CFAR Members

 

 CFAR Members

Department, Division or Program Affiliation Research Interests
Jeroan Allison Department of Quantitative Health Sciences Behavioral interventions regarding adherence to medication in chronic disease patients
Leslie Berg Department of Pathology T Lymphocyte Development and Activation
Diane Blake Department of Pediatrics Pediatric Adolescents
Dan Bolon Department of Biochemistry and Molecular Pharmacology

 Molecular Mechanisms of Adaptation in Biology and Disease

Victor Boyartchuk Department of Microbiology and Physiological Systems, Program in Gene Function and Expression Studies of the Genetic Factors Controlling Susceptibility to  Infectious Diseases using Animal Model Systems
Carol Bova Graduate School of Nursing  Emerging Primary Care Needs; primary care needs of women with HIV infection; interaction of substance abuse, mental illness and adherence behaviors; HCV treatment among HIV-infected adults
Edward Boyer Department of Emergency Medicine HIV Prevention using Artificial Intelligence and Mobile Technology, Mobile Technology approaches to improving HAART Adherence in HIV+ Drug Users
Abraham Brass Department of Microbiology and Physiologic Systems Use of functional genomics, proteomics, molecular genetics and biochemical approaches  to study host-viral interactions
Michael Brehm Department of Molecular Medicine  Host immune responses to viral infections
Doreen Brettler  Department of Medicine, Division of Hematology & Oncology  Director, New England Hemophilia and Thrombosis Center
Anthony Carruthers  Department of Biochemistry & Molecular Pharmacology Carrier-mediated transport
Lucio Castilla  Program in Molecular Medicine, Program Gene Function & Expression Genetics of Leukemia, Mouse Models
Francis Chan  Department of Pathology The Role of Programmed Cell Death in Immune Functions & Diseases
Sarah Cheeseman  Department of Medicine, Division of Infectious Diseases & Immunology Antiretroviral Therapy Clinical Trials, HIV in Pregnancy, Issues in Perinatally Infected Adolescents & Young Adults
Jason Chen  Department of Medicine Cell cycle checkpoints, genomic instability, and apoptosis in cells expressing papillomavirus oncogenes
Paul Clapham, Director, CFAR Developmental Core,  Co-Director, CFAR Experimental Virology Core Program in Molecular Medicine The HIV envelope:  Biology, Receptors and Cellular Tropism
Michael Czech  Program in Molecular Medicine RNAi-based Therapeutic Strategies for Inflammatory and Metabolic Diseases
Jennifer Daly Department of Medicine, Division of Infectious Diseases Clinical research in antibiotics, immune reconstitution in HIV patients, medical services utilization in HIV patients
Raul Davaro     Department of Medicine, Division of Infectious Diseases & Immunology  Antiretroviral Therapy Adherence Strategies, HIV care management, Prevention and Management of Opportunistic Infections
Roger Davis  Program in Molecular Medicine Mechanisms by which Growth Factors regulate Cellular Proliferation
Ronald Desrosiers  New England Primate Research Center (NEPRC), Harvard Medical School
Molecular Mechanisms underlying Viral Pathogenesis through the use of Monkey Models of Human Viral Diseases
Maria Jose Duenas-Decamp Program in Molecular Medicine HIV neutralization and tropism; tropism of Hematopoietic Stem Cells
Richard Ellison  Department of Medicine, Division of Infectious Diseases & Immunology Identification and Treatment of Nosocomial Infections
Francis Ennis  Department of Medicine, Center for Infectious Disease & Vaccine Research Immune Response of Host to Virus Infection
David Evans New England Primate Research Center, Harvard University understanding mechanisms of protective immunity and immune evasion using simian immunodeficiency virus (SIV) infection as an animal model for AIDS
Michael Farzan  New England Primate Research Center, Harvard University  HIV-1 entry into target cells, receptors or HIV-1 and other viruses
Robert Finberg  Department of Medicine, Division of Infectious Diseases & Immunology Host-microbial Interactions
Katherine  Fitzgerald  Department of Medicine, Division of Infectious Diseases and Immunology Sensing and Signaling in the Innate Immune Response
Terence Flotte            Dean, Provost and Executive Deputy Chancellor of UMass Medical School, Department of Pediatrics, Department of Microbiology and Physiological Systems, Department of Biochemistry and Molecular Pharmacology, Clinical and Population Health alpha-1 antitrypsin (AAT) deficiency, in which lung disease develops as a consequence of loss of function and liver disease develops as a consequence of a accumulation of the mutant Pi-Z form of the AAT protein
Lisa Fortuna  Department of Psychiatry  Latino mental health services research, substance abuse and dual diagnoses in adolescence
Andrea Foulkes  Department of Biostatistics, Public Health, UMass Amherst, MA Biostatistics and Statistical Genetics
Michaela Gack  New England Primate Research Center, Harvard University  IFN-mediated Innate Immune Responses against viral infection
Uri Galili  Department of Medicine  
Donna Gallagher  New England AIDS Education and Training Center, Commonwealth Medicine, Office of Global Health Health Interventions and Policies
Ricardo Gazzinelli Department of Medicine, Division of Infectious Diseases & Immunology  Innate immune mechanisms and pathogenesis of protozoan infections; development of vaccines against these infections
Rachel Gerstein  Department of Microbiology and Physiological Systems Developmental regulations of V(D)J Recombinant and B Cell Development
Laura Gibson  Department of Medicine, Division of Infectious Diseases & Immunology Human T cell responses to cytomegalovirus (CMV) in children and transplant recipients
Douglas Golenbock  Department of Medicine, Division of Infectious Diseases & Immunology Toll Receptors, Sepsis and Malaria
Phil Gona Department of Quantitative Health Sciences Statistical and Epidemiological research in HIV/AIDS, especially opportunistic infections; global health issues of HIV/AIDS surveillance and clinical research; clinical trials for new drug development; survival and longitudinal analyses
Heinrich Gottlinger  Program in Molecular Medicine, Program in Gene Function and Expression Molecular Biology of HIV-1
Michael Green  Program in Molecular Medicine, Program in Gene Function and Expression Eukaryotic Gene Regulation and CancerMolecular Biology
Thomas  Greenough,   Co-Director, CFAR Translational Medicine (Clinical) Core     Department of Medicine, Division of Infectious Diseases & Immunology, Pediatrics Pathogenesis of HIV-1
Dale Greiner  Program in Molecular Medicine

Pathogenesis of Type 1 Diabetes;
Development of unique strains of mice that can be engrafted with functional human cells and tissues, including human islets and human immune systems

Deborah Harmon-Hines  Department of Cell Biology Education Outreach and Anatomy for Medical Education
Joonsoo Kang Department of Pathology T Cell Lineage Commitment
Paul Kaufman Department of Gene Function and Expression  Chromosome structure and dynamics
Michelle Kelliher  Department of Cancer Biology Apoptosis and Cancer
Catarina Kiefe Department of Quantitative Health Science  Leadership in clinical and translational research, Biostatistics, Health Policy
Ellen Kittler, Coordinator, CFAR Core Lab Services, Co-Director, CFAR Molecular Biology Core Program in Molecular  Medicine Genomic archeology of markers for disease and disease susceptibility
Hardy Kornfeld  Department of Medicine, Division of Pulmonary, Allergy & Critical Care Medicine Host Defense Against Bacterial and Viral Respiratory Pathogens with Emphasis on Tuberculosis
Andrei Korostelev Department of Biochemistry and Molecular Pharmacology Structural understanding of the mechanisms of translation regulation during stress and disease;
the molecular basis of expression of Gag and other proteins of cellular and viral origins.
Timothy Kowalik  Department of Microbiology and Physiological Systems Cell Activation and DNA Viruses
Evelyn Kurt-Jones  Department of Medicine, Division of Infectious Diseases & Immunology Signaling by Receptors on Monocytes and Macrophages that Mediate the Innate Immune Response to Bacterial and Viral Infection
David Lapointe  Department of Cell Biology Bioinformatics, Gene Expression, Systems Biology
Stuart Levitz Department of Medicine, Division of Infectious Diseases & Immunology; Department of Microbiology and Physiological Systems  Pathogenesis of opportunistic fungal pathogens and vaccine development against them
Shan Lu, CFAR Co-Director  Department of Medicine Immunogenicity of Protein Antigens, HIV Vaccine Research and Development
Jeremy Luban, CFAR Co-Director Program in Molecular Medicine  Genetic and biochemical techniques to identify host cell factors that contribute to viral replication, pathogenesis and human immunity
Katherine Luzuriaga,  Director, CFAR Translational Medicine (Clinical) Core
 
Department of Pediatrics, Division of Infectious Diseases & Immunology, Rheumatology Virus-Host Dynamics in Persistent Viral Infections
Pranoti Mandrekar  Department of Medicine, Division of Gastroenterology Signaling Mechanisms in Liver Inflammation
William Marshall  Department of Medicine, Division of Infectious Diseases & Immunology Mechanisms that Viruses Employ to Evade Innate Immunity
Anuja Mathew         Department of Medicine, Division of Infectious Diseases & Immunology

Assessment of novel humanized mouse models to study immune responses to viral infections

C. Robert Matthews  Department of Biochemistry and Molecular Pharmacology Solving the Protein Folding Problem
Craig Mello  Program in Molecular Medicine, RNA Therapeutics Institute Regulation of gene expression during early embryogeneis in C. elegans
John Mordes  Department of Medicine, Division of Endocrinology & Metabolism Basic and clinical research in type 1 diabetes
Ann Moormann  Department of Pediatrics,Division of Infectious Diseases & Immunology, Rheumatology Understanding the Development and Maintenance of Adaptive Immunity to Infectious Diseases in Pediatric Populations, Especially During Co-Infection with Different Pathogens
Trudy Morrison  Department of Microbiology and Physiological Systems Mechanisms of Paramyxovirus Membrane Fusion, Assembly of Paramyxoviruses, Development of Virus Vaccines
Mary Munson Department of Biochemistry and Molecular Pharmacology Mechanisms for the spatial and temporal regulation of vesicular trafficking and membrane fusion;the molecular bases of endo- and exocytosis of various cargoes, including critical HIV proteins
Peter Newburger  Department of Pediatrics, Division of Hematology & Oncology Neutrophil Function and Gene Expression
Reeta Prusty Rao      Department of Biology and Biotechnology, Worcester Polytechnic Institute Fungal pathogenesis: fungal virulence factors; host immunesystem modifiers; secondary metbolite signals. High throughput screens for compounds against C. albicans
Kenneth Rock  Department of Pathology

Mechanisms to Control Display of ForeignAntigens to Immune System

Ann Rothstein Department of Medicine, Division of Infectious Diseases & Immunology T and B lymphocyte activation, function, longevity and apoptosis
Christopher Sassetti  Department of Microbiology and Physiological Systems Pathogenesis of Tuberculosis
Celia Schiffer, Director CFAR Program, Director, CFAR Administrative and Development Cores Biochemistry & Molecular Pharmacology Structural Basis for Molecular Recognition in HIV Protease
Liisa Selin  Department of Pathology Mechanisms of Viral Immunology
Ann Sheehy  Biology Department, College of the Holy Cross, Worcester, MA APOBEC3G Investigation and Resistance to viral Infection
Neal Silverman  Department of Medicine, Division of Infectious Diseases & Immunology Immune Signaling Pathways
Mohan Somasundaran, Director, CFAR Experimental Virology Core Department of Pediatrics Viral and Host Factors
Janet Stavnezer  Department of  Microbiology and Physiological Systems Mechanism and Regulation of Antibody Class Switch Recombination
Lawrence Stern  Department of Pathology Molecular Recognition in the Immune System
Caterina Strambio De Castillia Program in Molecular Medicine Understanding retroviral-host interactions; viral particle tracking and motion analysis; building a bioinformatics framework to support the examination of retroviral particle movement
John Sullivan  Office of Research Epstein-Barr Virus [EBV] and Human Immunodeficiency Virus [HIV]
Susan Swain Department of Pathology T cell mechanisms to control and eradicate viral infections
Gyongyi Szabo  Department of Medicine, Division of Gastroenterology Immune Alterations induced by Acute Alcohol Consumption
Eva Szomolanyi-Tsuda  Department of Pathology Interactions of Viral Gene Products and Host Immune Systems
Jennifer Wang Department of Medicine, Division of Infectious Diseases & Immunology  Virus interactions with toll-like receptors
Shixia Wang Department of Medicine Novel Designs of HIV-1 MPER Antigen to Elicit gp41-mediated Neutralizing Antibodies
Raymond Welsh  Department of Pathology Viral Immunology and Pathogenesis
Zhiping Weng Department of Biochemistry and Molecular Pharmacology, Program in Bioinformatics and Integrative Biology  Molecular mechanisms of gene regulation, Protein docking, Small silencing RNAs
Mireya Wessolossky  Department of Medicine, Division of Infectious Diseases & Immunology Clinical research in HIV/AIDS, neurocognitive issues in HIV, HCV co-infection, anal displasia
Robert Woodland  Department of Microbiology and Physiological Systems Regulation of B Cell Survival Control of Virus Expression by Lymphocyte Activators
Zuoshang Xu  Department of Biochemistry & Molecular Pharmacology Mechanism and Therapy of Neurodegenerative Diseases
Maria Zapp, Director, CFAR Molecular Biology Core Program in Molecular Medicine Regulation of Retroviral and Cellular mRNA Transport