD8(+) T cells trigger capillary leakage in viral hemorrhagic fevers? Immunol Lett 2007; 113:117-120.
• Libraty DH, O'Neil KM, Baker LM, Acosta LP, Olveda RM. Human CD4(+) memory T-lymphocyte responses to SARS coronavirus infection. Virology 2007; 368:317-321.
• Tuuminen T, Kekalainen E, Makela S, Ala-Houhala I, Ennis FA, Hedman K, Mustonen J, Vaheri A, Arstila TP. Human CD8+ T cell memory generation in Puumala hantavirus infection occurs after the acute phase and is associated with boosting of EBV-specific CD8+ memory T cells. J Immunol 2007; 179:1988-1995.
• Mitra-Kaushik S, Cruz J, Stern LJ, Ennis FA, Terajima M. Human cytotoxic CD4+ T cells recognize HLA-DR1-restricted epitopes on vaccinia virus proteins A24R and D1R conserved among poxviruses. J Immunol 2007; 179:1303-1312.
• Bosch I, Herrera F, Navarro JC, Lentino M, Dupuis A, Maffei J, Jones M, Fernández E, Pérez N, Pérez-Emán J, Guimarães AE, Barrera R, Valero N, Ruiz J, Velásquez G, Martinez J, Comach G, Komar N, Spielman A, Kramer L. West Nile virus, Venezuela. Emerg Infect Dis 2007; 13:651-653.
• Anderson KB, Chunsuttiwat S, Nisalak A, Mammen MP, Libraty DH, Rothman AL, Green S, Vaughn DW, Ennis FA, Endy TP. Burden of symptomatic dengue infection in children at primary school in Thailand: a prospective study. Lancet 2007; 369:1452-1459.
• Srikiatkhachorn A, Krautrachue A, Ratanaprakarn W, Wongtapradit L, Nithipanya N, Kalayanarooj S, Nisalak A, Thomas SJ, Gibbons RV, Mammen MP Jr, Libraty DH, Ennis FA, Rothman AL, Green S. Natural history of plasma leakage in dengue hemorrhagic fever: a serial ultrasonographic study. Pediatr Infect Dis J 2007; 26:283-290.
• Sivapalasingam S, Kennedy JS, Borkowsky W, Valentine F, Zhan MX, Pazoles P, Paolino A, Ennis FA, Steigbigel NH. Immunological memory after exposure to variola virus, monkeypox virus, and vaccinia virus. J Infect Dis 2007; 195:1151-1159.
• Hayasaka D, Ennis FA, Terajima M. Pathogeneses of respiratory infections with virulent and attenuated vaccinia viruses. Virol J 2007; 4:22.
• Laoprasopwattana K, Libraty DH, Endy TP, Nisalak A, Chunsuttiwat S, Ennis FA, Rothman AL, Green S. Antibody-dependent cellular cytotoxicity mediated by plasma obtained before secondary dengue virus infections: potential involvement in early control of viral replication. J Infect Dis 2007; 195:1108-1116.
• Kalayanarooj S, Gibbons RV, Vaughn D, Green S, Nisalak A, Jarman RG, Mammen MP Jr, Perng GC. Blood group AB is associated with increased risk for severe dengue disease in secondary infections. J Infect Dis 2007; 195:1014-1017.
• Hayasaka D, Maeda K, Ennis FA, Terajima M. Increased permeability of human endothelial cell line EA.hy926 induced by hantavirus-specific cytotoxic T lymphocytes. Virus Res 2007; 123:120-127.
• Srikiatkhachorn A, Ajariyakhajorn C, Endy TP, Kalayanarooj S, Libraty DH, Green S, Ennis FA, Rothman AL. Virus-induced decline in soluble vascular endothelial growth receptor 2 is associated with plasma leakage in dengue hemorrhagic fever. J Virol 2007; 81:1592-1600.