Section: Rotations

Postdoctoral Position Available

Lab Page Link

Greenfield Sluder, Ph.D.

Academic Role: Professor

Faculty Appointment(s) In:
   Cell Biology

Other Affiliation(s):
   Cell Dynamics Group
   Interdisciplinary Graduate Program

Potential Rotation Projects

We favor having students work independently on defined projects that have promise of completion during the study period.

Project #1: Use a frog egg extract that supports multiple rounds of centrosome duplication in vitro to investigate the role of various high interest kinases in the control of centrosome duplication. Also, we can use these extracts to further investigate how various other proteins interact with the centrosome to influence its duplication.

Hinchcliffe, E.H., C. Li, E.A. Thompson, J.L. Maller and G. Sluder. 1999. Requirement of Cdk2-cyclin E activity for repeated centrosome reproduction in Xenopus egg extract. Science 283:851-854.

Project #2: Use microsurgery and immunofluorescence on BSC-1 cells to further investigate how centrioles influence the interphase progression of the cell cycle.

Hinchcliffe, E.H., F.J. Miller, M. Cham, A. Khodjakov and G. Sluder. 2001. Requirement of a centrosomal activity for cell cycle progression through G1 into S phase. Science 291: 1547-1550.

Office: Biotech IV, Suite 324
Phone: 508-856-8651
E-mail: Greenfield.Sluder@umassmed.edu
Keywords: Biophysics, Cell Biology, Cell Cycle

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Postdoctoral Position Available A postdoctoral position is available to study in this laboratory. Contact Dr. Sluder for additional details.