Section: Research

Masanori Terajima, Ph.D.,M.D.

Academic Role: Associate Professor

Faculty Appointment(s) In:
   Medicine

Other Affiliation(s):
   Center for Infectious Disease and Vaccine Research
   Program in Immunology and Virology

Host Immune Responses Against Viruses

Our research interest is host (especially human) immune responses against viruses.

We are studying (1) immune responses to influenza viruses (2) antiviral genes against vaccinia virus, (3) Immunopathogenesis of hantavirus infections.

(1) Immune responses to influenza viruses

We are studying humoral and cellular immune responses to influenza virus infection and vaccination with emphasis on subtype cross-reactive T cell responses in humans.

(2) antiviral genes against vaccinia virus

We are studying host range genes in vaccinia to understand the mechanisms of species specificity and to identify new antiviral mechanisms.

(3) Immunopathogenesis of hantavirus infections

Hantavirus infection causes two clinically different diseases, hantavirus pulmonary syndrome (HPS) and hemorrhagic fever renal syndrome (HFRS) depending on the hantavirus species infecting the patients. We are studying immunopathological mechanisms of these diseases focusing on the virus-specific T cells-endothelial cells interaction.

Office: S6-714
Phone: 508-856-6854
E-mail: Masanori.Terajima@umassmed.edu
Keywords: Immunology, Viral Infections and Immunity, Infectious Disease, Vaccine, Viral Pathogenesis

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