Section: Publications

Gregory Pazour, Ph.D.

Academic Role: Associate Professor

Faculty Appointment(s) In:
   Program in Molecular Medicine

Other Affiliation(s):
   Cell Dynamics Group
   Interdisciplinary Graduate Program
   Physiology

Representative Publications

See http://users.umassmed.edu/gregory.pazour/for a complete list.

Jonassen, J., SanAgustin, J., Follit, J.A. and Pazour, G.J.. 2008. “Deletion of IFT20 in the Mouse Kidney Causes Misorientation of the Mitotic Spindle and Cystic Kidney Disease”  J. Cell Biol. in press.

Merchant et al., 2007 “The Chlamydomonas genome reveals the evolution of key animal and plant functions" Science. 318:245-50.

Follit, J.A., Tuft, R.A., Fogarty, K.E., and Pazour, G.J. 2006.  The intraflagellar transport protein IFT20 is associated with the Golgi complex and is required for cilia assembly.   Mol. Biol. Cell, 17:3781-3792.

Pazour, G.J., Agrin, N., Leszyk, J., and Witman, G.B. 2005.  Proteomic characterization of a eukaryotic cilium. J. Cell Biol. 170:103-113.

Pazour, G.J., Baker, S., Deane, J., Cole, D.G., Dickert, B.L., Rosenbaum, J.L., Witman, G.B., and Besharse, J. 2002. The intraflagellar transport protein, IFT88, is essential for vertebrate photoreceptor assembly and maintenance. J. Cell Biol. 157: 103-113.

Pazour, G.J., San Agustin, J.T., Follit, J.A., Rosenbaum, J.L., and Witman, G.B., 2002. Polycystin-2 localizes to kidney cilia and the ciliary level is elevated in orpk mice with polycystic kidney disease. Curr. Biol. 12: 3778-380.

Pazour, G.J., Dickert, B.L., Vucica, Y., Seeley, E.S., Rosenbaum, J.L., Witman, G.B. and Cole, D.G. 2000. Chlamydomonas IFT88 and its mouse homologue, polycystic kidney disease gene Tg737, are required for assembly of cilia and flagella. J. Cell Biol. 151: 709-718.

Pazour, G.J., Dickert, B.L., and Witman, G.B. 1999. The DHC1b (DHC2) isoform of cytoplasmic dynein is required for flagellar assembly. J. Cell Biol. 144: 473-481

Pazour, G.J., Wilkerson, C.G., and Witman, G.B. 1998. A dynein light chain is essential for the retrograde particle movement of intraflagellar transport (IFT). J. Cell Biol. 141: 979-992.

Pazour, G.J., Sineschekov, O.A., and Witman, G.B. 1995. Mutational analysis of the phototransduction pathway of Chlamydomonas reinhardtii. J. Cell Biol. 131: 427-440.

Office: B2-213
Phone: 508-856-8078
Fax: 508-856-5612
E-mail: Gregory.Pazour@umassmed.edu
Keywords: Genetic Systems, Cell Biology, Intracellular Trafficking

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