Section: Publications

Peter Pryciak, Ph.D.

Academic Role: Associate Professor

Faculty Appointment(s) In:
   Molecular Genetics and Microbiology

Other Affiliation(s):
   Cell Dynamics Group
   Interdisciplinary Graduate Program

Recent Publications

Takahashi, S., and Pryciak, P.M. (2008).  Membrane localization of scaffold proteins promotes graded signaling in the yeast MAP kinase cascade.  Curr. Biol. 18: 1184-1191.   LINK

Pryciak, P.M. (2008).  Systems biology: customized signaling circuits.  Science 319: 1489-1490.  LINK

Strickfaden, S.C., and Pryciak, P.M. (2008).  Distinct roles for two Ga-Gb interfaces in cell polarity control by a yeast heterotrimeric G protein.  Mol. Biol. Cell  19: 181-197.  LINK

Takahashi, S., and Pryciak, P.M. (2007).  Identification of novel membrane-binding domains in multiple yeast Cdc42 effectors.  Mol. Biol. Cell 18: 4945-4956.  LINK

Strickfaden, S.C., Winters, M.J., Ben-Ari, G., Lamson, R.E., Tyers, M., and Pryciak, P.M. (2007).  A mechanism for cell-cycle regulation of MAP kinase signaling in a yeast differentiation pathway.  Cell 128: 519-531.  LINK

Lamson, R.E., Takahashi, S., Winters, M.J., and Pryciak, P.M. (2006).  Dual role for membrane localization in yeast MAP kinase cascade activation and its contribution to signaling fidelity.  Curr. Biol. 16: 618-623.  LINK

Winters, M.J., Lamson, R.E., Nakanishi, H., Neiman, A.M., and Pryciak, P.M. (2005).  A membrane binding domain in the Ste5 scaffold synergizes with Gbg binding to control localization and signaling in pheromone response.  Mol. Cell 20: 21-32.  LINK

Winters, M.J., and Pryciak, P.M. (2005).  Interaction with the SH3 domain protein Bem1 regulates signaling by the Saccharomyces cerevisiae p21-activated kinase Ste20.  Mol. Cell. Biol. 25: 2177-2190.  LINK

Lamson, R.E., Winters, M.J., and Pryciak, P.M. (2002).  Cdc42 regulation of kinase activity and signaling by the yeast p21-activated kinase Ste20.  Mol. Cell. Biol. 22: 2939-2951.  LINK

Pryciak, P.M. (2001)  MAP kinases bite back.  Dev. Cell  1: 449-451.  LINK

Harris, K., Lamson, R.E., Nelson, B., Hughes, T.R., Marton, M.J., Roberts, C.J., Boone, C., and Pryciak, P.M.  (2001).  Role of scaffolds in MAP kinase pathway specificity revealed by custom design of pathway-dedicated signaling proteins.  Curr. Biol.  11: 1815-1824.  LINK

Moskow, J.J., Gladfelter, A.S., Lamson, R.E., Pryciak, P.M., and Lew, D.J. (2000). Role of Cdc42p in pheromone-stimulated signal transduction in Saccharomyces cerevisiae.  Mol. Cell. Biol. 20: 7559-7571.  LINK

Butty, A.-C., Pryciak, P.M., Huang, L.S., Herskowitz, I. and Peter, M. (1998). The role of Far1p in linking the heterotrimeric G protein to polarity establishment proteins during yeast mating. Science 282: 1511-1516.  LINK

Pryciak, P.M. and Huntress, F.A. (1998). Membrane recruitment of the kinase cascade scaffold protein Ste5 by the Gbg complex underlies activation of the yeast pheromone response pathway. Genes Dev. 12: 2684-2697.  LINK

Office: Bio IV Rm# 330
Phone: 508-856-8756
E-mail: Peter.Pryciak@umassmed.edu
Keywords: Signal Transduction, Cell Dynamics, Yeast, Cell Biology, Genetics

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