Section: Figures

Janet Stein, Ph.D.

Academic Role: Professor

Faculty Appointment(s) In:
   Cell Biology

Figure

Regulation of histone gene expression during the cell cycle. Occupancy of the four principal regulatory elements of the histone H4 gene promoter is schematically illustrated during the S phase of the cell cycle when transcription is maximal (top panel) and during the G1/G2/mitotic periods of the cell cycle (middle panel). The lower panel illustrates complete loss of transcription factor complexes at Sites II, III and IV with the onset of differentiation. At this time transcription is completely downregulated.

Office: S3-310
Phone: 508-856-4996
E-mail: Janet.Stein@umassmed.edu
Keywords: Stem Cell Biology, Cancer Biology, Cell Biology, Cell Cycle, Gene Regulation

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